Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease JH Kordower, ME Emborg, J Bloch, SY Ma, Y Chu, L Leventhal, J McBride, ... Science 290 (5492), 767-773, 2000 | 1522 | 2000 |
Age‐related declines in nigral neuronal function correlate with motor impairments in rhesus monkeys ME Emborg, SY Ma, EJ Mufson, AI Levey, MD Taylor, WD Brown, ... Journal of Comparative Neurology 401 (2), 253-265, 1998 | 323 | 1998 |
Lentivirally delivered glial cell line-derived neurotrophic factor increases the number of striatal dopaminergic neurons in primate models of nigrostriatal degeneration S Palfi, L Leventhal, Y Chu, SY Ma, M Emborg, R Bakay, N Deglon, ... Journal of Neuroscience 22 (12), 4942-4954, 2002 | 249 | 2002 |
Specification of midbrain dopamine neurons from primate pluripotent stem cells J Xi, Y Liu, H Liu, H Chen, ME Emborg, SC Zhang Stem cells 30 (8), 1655-1663, 2012 | 241 | 2012 |
Lentiviral gene transfer to the nonhuman primate brain JH Kordower, J Bloch, SY Ma, Y Chu, S Palfi, BZ Roitberg, M Emborg, ... Experimental neurology 160 (1), 1-16, 1999 | 235 | 1999 |
Contributions of non-human primates to neuroscience research JP Capitanio, ME Emborg The Lancet 371 (9618), 1126-1135, 2008 | 229 | 2008 |
Evaluation of animal models of Parkinson's disease for neuroprotective strategies ME Emborg Journal of neuroscience methods 139 (2), 121-143, 2004 | 228 | 2004 |
The PPAR-γ agonist pioglitazone modulates inflammation and induces neuroprotection in parkinsonian monkeys CR Swanson, V Joers, V Bondarenko, K Brunner, HA Simmons, ... Journal of neuroinflammation 8, 1-14, 2011 | 205 | 2011 |
Nonhuman primate models of Parkinson's disease ME Emborg ILAR journal 48 (4), 339-355, 2007 | 196 | 2007 |
Induced pluripotent stem cell-derived neural cells survive and mature in the nonhuman primate brain ME Emborg, Y Liu, J Xi, X Zhang, Y Yin, J Lu, V Joers, C Swanson, ... Cell reports 3 (3), 646-650, 2013 | 169 | 2013 |
Subthalamic glutamic acid decarboxylase gene therapy: changes in motor function and cortical metabolism ME Emborg, M Carbon, JE Holden, MJ During, Y Ma, C Tang, J Moirano, ... Journal of Cerebral Blood Flow & Metabolism 27 (3), 501-509, 2007 | 150 | 2007 |
Pioglitazone in early Parkinson's disease: a phase 2, multicentre, double-blind, randomised trial L Neurol Lancet Neurol 14 (8), 795-803, 2015 | 129 | 2015 |
Overexpressing corticotropin-releasing factor in the primate amygdala increases anxious temperament and alters its neural circuit NH Kalin, AS Fox, R Kovner, MK Riedel, EM Fekete, PH Roseboom, ... Biological Psychiatry 80 (5), 345-355, 2016 | 122 | 2016 |
Strategies for improving animal models for regenerative medicine J Cibelli, ME Emborg, DJ Prockop, M Roberts, G Schatten, M Rao, ... Cell stem cell 12 (3), 271-274, 2013 | 106 | 2013 |
The NIH somatic cell genome editing program K Saha, EJ Sontheimer, PJ Brooks, MR Dwinell, CA Gersbach, DR Liu, ... Nature 592 (7853), 195-204, 2021 | 102 | 2021 |
Chronic ischemic stroke model in cynomolgus monkeys: behavioral, neuroimaging and anatomical study B Roitberg, N Khan, E Tuccar, K Kompoliti, Y Chu, N Alperin, ... Neurological research 25 (1), 68-78, 2003 | 96 | 2003 |
GDNF-secreting human neural progenitor cells increase tyrosine hydroxylase and VMAT2 expression in MPTP-treated cynomolgus monkeys ME Emborg, AD Ebert, J Moirano, S Peng, M Suzuki, E Capowski, V Joers, ... Cell transplantation 17 (4), 383-395, 2008 | 92 | 2008 |
Distribution of high affinity choline transporter immunoreactivity in the primate central nervous system L Kus, E Borys, Y Ping Chu, SM Ferguson, RD Blakely, ME Emborg, ... Journal of Comparative Neurology 463 (3), 341-357, 2003 | 84 | 2003 |
Beyond access vs. protection in trials of innovative therapies AJ London, J Kimmelman, ME Emborg Science 328 (5980), 829-830, 2010 | 83 | 2010 |
Autologous transplant therapy alleviates motor and depressive behaviors in parkinsonian monkeys Y Tao, SC Vermilyea, M Zammit, J Lu, M Olsen, JM Metzger, L Yao, ... Nature medicine 27 (4), 632-639, 2021 | 82 | 2021 |