CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity ML Burr, CE Sparbier, YC Chan, JC Williamson, K Woods, PA Beavis, ... Nature 549 (7670), 101-105, 2017 | 767 | 2017 |
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer ML Burr, CE Sparbier, KL Chan, YC Chan, A Kersbergen, EYN Lam, ... Cancer cell 36 (4), 385-401. e8, 2019 | 464 | 2019 |
Dynamic molecular monitoring reveals that SWI–SNF mutations mediate resistance to ibrutinib plus venetoclax in mantle cell lymphoma R Agarwal, YC Chan, CS Tam, T Hunter, D Vassiliadis, CE Teh, ... Nature medicine 25 (1), 119-129, 2019 | 171 | 2019 |
Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia CC Bell, KA Fennell, YC Chan, F Rambow, MM Yeung, D Vassiliadis, ... Nature communications 10 (1), 2723, 2019 | 152 | 2019 |
Principles and mechanisms of non-genetic resistance in cancer CC Bell, O Gilan British journal of cancer 122 (4), 465-472, 2020 | 141 | 2020 |
Click chemistry enables preclinical evaluation of targeted epigenetic therapies DS Tyler, J Vappiani, T Cañeque, EYN Lam, A Ward, O Gilan, YC Chan, ... Science 356 (6345), 1397-1401, 2017 | 132 | 2017 |
A high-throughput screening strategy for detecting CRISPR-Cas9 induced mutations using next-generation sequencing CC Bell, GW Magor, KR Gillinder, AC Perkins BMC genomics 15, 1-7, 2014 | 123 | 2014 |
KLF1-null neonates display hydrops fetalis and a deranged erythroid transcriptome GW Magor, MR Tallack, KR Gillinder, CC Bell, N McCallum, B Williams, ... Blood, The Journal of the American Society of Hematology 125 (15), 2405-2417, 2015 | 102 | 2015 |
Interconversion between tumorigenic and differentiated states in acute myeloid leukemia MD McKenzie, M Ghisi, EP Oxley, S Ngo, L Cimmino, C Esnault, R Liu, ... Cell stem cell 25 (2), 258-272. e9, 2019 | 85 | 2019 |
CDK4/6 inhibition reprograms the breast cancer enhancer landscape by stimulating AP-1 transcriptional activity AC Watt, P Cejas, MJ DeCristo, O Metzger-Filho, EYN Lam, X Qiu, ... Nature Cancer 2 (1), 34-48, 2021 | 63 | 2021 |
Direct targets of pSTAT5 signalling in erythropoiesis KR Gillinder, H Tuckey, CC Bell, GW Magor, S Huang, MD Ilsley, ... PLoS One 12 (7), e0180922, 2017 | 49 | 2017 |
Epigenetic therapies in acute myeloid leukemia: where to from here? KA Fennell, CC Bell, MA Dawson Blood, The Journal of the American Society of Hematology 134 (22), 1891-1901, 2019 | 46 | 2019 |
An Erg-driven transcriptional program controls B cell lymphopoiesis AP Ng, HD Coughlan, S Hediyeh-Zadeh, K Behrens, TM Johanson, ... Nature Communications 11 (1), 3013, 2020 | 35 | 2020 |
The Evx1/Evx1as gene locus regulates anterior-posterior patterning during gastrulation CC Bell, PP Amaral, A Kalsbeek, GW Magor, KR Gillinder, P Tangermann, ... Scientific reports 6 (1), 26657, 2016 | 31 | 2016 |
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes CE Sparbier, A Gillespie, J Gomez, N Kumari, A Motazedian, KL Chan, ... Nature cell biology 25 (2), 258-272, 2023 | 15 | 2023 |
Transcription factors use a unique combination of cofactors to potentiate different promoter-dependent steps in transcription CC Bell, L Talarmain, L Scolamiero, EYN Lam, CS Ang, O Gilan, ... bioRxiv, 2022.10. 25.513774, 2022 | 7 | 2022 |
CRISPR–ChIP reveals selective regulation of H3K79me2 by Menin in MLL leukemia O Gilan, L Talarmain, CC Bell, D Neville, K Knezevic, DT Ferguson, ... Nature Structural & Molecular Biology 30 (10), 1592-1606, 2023 | 4 | 2023 |
TFIID and MYB Share a Therapeutic Handshake in AML CC Bell, MA Dawson Cancer Cell 33 (1), 1-3, 2018 | 4 | 2018 |
KLF1 acts as a pioneer transcription factor via SMARCA4 to open chromatin and facilitate redeployment of an enhancer complex containing GATA1 and SCL GW Magor, KR Gillinder, S Huang, MD Ilsley, C Bell, AC Perkins Blood 140 (Supplement 1), 696-697, 2022 | 2 | 2022 |
LINE-1 retrotransposon activation intrinsic to interneuron development GO Bodea, JM Botto, ME Ferreiro, FJ Sanchez-Luque, ... bioRxiv, 2022.03. 20.485017, 2022 | 2 | 2022 |