Inflamm-aging, cytokines and aging: state of the art, new hypotheses on the role of mitochondria and new perspectives from systems biology S Salvioli, M Capri, S Valensin, P Tieri, D Monti, E Ottaviani, C Franceschi Current pharmaceutical design 12 (24), 3161-3171, 2006 | 307 | 2006 |
Human models of aging and longevity E Cevenini, L Invidia, F Lescai, S Salvioli, P Tieri, G Castellani, ... Expert opinion on biological therapy 8 (9), 1393-1405, 2008 | 218 | 2008 |
Molecular networks in Network Medicine: Development and applications EK Silverman, HHHW Schmidt, E Anastasiadou, L Altucci, M Angelini, ... Wiley Interdisciplinary Reviews: Systems Biology and Medicine 12 (6), e1489, 2020 | 169 | 2020 |
ACE2 expression and sex disparity in COVID-19 MC Gagliardi, P Tieri, E Ortona, A Ruggieri Cell Death Discovery 6 (1), 37, 2020 | 149 | 2020 |
Gene regulatory network modeling of macrophage differentiation corroborates the continuum hypothesis of polarization states A Palma, AS Jarrah, P Tieri, G Cesareni, F Castiglione Frontiers in physiology 9, 417083, 2018 | 120 | 2018 |
Network, degeneracy and bow tie. Integrating paradigms and architectures to grasp the complexity of the immune system P Tieri, A Grignolio, A Zaikin, M Mishto, D Remondini, GC Castellani, ... Theoretical Biology and Medical Modelling 7, 1-16, 2010 | 103 | 2010 |
Charting the NF-κB pathway interactome map P Tieri, A Termanini, E Bellavista, S Salvioli, M Capri, C Franceschi PloS one 7 (3), e32678, 2012 | 92 | 2012 |
Systems biology and longevity: an emerging approach to identify innovative anti-aging targets and strategies E Cevenini, E Bellavista, P Tieri, G Castellani, F Lescai, M Francesconi, ... Current pharmaceutical design 16 (7), 802-813, 2010 | 92 | 2010 |
Towards a liquid self: how time, geography, and life experiences reshape the biological identity A Grignolio, M Mishto, AMC Faria, P Garagnani, C Franceschi, P Tieri Frontiers in Immunology 5, 153, 2014 | 72 | 2014 |
Centenarians as super-controls to assess the biological relevance of genetic risk factors for common age-related diseases: a proof of principle on type 2 diabetes P Garagnani, C Giuliani, C Pirazzini, F Olivieri, MG Bacalini, R Ostan, ... AGING 5 (5), 373-385, 2013 | 61 | 2013 |
Network inference and reconstruction in bioinformatics P Tieri, L Farina, M Petti, L Astolfi, P Paci, F Castiglione Encyclopedia of Bioinformatics and Computational Biology, 805-813, 2019 | 59 | 2019 |
Multiscale modelling in immunology: a review A Cappuccio, P Tieri, F Castiglione Briefings in bioinformatics 17 (3), 408-418, 2016 | 56 | 2016 |
The emerging role of ECM crosslinking in T cell mobility as a hallmark of immunosenescence in humans JF Moreau, T Pradeu, A Grignolio, C Nardini, F Castiglione, P Tieri, ... Ageing Research Reviews 35, 322-335, 2017 | 52 | 2017 |
Quantifying the relevance of different mediators in the human immune cell network P Tieri, S Valensin, V Latora, GC Castellani, M Marchiori, D Remondini, ... Bioinformatics 21 (8), 1639-1643, 2005 | 49 | 2005 |
Deep learning in systems medicine H Wang, E Pujos-Guillot, B Comte, JL de Miranda, V Spiwok, I Chorbev, ... Briefings in Bioinformatics 22 (2), 1543-1559, 2021 | 40 | 2021 |
Personalizing physical exercise in a computational model of fuel homeostasis MC Palumbo, M Morettini, P Tieri, F Diele, M Sacchetti, F Castiglione PLoS computational biology 14 (4), e1006073, 2018 | 30 | 2018 |
Integrating Omics data for signaling pathways, interactome reconstruction, and functional analysis P Tieri, A de la Fuente, A Termanini, C Franceschi Bioinformatics for Omics Data: Methods and Protocols, 415-433, 2011 | 28 | 2011 |
Designing a network proximity-based drug repurposing strategy for COVID-19 P Stolfi, L Manni, M Soligo, D Vergni, P Tieri Frontiers in cell and developmental biology 8, 545089, 2020 | 27 | 2020 |
Network and systems medicine: Position paper of the european collaboration on science and technology action on open multiscale systems medicine B Comte, J Baumbach, A Benis, J Basílio, N Debeljak, Å Flobak, ... Network and systems medicine 3 (1), 67-90, 2020 | 26 | 2020 |
X-chromosome-linked miR548am-5p is a key regulator of sex disparity in the susceptibility to mitochondria-mediated apoptosis P Matarrese, P Tieri, S Anticoli, B Ascione, M Conte, C Franceschi, ... Cell death & disease 10 (9), 673, 2019 | 22 | 2019 |