Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis CR Esther Jr, MS Muhlebach, C Ehre, DB Hill, MC Wolfgang, M Kesimer, ... Science translational medicine 11 (486), eaav3488, 2019 | 187 | 2019 |
Membrane surfaces regulate assembly of ribonucleoprotein condensates WT Snead, AP Jalihal, TM Gerbich, I Seim, Z Hu, AS Gladfelter Nature Cell Biology 24 (4), 461-470, 2022 | 93 | 2022 |
Dilute phase oligomerization can oppose phase separation and modulate material properties of a ribonucleoprotein condensate I Seim, AE Posey, WT Snead, BM Stormo, D Klotsa, RV Pappu, ... Proceedings of the National Academy of Sciences 119 (13), e2120799119, 2022 | 58 | 2022 |
Double-stranded RNA drives SARS-CoV-2 nucleocapsid protein to undergo phase separation at specific temperatures CA Roden, Y Dai, CA Giannetti, I Seim, M Lee, R Sealfon, GA McLaughlin, ... Nucleic acids research 50 (14), 8168-8192, 2022 | 46 | 2022 |
Technological strategies to estimate and control diffusive passage times through the mucus barrier in mucosal drug delivery JM Newby, I Seim, M Lysy, Y Ling, J Huckaby, SK Lai, MG Forest Advanced drug delivery reviews 124, 64-81, 2018 | 45 | 2018 |
Designed, highly expressing, thermostable dengue virus 2 envelope protein dimers elicit quaternary epitope antibodies ST Kudlacek, S Metz, D Thiono, AM Payne, TTN Phan, S Tian, ... Science advances 7 (42), eabg4084, 2021 | 24 | 2021 |
Role of spatial patterning of N-protein interactions in SARS-CoV-2 genome packaging I Seim, CA Roden, AS Gladfelter Biophysical journal 120 (14), 2771-2784, 2021 | 23 | 2021 |
Dynamical control enables the formation of demixed biomolecular condensates AZ Lin, KM Ruff, F Dar, A Jalihal, MR King, JM Lalmansingh, AE Posey, ... Nature communications 14 (1), 7678, 2023 | 20 | 2023 |
Mucus and mucus flake composition and abundance reflect inflammatory and infection status in cystic fibrosis MR Markovetz, IC Garbarine, CB Morrison, WJ Kissner, I Seim, MG Forest, ... Journal of Cystic Fibrosis 21 (6), 959-966, 2022 | 15 | 2022 |
Biophysical properties governing septin assembly BL Woods, I Seim, J Liu, G McLaughlin, KS Cannon, AS Gladfelter bioRxiv, 2021.03. 22.436414, 2021 | 7 | 2021 |
A gene duplication of a septin reveals a developmentally regulated filament length control mechanism KS Cannon, JM Vargas-Muniz, N Billington, I Seim, J Ekena, JR Sellers, ... The Journal of cell biology 222 (3), 2023 | 4 | 2023 |
Measurement error correction in particle tracking microrheology Y Ling, M Lysy, I Seim, J Newby, DB Hill, J Cribb, MG Forest The Annals of Applied Statistics 16 (3), 1747-1773, 2022 | 4 | 2022 |
Intrinsically disordered sequences can tune fungal growth and the cell cycle for specific temperatures BM Stormo, GA McLaughlin, AP Jalihal, LK Frederick, SJ Cole, I Seim, ... Current Biology, 2024 | | 2024 |
Multi-Scale Studies of Molecular Self-Assembly in Biology I Seim The University of North Carolina at Chapel Hill, 2022 | | 2022 |
Evidence that self-similar microrheology of highly entangled polymeric solutions scales robustly with, and is tunable by, polymer concentration I Seim, JA Cribb, JM Newby, P Vasquez, M Lysy, MG Forest, DB Hill arXiv preprint arXiv:1810.06649, 2018 | | 2018 |