Isolation of cerebral capillaries from fresh human brain tissue AMS Hartz, JA Schulz, BS Sokola, SE Edelmann, AN Shen, RG Rempe, ... JoVE (Journal of Visualized Experiments), e57346, 2018 | 28 | 2018 |
Characterization and comparison of human glioblastoma models JA Schulz, LT Rodgers, RJ Kryscio, AMS Hartz, B Bauer BMC cancer 22 (1), 844, 2022 | 19 | 2022 |
ABCB1 and ABCG2 regulation at the blood-brain barrier: potential new targets to improve brain drug delivery JA Schulz, AMS Hartz, B Bauer Pharmacological Reviews 75 (5), 815-853, 2023 | 15 | 2023 |
Plasma protein-mediated uptake and contradictions to the free drug hypothesis: a critical review JA Schulz, DM Stresser, JC Kalvass Drug metabolism reviews 55 (3), 205-238, 2023 | 13 | 2023 |
Drug delivery to primary and metastatic brain tumors: challenges and opportunities S Talele, AS Mohammad, JA Schulz, B Bauer, AMS Hartz, JN Sarkaria, ... Drug Delivery to the Brain: Physiological Concepts, Methodologies and …, 2022 | 2 | 2022 |
Assumptions Underlying Hepatic Clearance Models: Recognizing the Influence of Saturable Protein Binding on Driving Force Concentration and Discrimination Between Models of … JAS Pauly, J Wang, CJ Phipps, JC Kalvass Drug Metabolism and Disposition 51 (8), 1046-1052, 2023 | 1 | 2023 |
CSIG-32. DUAL PI3K/Akt INHIBITION TO OVERCOME THE P-gp/BCRP DRUG EFFLUX SYSTEM FOR IMPROVED DRUG DELIVERY IN GLIOBLASTOMA THERAPY A Hartz, J Schulz, B Sokola, B Bauer Neuro-oncology 20 (Suppl 6), vi50, 2018 | 1 | 2018 |
Improving in vitro clearance assay performance and prediction accuracy with advanced human hepatocyte models for highly stable RO5 and BRO5 compounds D Kukla, J Pauly, C Kalvass, G Jenkins, D Stresser Drug Metabolism and Pharmacokinetics 55, 100820, 2024 | | 2024 |
Hepatocyte Uptake and Loss Assay (HUpLA): Proof-of-Concept of an All-in-One System for Measuring Hepatic Influx, Egress, and Metabolic Clearance Based on the Extended Clearance … JAS Pauly, E Sande, M Feng, YT Wang, DM Stresser, JC Kalvass Drug Metabolism and Disposition, 2024 | | 2024 |
442 Repurposing FDA-approved PI3K/Akt Inhibitors to Improve Anti-Cancer Drug Brain Uptake in Glioblastoma Resection Models L Rodgers, Y Tega, JA Schulz, AMS Hartz, B Bauer Journal of Clinical and Translational Science 6 (s1), 87-87, 2022 | | 2022 |
ABC Transporters in Glioblastoma: Anticancer Drug Transport and Transporter Regulation at the Blood-brain Barrier JA Schulz | | 2021 |