Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug AG Ramsay, AJ Johnson, AM Lee, G Gorgün, R Le Dieu, W Blum, JC Byrd, ... The Journal of clinical investigation 118 (7), 2427-2437, 2008 | 722 | 2008 |
Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma N Mimura, M Fulciniti, G Gorgun, YT Tai, D Cirstea, L Santo, Y Hu, ... Blood, The Journal of the American Society of Hematology 119 (24), 5772-5781, 2012 | 451 | 2012 |
Tumor-promoting immune-suppressive myeloid-derived suppressor cells in the multiple myeloma microenvironment in humans GT Görgün, G Whitehill, JL Anderson, T Hideshima, C Maguire, ... Blood, The Journal of the American Society of Hematology 121 (15), 2975-2987, 2013 | 423 | 2013 |
Targeting the bone marrow microenvironment in multiple myeloma Y Kawano, M Moschetta, S Manier, S Glavey, GT Görgün, AM Roccaro, ... Immunological reviews 263 (1), 160-172, 2015 | 383 | 2015 |
Chronic lymphocytic leukemia cells induce changes in gene expression of CD4 and CD8 T cells G Görgün, TAW Holderried, D Zahrieh, D Neuberg, JG Gribben The Journal of clinical investigation 115 (7), 1797-1805, 2005 | 367 | 2005 |
Lenalidomide enhances immune checkpoint blockade-induced immune response in multiple myeloma G Görgün, MK Samur, KB Cowens, S Paula, G Bianchi, JE Anderson, ... Clinical cancer research 21 (20), 4607-4618, 2015 | 315 | 2015 |
A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma G Görgün, E Calabrese, T Hideshima, J Ecsedy, G Perrone, M Mani, ... Blood, The Journal of the American Society of Hematology 115 (25), 5202-5213, 2010 | 314 | 2010 |
PI3K/p110δ is a novel therapeutic target in multiple myeloma H Ikeda, T Hideshima, M Fulciniti, G Perrone, N Miura, H Yasui, Y Okawa, ... Blood, The Journal of the American Society of Hematology 116 (9), 1460-1468, 2010 | 274 | 2010 |
Immunomodulatory effects of lenalidomide and pomalidomide on interaction of tumor and bone marrow accessory cells in multiple myeloma G Görgün, E Calabrese, E Soydan, T Hideshima, G Perrone, M Bandi, ... Blood, The Journal of the American Society of Hematology 116 (17), 3227-3237, 2010 | 252 | 2010 |
Immunologic mechanisms of extracorporeal photochemotherapy in chronic graft-versus-host disease G Gorgun, KB Miller, FM Foss Blood, The Journal of the American Society of Hematology 100 (3), 941-947, 2002 | 224 | 2002 |
Dual Inhibition of Akt/Mammalian Target of Rapamycin Pathway by Nanoparticle Albumin-Bound–Rapamycin and Perifosine Induces Antitumor Activity in Multiple … D Cirstea, T Hideshima, S Rodig, L Santo, S Pozzi, S Vallet, H Ikeda, ... Molecular cancer therapeutics 9 (4), 963-975, 2010 | 194 | 2010 |
Histone deacetylase 3 as a novel therapeutic target in multiple myeloma J Minami, R Suzuki, R Mazitschek, G Gorgun, B Ghosh, D Cirstea, Y Hu, ... Leukemia 28 (3), 680-689, 2014 | 163 | 2014 |
AT7519, A novel small molecule multi-cyclin-dependent kinase inhibitor, induces apoptosis in multiple myeloma via GSK-3β activation and RNA polymerase II inhibition L Santo, S Vallet, T Hideshima, D Cirstea, H Ikeda, S Pozzi, K Patel, ... Oncogene 29 (16), 2325-2336, 2010 | 156 | 2010 |
Ascorbic acid inhibits antitumor activity of bortezomib in vivo G Perrone, T Hideshima, H Ikeda, Y Okawa, E Calabrese, G Gorgun, ... Leukemia 23 (9), 1679-1686, 2009 | 153 | 2009 |
Eμ-TCL1 mice represent a model for immunotherapeutic reversal of chronic lymphocytic leukemia-induced T-cell dysfunction G Gorgun, AG Ramsay, TAW Holderried, D Zahrieh, R Le Dieu, F Liu, ... Proceedings of the National Academy of Sciences 106 (15), 6250-6255, 2009 | 151 | 2009 |
Aurora kinase A is a target of Wnt/β-catenin involved in multiple myeloma disease progression J Dutta-Simmons, Y Zhang, G Gorgun, M Gatt, M Mani, T Hideshima, ... Blood, The Journal of the American Society of Hematology 114 (13), 2699-2708, 2009 | 133 | 2009 |
Immunomodulatory effects of extracorporeal photochemotherapy in patients with extensive chronic graft-versus-host disease T Alcindor, G Gorgun, KB Miller, TF Roberts, K Sprague, DP Schenkein, ... Blood, The Journal of the American Society of Hematology 98 (5), 1622-1625, 2001 | 131 | 2001 |
Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma T Hideshima, J Qi, RM Paranal, W Tang, E Greenberg, N West, ... Proceedings of the National Academy of Sciences 113 (46), 13162-13167, 2016 | 128 | 2016 |
Extracorporeal photopheresis in chronic graft-versus-host disease FM Foss, G Gorgun, KB Miller Bone marrow transplantation 29 (9), 719-725, 2002 | 111 | 2002 |
Immunomodulatory effects of RXR rexinoids: modulation of high-affinity IL-2R expression enhances susceptibility to denileukin diftitox G Gorgun, F Foss Blood, The Journal of the American Society of Hematology 100 (4), 1399-1403, 2002 | 106 | 2002 |