Bacterial genotoxin colibactin promotes colon tumour growth by inducing a senescence-associated secretory phenotype A Cougnoux, G Dalmasso, R Martinez, E Buc, J Delmas, L Gibold, ... Gut 63 (12), 1932-1942, 2014 | 445 | 2014 |
The bacterial genotoxin colibactin promotes colon tumor growth by modifying the tumor microenvironment G Dalmasso, A Cougnoux, J Delmas, A Darfeuille-Michaud, R Bonnet Gut microbes 5 (5), 675-680, 2014 | 250 | 2014 |
High incidence of unrecognized visceral/neurological late-onset Niemann-Pick disease, type C1, predicted by analysis of massively parallel sequencing data sets CA Wassif, JL Cross, J Iben, L Sanchez-Pulido, A Cougnoux, FM Platt, ... Genetics in Medicine 18 (1), 41-48, 2016 | 216 | 2016 |
Pituitary adenoma with paraganglioma/pheochromocytoma (3PAs) and succinate dehydrogenase defects in humans and mice P Xekouki, E Szarek, P Bullova, A Giubellino, M Quezado, ... The Journal of Clinical Endocrinology & Metabolism 100 (5), E710-E719, 2015 | 155 | 2015 |
ClbP is a prototype of a peptidase subgroup involved in biosynthesis of nonribosomal peptides D Dubois, O Baron, A Cougnoux, J Delmas, N Pradel, M Boury, ... Journal of Biological Chemistry 286 (41), 35562-35570, 2011 | 115 | 2011 |
Small-molecule inhibitors prevent the genotoxic and protumoural effects induced by colibactin-producing bacteria A Cougnoux, J Delmas, L Gibold, T Faïs, C Romagnoli, F Robin, ... Gut 65 (2), 278-285, 2016 | 85 | 2016 |
Analysis of structure–function relationships in the colibactin-maturating enzyme ClbP A Cougnoux, L Gibold, F Robin, D Dubois, N Pradel, ... Journal of molecular biology 424 (3-4), 203-214, 2012 | 74 | 2012 |
A dual apolipoprotein C-II mimetic–apolipoprotein C-III antagonist peptide lowers plasma triglycerides A Wolska, L Lo, DO Sviridov, M Pourmousa, M Pryor, SS Ghosh, R Kakkar, ... Science translational medicine 12 (528), eaaw7905, 2020 | 67 | 2020 |
Microglia activation in Niemann–Pick disease, type C1 is amendable to therapeutic intervention A Cougnoux, RA Drummond, AL Collar, JR Iben, A Salman, H Westgarth, ... Human molecular genetics 27 (12), 2076-2089, 2018 | 66 | 2018 |
Necroptosis in Niemann–Pick disease, type C1: a potential therapeutic target A Cougnoux, C Cluzeau, S Mitra, R Li, I Williams, K Burkert, X Xu, ... Cell death & disease 7 (3), e2147-e2147, 2016 | 62 | 2016 |
FTY720/fingolimod increases NPC1 and NPC2 expression and reduces cholesterol and sphingolipid accumulation in Niemann-Pick type C mutant fibroblasts J Newton, NC Hait, M Maceyka, A Colaco, M Maczis, CA Wassif, ... The FASEB Journal 31 (4), 1719, 2017 | 49 | 2017 |
Chromosome-mediated OXA-48 carbapenemase in highly virulent Escherichia coli R Beyrouthy, F Robin, A Cougnoux, G Dalmasso, A Darfeuille-Michaud, ... Journal of Antimicrobial Chemotherapy 68 (7), 1558-1561, 2013 | 45 | 2013 |
Evaluation of age of death in Niemann-Pick disease, type C: Utility of disease support group websites to understand natural history SE Bianconi, DI Hammond, NY Farhat, AD Do, K Jenkins, A Cougnoux, ... Molecular genetics and metabolism 126 (4), 466-469, 2019 | 43 | 2019 |
Necroptosis inhibition as a therapy for Niemann-Pick disease, type C1: Inhibition of RIP kinases and combination therapy with 2-hydroxypropyl-β-cyclodextrin A Cougnoux, S Clifford, A Salman, SL Ng, J Bertin, FD Porter Molecular genetics and metabolism 125 (4), 345-350, 2018 | 30 | 2018 |
The role of autophagy in the degradation of misfolded HLA–B27 heavy chains F Navid, G Layh‐Schmitt, KA Sikora, A Cougnoux, RA Colbert Arthritis & rheumatology 70 (5), 746-755, 2018 | 30 | 2018 |
Antibiotic activity of Escherichia coli against multiresistant Staphylococcus aureus T Faïs, A Cougnoux, G Dalmasso, F Laurent, J Delmas, R Bonnet Antimicrobial agents and chemotherapy 60 (11), 6986-6988, 2016 | 29 | 2016 |
Abnormal LAMP1 glycosylation may play a role in Niemann-Pick disease, type C pathology NX Cawley, C Sojka, A Cougnoux, AT Lyons, ER Nicoli, CA Wassif, ... PLoS One 15 (1), e0227829, 2020 | 27 | 2020 |
Identification of novel pathways associated with patterned cerebellar purkinje neuron degeneration in niemann-pick disease, type C1 KB Martin, IM Williams, CV Cluzeau, A Cougnoux, RK Dale, JR Iben, ... International Journal of Molecular Sciences 21 (1), 292, 2019 | 27 | 2019 |
Targeting colorectal cancer-associated bacteria: A new area of research for personalized treatments T Faïs, J Delmas, A Cougnoux, G Dalmasso, R Bonnet Gut Microbes 7 (4), 329-333, 2016 | 26 | 2016 |
Single cell transcriptome analysis of niemann–pick disease, type c1 cerebella A Cougnoux, JC Yerger, M Fellmeth, J Serra-Vinardell, K Martin, F Navid, ... International Journal of Molecular Sciences 21 (15), 5368, 2020 | 24 | 2020 |