BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans U Sahin, A Muik, I Vogler, E Derhovanessian, LM Kranz, M Vormehr, ... Nature 595 (7868), 572-577, 2021 | 644 | 2021 |
A phase Ib trial of personalized neoantigen therapy plus anti-PD-1 in patients with advanced melanoma, non-small cell lung cancer, or bladder cancer PA Ott, S Hu-Lieskovan, B Chmielowski, R Govindan, A Naing, ... Cell 183 (2), 347-362. e24, 2020 | 436 | 2020 |
Neutralization of SARS-CoV-2 Omicron by BNT162b2 mRNA vaccine–elicited human sera A Muik, BG Lui, AK Wallisch, M Bacher, J Mühl, J Reinholz, O Ozhelvaci, ... Science 375 (6581), 678-680, 2022 | 335 | 2022 |
Single-cell RNA sequencing reveals a signature of sexual commitment in malaria parasites A Poran, C Nötzel, O Aly, N Mencia-Trinchant, CT Harris, ML Guzman, ... Nature 551 (7678), 95-99, 2017 | 224 | 2017 |
DNA methylation disruption reshapes the hematopoietic differentiation landscape F Izzo, SC Lee, A Poran, R Chaligne, F Gaiti, B Gross, RR Murali, ... Nature genetics 52 (4), 378-387, 2020 | 206 | 2020 |
Defining HLA-II ligand processing and binding rules with mass spectrometry enhances cancer epitope prediction JG Abelin, D Harjanto, M Malloy, P Suri, T Colson, SP Goulding, ... Immunity 51 (4), 766-779. e17, 2019 | 205 | 2019 |
BNT162b2 induces SARS-CoV-2-neutralising antibodies and T cells in humans U Sahin, A Muik, I Vogler, E Derhovanessian, LM Kranz, M Vormehr, ... MedRxiv, 2020.12. 09.20245175, 2020 | 184 | 2020 |
T cell receptor repertoires of mice and humans are clustered in similarity networks around conserved public CDR3 sequences A Madi, A Poran, E Shifrut, S Reich-Zeliger, E Greenstein, I Zaretsky, ... Elife 6, e22057, 2017 | 146 | 2017 |
Revisiting the initial steps of sexual development in the malaria parasite Plasmodium falciparum C Bancells, O Llorà-Batlle, A Poran, C Nötzel, N Rovira-Graells, ... Nature microbiology 4 (1), 144-154, 2019 | 128 | 2019 |
Single-cell TCRseq: paired recovery of entire T-cell alpha and beta chain transcripts in T-cell receptors from single-cell RNAseq D Redmond, A Poran, O Elemento Genome Medicine 8 (1), 1-12, 2016 | 125 | 2016 |
Sequence-based prediction of SARS-CoV-2 vaccine targets using a mass spectrometry-based bioinformatics predictor identifies immunogenic T cell epitopes A Poran, D Harjanto, M Malloy, CM Arieta, DA Rothenberg, D Lenkala, ... Genome medicine 12, 1-15, 2020 | 83 | 2020 |
Personalized neoantigen vaccine NEO-PV-01 with chemotherapy and anti-PD-1 as first-line treatment for non-squamous non-small cell lung cancer MM Awad, R Govindan, KN Balogh, DR Spigel, EB Garon, ME Bushway, ... Cancer Cell 40 (9), 1010-1026. e11, 2022 | 78 | 2022 |
Generation of pulmonary neuroendocrine cells and SCLC-like tumors from human embryonic stem cells HJ Chen, A Poran, AM Unni, SX Huang, O Elemento, HW Snoeck, ... Journal of Experimental Medicine 216 (3), 674-687, 2019 | 76 | 2019 |
High-resolution mouse subventricular zone stem-cell niche transcriptome reveals features of lineage, anatomy, and aging XP Xie, DR Laks, D Sun, A Poran, AM Laughney, Z Wang, J Sam, ... Proceedings of the National Academy of Sciences 117 (49), 31448-31458, 2020 | 45 | 2020 |
Combined TCR repertoire profiles and blood cell phenotypes predict melanoma patient response to personalized neoantigen therapy plus anti-PD-1 A Poran, J Scherer, ME Bushway, R Besada, KN Balogh, A Wanamaker, ... Cell Reports Medicine 1 (8), 2020 | 38 | 2020 |
The T-cell-directed vaccine BNT162b4 encoding conserved non-spike antigens protects animals from severe SARS-CoV-2 infection CM Arieta, YJ Xie, DA Rothenberg, H Diao, D Harjanto, S Meda, ... Cell 186 (11), 2392-2409. e21, 2023 | 32 | 2023 |
Early computational detection of potential high-risk SARS-CoV-2 variants K Beguir, MJ Skwark, Y Fu, T Pierrot, NL Carranza, A Laterre, I Kadri, ... Computers in biology and medicine 155, 106618, 2023 | 29 | 2023 |
Progressive loss of conserved spike protein neutralizing antibody sites in Omicron sublineages is balanced by preserved T cell immunity A Muik, BG Lui, J Quandt, H Diao, Y Fu, M Bacher, J Gordon, A Toker, ... Cell Reports 42 (8), 2023 | 21 | 2023 |
Sequence-based prediction of vaccine targets for inducing T cell responses to SARS-CoV-2 utilizing the bioinformatics predictor RECON A Poran, D Harjanto, M Malloy, MS Rooney, L Srinivasan, RB Gaynor bioRxiv, 2020.04. 06.027805, 2020 | 21 | 2020 |
Neutralization of SARS-CoV-2 Omicron pseudovirus by BNT162b2 vaccine-elicited human sera A Muik, BG Lui, AK Wallisch, M Bacher, J Mühl, J Reinholz, O Ozhelvaci, ... medRxiv, 2021.12. 22.21268103, 2021 | 10 | 2021 |