Epigallocatechin‐3‐gallate, a DYRK1A inhibitor, rescues cognitive deficits in D own syndrome mouse models and in humans R De la Torre, S De Sola, M Pons, A Duchon, MM de Lagran, M Farré, ... Molecular nutrition & food research 58 (2), 278-288, 2014 | 347 | 2014 |
Patient-specific iPSC-derived astrocytes contribute to non-cell-autonomous neurodegeneration in Parkinson's disease A di Domenico, G Carola, C Calatayud, M Pons-Espinal, JP Muñoz, ... Stem cell reports 12 (2), 213-229, 2019 | 335 | 2019 |
Safety and efficacy of cognitive training plus epigallocatechin-3-gallate in young adults with Down's syndrome (TESDAD): a double-blind, randomised, placebo-controlled, phase 2 … R de la Torre, S de Sola, G Hernandez, M Farré, J Pujol, J Rodriguez, ... The Lancet Neurology 15 (8), 801-810, 2016 | 298 | 2016 |
Astrocyte deletion of Bmal1 alters daily locomotor activity and cognitive functions via GABA signalling O Barca-Mayo, M Pons-Espinal, P Follert, A Armirotti, L Berdondini, ... Nature communications 8 (1), 14336, 2017 | 205 | 2017 |
Human DNA methylomes of neurodegenerative diseases show common epigenomic patterns JV Sanchez-Mut, H Heyn, E Vidal, S Moran, S Sayols, R Delgado-Morales, ... Translational psychiatry 6 (1), e718-e718, 2016 | 169 | 2016 |
Environmental enrichment rescues DYRK1A activity and hippocampal adult neurogenesis in TgDyrk1A M Pons-Espinal, MM de Lagran, M Dierssen Neurobiology of disease 60, 18-31, 2013 | 84 | 2013 |
Circadian glucocorticoid oscillations preserve a population of adult hippocampal neural stem cells in the aging brain M Schouten, P Bielefeld, L Garcia-Corzo, EMJ Passchier, S Gradari, ... Molecular Psychiatry 25 (7), 1382-1405, 2020 | 69 | 2020 |
Synergic functions of miRNAs determine neuronal fate of adult neural stem cells M Pons-Espinal, E de Luca, MJ Marzi, R Beckervordersandforth, ... Stem Cell Reports 8 (4), 1046-1061, 2017 | 62 | 2017 |
MiR-135a-5p is critical for exercise-induced adult neurogenesis M Pons-Espinal, C Gasperini, MJ Marzi, C Braccia, A Armirotti, A Pötzsch, ... Stem Cell Reports 12 (6), 1298-1312, 2019 | 50 | 2019 |
Parkinson’s disease patient-specific neuronal networks carrying the LRRK2 G2019S mutation unveil early functional alterations that predate neurodegeneration G Carola, D Malagarriga, C Calatayud, M Pons-Espinal, L Blasco-Agell, ... npj Parkinson's Disease 7 (1), 55, 2021 | 27 | 2021 |
Environmental enrichment induces epigenomic and genome organization changes relevant for cognition S Espeso-Gil, AZ Holik, S Bonnin, S Jhanwar, S Chandrasekaran, ... Frontiers in Molecular Neuroscience 14, 664912, 2021 | 25 | 2021 |
Functional implications of hippocampal adult neurogenesis in intellectual disabilities M Pons-Espinal, MM de Lagran, M Dierssen Amino Acids 45, 113-131, 2013 | 21 | 2013 |
A new SWATH ion library for mouse adult hippocampal neural stem cells C Braccia, MP Espinal, M Pini, DDP Tonelli, A Armirotti Data in Brief 18, 1-8, 2018 | 17 | 2018 |
Dissecting the non-neuronal cell contribution to Parkinson’s disease pathogenesis using induced pluripotent stem cells M Pons-Espinal, L Blasco-Agell, A Consiglio Cellular and Molecular Life Sciences 78, 2081-2094, 2021 | 13 | 2021 |
Long-term labeling of hippocampal neural stem cells by a lentiviral vector H Suh, QG Zhou, I Fernandez-Carasa, GD Clemenson Jr, M Pons-Espinal, ... Frontiers in Molecular Neuroscience 11, 415, 2018 | 10 | 2018 |
Piwil2 (Mili) sustains neurogenesis and prevents cellular senescence in the postnatal hippocampus C Gasperini, K Tuntevski, S Beatini, R Pelizzoli, A Lo Van, D Mangoni, ... EMBO reports 24 (2), e53801, 2023 | 9 | 2023 |
Blocking IL-6 signaling prevents astrocyte-induced neurodegeneration in an iPSC-based model of Parkinson’s disease M Pons-Espinal, L Blasco-Agell, I Fernandez-Carasa, P Andrés-Benito, ... JCI insight 9 (3), 2024 | 7 | 2024 |
iPSC‐based modeling of THD recapitulates disease phenotypes and reveals neuronal malformation A Tristán‐Noguero, I Fernández‐Carasa, C Calatayud, ... EMBO Molecular Medicine 15 (3), e15847, 2023 | 7 | 2023 |
The piRNA pathway sustains adult neurogenesis by reducing protein synthesis and cellular senescence C Gasperini, K Tuntevski, R Pelizzoli, A Lo Van, D Mangoni, RM Cossu, ... bioRxiv, 2020.09. 15.297739, 2020 | 5 | 2020 |
Immunosuppressive tocilizumab prevents astrocyte induced neurotoxicity in hiPSC-LRRK2 Parkinson’s disease by targeting receptor interleukin-6 M Pons-Espinal, L Blasco-Agell, I Fernandez-Carasa, A di Domenico, ... bioRxiv, 2022.08. 23.504918, 2022 | 1 | 2022 |