Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of … JC Munday, AA Eze, N Baker, L Glover, C Clucas, D Aguinaga Andrés, ... Journal of Antimicrobial Chemotherapy 69 (3), 651-663, 2014 | 138 | 2014 |
Tools for detection of schistosomiasis in resource limited settings O Ajibola, BH Gulumbe, AA Eze, E Obishakin Medical Sciences 6 (2), 39, 2018 | 99 | 2018 |
Self-medication with antibiotics, attitude and knowledge of antibiotic resistance among community residents and undergraduate students in Northwest Nigeria O Ajibola, OA Omisakin, AA Eze, SA Omoleke Diseases 6 (2), 32, 2018 | 94 | 2018 |
Synthesis and structure–activity analysis of new phosphonium salts with potent activity against African trypanosomes A Taladriz, A Healy, EJ Flores Perez, V Herrero Garcia, C Rios Martinez, ... Journal of Medicinal Chemistry 55 (6), 2606-2622, 2012 | 66 | 2012 |
Typhoid fever diagnosis in endemic countries: a clog in the wheel of progress? O Ajibola, MB Mshelia, BH Gulumbe, AA Eze Medicina 54 (2), 23, 2018 | 65 | 2018 |
Functional expression of TcoAT1 reveals it to be a P1-type nucleoside transporter with no capacity for diminazene uptake JC Munday, KER López, AA Eze, V Delespaux, J Van Den Abbeele, ... International Journal for Parasitology: Drugs and Drug Resistance 3, 69-76, 2013 | 62 | 2013 |
Structure–activity relationships of synthetic cordycepin analogues as experimental therapeutics for African trypanosomiasis SK Vodnala, T Lundbäck, E Yeheskieli, B Sjöberg, AL Gustavsson, ... Journal of medicinal chemistry 56 (24), 9861-9873, 2013 | 60 | 2013 |
The diamidine diminazene aceturate is a substrate for the high-affinity pentamidine transporter: implications for the development of high resistance levels in trypanosomes IA Teka, AJN Kazibwe, N El-Sabbagh, MI Al-Salabi, CP Ward, AA Eze, ... Molecular pharmacology 80 (1), 110-116, 2011 | 56 | 2011 |
Functional analysis of drug resistance‐associated mutations in the Trypanosoma brucei adenosine transporter 1 (TbAT1) and the proposal of a structural model for … JC Munday, DNA Tagoe, AA Eze, JAM Krezdorn, KE Rojas López, ... Molecular microbiology 96 (4), 887-900, 2015 | 47 | 2015 |
Urogenital schistosomiasis is associated with signatures of microbiome dysbiosis in Nigerian adolescents O Ajibola, AD Rowan, CO Ogedengbe, MB Mshelia, DJ Cabral, AA Eze, ... Scientific reports 9 (1), 829, 2019 | 42 | 2019 |
Functional and genetic evidence that nucleoside transport is highly conserved in Leishmania species: Implications for pyrimidine-based chemotherapy KJH Alzahrani, JAM Ali, AA Eze, WL Looi, DNA Tagoe, DJ Creek, ... International Journal for Parasitology: Drugs and Drug Resistance 7 (2), 206-226, 2017 | 40 | 2017 |
Effect of Hibiscus sabdariffa on Blood Pressure and Electrolyte Profile of Mild to Moderate Hypertensive Nigerians: A Comparative Study with Hydrochlorothiazide AAE DC Nwachukwu, E Aneke, NZ Nwachukwu, LFO Obika, UI Nwagha Nigerian journal of clinical practice 18 (6), 762-770, 2015 | 40 | 2015 |
Reduced mitochondrial membrane potential Is a late adaptation of Trypanosoma brucei brucei to isometamidium preceded by mutations in the γ subunit of the F1Fo-ATPase AA Eze, MK Gould, JC Munday, DNA Tagoe, V Stelmanis, A Schnaufer, ... PLoS neglected tropical diseases 10 (8), e0004791, 2016 | 39 | 2016 |
Animal African Trypanosomiasis in Nigeria: A long way from elimination/eradication C Isaac, JA Ohiolei, F Ebhodaghe, IB Igbinosa, AA Eze Acta Tropica 176, 323-331, 2017 | 36 | 2017 |
Bioassay-guided isolation of active principles from Nigerian medicinal plants identifies new trypanocides with low toxicity and no cross-resistance to diamidines and arsenicals GU Ebiloma, JO Igoli, E Katsoulis, AM Donachie, A Eze, AI Gray, ... Journal of ethnopharmacology 202, 256-264, 2017 | 31 | 2017 |
Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei AH Alghamdi, JC Munday, GD Campagnaro, D Gurvic, F Svensson, ... Elife 9, e56416, 2020 | 22 | 2020 |
A New Nonpolar N-Hydroxy Imidazoline Lead Compound with Improved Activity in a Murine Model of Late-Stage Trypanosoma brucei brucei Infection Is Not Cross … CH Ríos Martínez, F Miller, K Ganeshamoorthy, F Glacial, M Kaiser, ... Antimicrobial agents and chemotherapy 59 (2), 890-904, 2015 | 19 | 2015 |
Sustainable elimination (Zero Cases) of sleeping sickness: how far are we from achieving this goal? PI Akazue, GU Ebiloma, O Ajibola, C Isaac, K Onyekwelu, CO Ezeh, ... Pathogens 8 (3), 135, 2019 | 14 | 2019 |
Prevalence of trypanosome infection in tsetse flies from Oji River and Emene axis of Enugu State, Nigeria: a preliminary report KC Onyekwelu, FE Ejezie, AA Eze, JE Ikekpeazu, RC Ezeh, GC Edeh Tropical Parasitology 7 (2), 98-102, 2017 | 14 | 2017 |
Nephroprotective activity of stem bark extracts of Canarium Schweinfurthii on Acetaminophen-Induced renal injuries in rats NCA CN Okwuosa, PU Achukwu Achukwu, DC Nwachukwu, AA Eze International Journal of Medicine and Health Development 14 (1), 2009 | 12 | 2009 |