| Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors TC Chou, P Talalay Advances in enzyme regulation 22, 27-55, 1984 | 8334 | 1984 |
| Drug combination studies and their synergy quantification using the Chou-Talalay method TC Chou Cancer research 70 (2), 440-446, 2010 | 5619 | 2010 |
| Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug-combination studies (vol 58, pg 621-681, 2006) TC Chou Pharmacological Reviews 58, 621-681, 2006 | 5560 | 2006 |
| Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian–human immunodeficiency virus infection TW Baba, V Liska, R Hofmann-Lehmann, J Vlasak, W Xu, S Ayehunie, ... Nature medicine 6 (2), 200-206, 2000 | 1110 | 2000 |
| Analysis of combined drug effects: a new look at a very old problem TC Chou, P Talalay Trends in pharmacological sciences 4, 450-454, 1983 | 711 | 1983 |
| Computerized quantitation of synergism and antagonism of taxol, topotecan, and cisplatin against human teratocarcinoma cell growth: a rational approach to clinical protocol design TC Chou, RJ Motzer, Y Tong, GJ Bosl JNCI: Journal of the National Cancer Institute 86 (20), 1517-1524, 1994 | 618 | 1994 |
| Generalized equations for the analysis of inhibitions of Michaelis‐Menten and higher‐order kinetic systems with two or more mutually exclusive and nonexclusive inhibitors TC CHOU, P Talalay European Journal of Biochemistry 115 (1), 207-216, 1981 | 528 | 1981 |
| Derivation and properties of Michaelis-Menten type and Hill type equations for reference ligands TC Chou Journal of theoretical biology 59 (2), 253-276, 1976 | 437 | 1976 |
| The median-effect principle and the combination index for quantitation of synergism and antagonism TC Chou Synergism and antagonism in chemotherapy, 61-102, 1991 | 430 | 1991 |
| CompuSyn for drug combinations: PC software and user’s guide: a computer program for quantitation of synergism and antagonism in drug combinations, and the determination of … TC Chou, N Martin Compusyn Software and User's Guide, 2005 | 420 | 2005 |
| Irinotecan is an active agent in untreated patients with metastatic colorectal cancer. JA Conti, NE Kemeny, LB Saltz, Y Huang, WP Tong, TC Chou, M Sun, ... Journal of clinical oncology 14 (3), 709-715, 1996 | 410 | 1996 |
| A simple generalized equation for the analysis of multiple inhibitions of Michaelis-Menten kinetic systems. TC Chou, P Talalay Journal of Biological Chemistry 252 (18), 6438-6442, 1977 | 387 | 1977 |
| Ribavirin antagonizes the effect of azidothymidine on HIV replication MW Vogt, KL Hartshorn, PA Furman, TC Chou, JA Fyfe, LA Coleman, ... Science 235 (4794), 1376-1379, 1987 | 351 | 1987 |
| Preclinical versus clinical drug combination studies TC Chou Leukemia & lymphoma 49 (11), 2059-2080, 2008 | 311 | 2008 |
| Quantitation of chemopreventive synergism between (-)-epigallocatechin-3-gallate and curcumin in normal, premalignant and malignant human oral epithelial cells. A Khafif, SP Schantz, TC Chou, D Edelstein, PG Sacks Carcinogenesis 19 (3), 419-424, 1998 | 309 | 1998 |
| The total synthesis of dynemicin A leading to development of a fully contained bioreductively activated enediyne prodrug MD Shair, TY Yoon, KK Mosny, TC Chou, SJ Danishefsky Journal of the American Chemical Society 118 (40), 9509-9525, 1996 | 295 | 1996 |
| Remote effects in macrolide formation through ring-forming olefin metathesis: an application to the synthesis of fully active epothilone congeners D Meng, DS Su, A Balog, P Bertinato, EJ Sorensen, SJ Danishefsky, ... Journal of the American Chemical Society 119 (11), 2733-2734, 1997 | 293 | 1997 |
| p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas B Singh, PG Reddy, A Goberdhan, C Walsh, S Dao, I Ngai, TC Chou, ... Genes & development 16 (8), 984-993, 2002 | 290 | 2002 |
| Synergistic inhibition of human immunodeficiency virus in vitro by azidothymidine and recombinant alpha A interferon KL Hartshorn, MW Vogt, TC Chou, RS Blumberg, R Byington, ... Antimicrobial agents and chemotherapy 31 (2), 168-172, 1987 | 281 | 1987 |
| Pharmacokinetic interactions augment toxicities of sirolimus/cyclosporine combinations H Podder, SM Stepkowski, KL Napoli, J Clark, RR Verani, TC Chou, ... Journal of the American Society of Nephrology 12 (5), 1059-1071, 2001 | 280 | 2001 |
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