Phytosphingosine, sphingosine and dihydrosphingosine ceramides in model skin lipid membranes: permeability and biophysics B Školová, A Kováčik, O Tesař, L Opálka, K Vávrová Biochimica et Biophysica Acta (BBA)-Biomembranes 1859 (5), 824-834, 2017 | 77 | 2017 |
Ceramides in the skin barrier K Vávrová, A Kováčik, L Opálka European Pharmaceutical Journal 64 (2), 28-35, 2017 | 77 | 2017 |
Stimulation of PPARα normalizes the skin lipid ratio and improves the skin barrier of normal and filaggrin deficient reconstructed skin L Wallmeyer, D Lehnen, N Eger, M Sochorová, L Opálka, A Kováčik, ... Journal of Dermatological Science 80 (2), 102-110, 2015 | 58 | 2015 |
PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin … M Pichery, A Huchenq, R Sandhoff, M Severino-Freire, S Zaafouri, ... Human Molecular Genetics 26 (10), 1787-1800, 2017 | 55 | 2017 |
Omega-O-Acylceramides in Skin Lipid Membranes: Effects of Concentration, Sphingoid Base, and Model Complexity on Microstructure and Permeability L Opálka, A Kováčik, J Maixner, K Vávrová Langmuir 32 (48), 12894-12904, 2016 | 51 | 2016 |
Scalable synthesis of human ultralong chain ceramides L Opalka, A Kovacik, M Sochorová, J Roh, J Kunes, J Lenco, K Vávrová Organic Letters 17 (21), 5456-5459, 2015 | 50 | 2015 |
Permeability and microstructure of cholesterol-depleted skin lipid membranes and human stratum corneum M Sochorová, P Audrlická, M Červená, A Kováčik, M Kopečná, L Opálka, ... Journal of colloid and interface science 535, 227-238, 2019 | 43 | 2019 |
HILIC/ESI-MS determination of gangliosides and other polar lipid classes in renal cell carcinoma and surrounding normal tissues R Hájek, M Lísa, M Khalikova, R Jirásko, E Cífková, V Študent, D Vrána, ... Analytical and bioanalytical chemistry 410, 6585-6594, 2018 | 41 | 2018 |
Effects of omega-O-acylceramide structures and concentrations in healthy and diseased skin barrier lipid membrane models [S] L Opálka, A Kováčik, P Pullmannová, J Maixner, K Vávrová Journal of lipid research 61 (2), 219-228, 2020 | 36 | 2020 |
Bacterial immunogenic α-galactosylceramide identified in the murine large intestine: dependency on diet and inflammation J von Gerichten, D Lamprecht, L Opálka, D Soulard, C Marsching, R Pilz, ... Journal of lipid research 60 (11), 1892-1904, 2019 | 36 | 2019 |
Synthesis of 6-hydroxyceramide using ruthenium-catalyzed hydrosilylation–protodesilylation. Unexpected formation of a long periodicity lamellar phase in skin lipid membranes A Kováčik, L Opálka, M Šilarová, J Roh, K Vávrová RSC advances 6 (77), 73343-73350, 2016 | 34 | 2016 |
The sphingosine and acyl chains of ceramide [NS] show very different structure and dynamics that challenge our understanding of the skin barrier O Engberg, A Kováčik, P Pullmannová, M Juhaščik, L Opálka, D Huster, ... Angewandte Chemie International Edition 59 (40), 17383-17387, 2020 | 31 | 2020 |
Long and very long lamellar phases in model stratum corneum lipid membranes P Pullmannová, E Ermakova, A Kováčik, L Opálka, J Maixner, J Zbytovská, ... Journal of lipid research 60 (5), 963-971, 2019 | 29 | 2019 |
Non-ionic surfactants as innovative skin penetration enhancers: Insight in the mechanism of interaction with simple 2D stratum corneum model system F Strati, RHH Neubert, L Opálka, A Kerth, G Brezesinski European Journal of Pharmaceutical Sciences 157, 105620, 2021 | 26 | 2021 |
Cellular and metabolic basis for the ichthyotic phenotype in NIPAL4 (Ichthyin)–deficient canines EA Mauldin, D Crumrine, ML Casal, S Jeong, L Opálka, K Vavrova, ... The American Journal of Pathology 188 (6), 1419-1429, 2018 | 25 | 2018 |
Effects of (R)- and (S)-α-Hydroxylation of Acyl Chains in Sphingosine, Dihydrosphingosine, and Phytosphingosine Ceramides on Phase Behavior and … A Kováčik, P Pullmannová, L Opálka, M Šilarová, J Maixner, K Vávrová International Journal of Molecular Sciences 22 (14), 7468, 2021 | 17 | 2021 |
Formation of keto-type ceramides in palmoplantar keratoderma based on biallelic KDSR mutations in patients R Pilz, L Opálka, A Majcher, E Grimm, L Van Maldergem, S Mihalceanu, ... Human Molecular Genetics 31 (7), 1105-1114, 2022 | 15 | 2022 |
Cholesterol sulfate fluidizes the sterol fraction of the stratum corneum lipid phase and increases its permeability F Fandrei, O Engberg, L Opálka, P Jančálková, P Pullmannová, ... Journal of Lipid Research 63 (3), 2022 | 14 | 2022 |
ω-O-Acylceramides but not ω-hydroxy ceramides are required for healthy lamellar phase architecture of skin barrier lipids L Opálka, JM Meyer, V Ondrejčeková, L Svatošová, FPW Radner, ... Journal of Lipid Research 63 (6), 2022 | 12 | 2022 |
The intriguing molecular dynamics of Cer [EOS] in rigid skin barrier lipid layers requires improvement of the model F Fandrei, T Havrišák, L Opálka, O Engberg, AA Smith, P Pullmannová, ... Journal of Lipid Research 64 (5), 2023 | 9 | 2023 |