| Mechanisms of hyperexcitability in Alzheimer’s disease hiPSC-derived neurons and cerebral organoids vs isogenic controls S Ghatak, N Dolatabadi, D Trudler, XT Zhang, Y Wu, M Mohata, ... Elife 8, e50333, 2019 | 192 | 2019 |
| α-Synuclein oligomers induce glutamate release from astrocytes and excessive extrasynaptic NMDAR activity in neurons, thus contributing to synapse loss D Trudler, S Sanz-Blasco, YS Eisele, S Ghatak, K Bodhinathan, ... Journal of Neuroscience 41 (10), 2264-2273, 2021 | 83 | 2021 |
| NitroSynapsin ameliorates hypersynchronous neural network activity in Alzheimer hiPSC models S Ghatak, N Dolatabadi, R Gao, Y Wu, H Scott, D Trudler, A Sultan, ... Molecular psychiatry 26 (10), 5751-5765, 2021 | 56 | 2021 |
| Novel therapeutic approach for excitatory/inhibitory imbalance in neurodevelopmental and neurodegenerative diseases S Ghatak, M Talantova, SR McKercher, SA Lipton Annual Review of Pharmacology and Toxicology 61 (1), 701-721, 2021 | 40 | 2021 |
| S-nitrosylated TDP-43 triggers aggregation, cell-to-cell spread, and neurotoxicity in hiPSCs and in vivo models of ALS/FTD E Pirie, C Oh, X Zhang, X Han, P Cieplak, HR Scott, AK Deal, S Ghatak, ... Proceedings of the National Academy of Sciences 118 (11), e2021368118, 2021 | 35 | 2021 |
| l‐Lactate mediates neuroprotection against ischaemia by increasing TREK1 channel expression in rat hippocampal astrocytes in vitro A Banerjee, S Ghatak, SK Sikdar Journal of Neurochemistry 138 (2), 265-281, 2016 | 27 | 2016 |
| Parkinson’s disease: what the model systems have taught us so far S Ghatak, D Trudler, N Dolatabadi, R Ambasudhan Journal of genetics 97, 729-751, 2018 | 23 | 2018 |
| Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection C Oh, T Nakamura, N Beutler, X Zhang, J Piña-Crespo, M Talantova, ... Nature chemical biology 19 (3), 275-283, 2023 | 19 | 2023 |
| Emerging hiPSC models for drug discovery in neurodegenerative diseases D Trudler, S Ghatak, SA Lipton International journal of molecular sciences 22 (15), 8196, 2021 | 18 | 2021 |
| Ischaemic concentrations of lactate increase TREK1 channel activity by interacting with a single histidine residue in the carboxy terminal domain S Ghatak, A Banerjee, SK Sikdar The Journal of physiology 594 (1), 59-81, 2016 | 15 | 2016 |
| Aberrant protein S-nitrosylation contributes to hyperexcitability-induced synaptic damage in Alzheimer’s disease: Mechanistic insights and potential therapies S Ghatak, T Nakamura, SA Lipton Frontiers in Neural Circuits 17, 1099467, 2023 | 8 | 2023 |
| Lactate modulates the intracellular pH sensitivity of human TREK1 channels S Ghatak, SK Sikdar Pflügers Archiv-European Journal of Physiology 468, 825-836, 2016 | 6 | 2016 |
| Single‐Cell Patch‐Clamp/Proteomics of Human Alzheimer's Disease iPSC‐Derived Excitatory Neurons Versus Isogenic Wild‐Type Controls Suggests Novel Causation and Therapeutic Targets S Ghatak, JK Diedrich, M Talantova, N Bhadra, H Scott, M Sharma, ... Advanced Science, 2400545, 2024 | 2 | 2024 |
| Targeted protein S-nitrosylation of ACE2 as potential treatment to prevent spread of SARS-CoV-2 infection C Oh, T Nakamura, N Beutler, X Zhang, J Piña-Crespo, M Talantova, ... bioRxiv, 2022.04. 05.487060, 2022 | 2 | 2022 |
| Prolonged exposure to lactate causes TREK1 channel clustering in rat hippocampal astrocytes S Ghatak, SK Sikdar Neuroscience Letters 821, 137613, 2024 | 1 | 2024 |
| Aberrant gliogenesis and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids D Trudler, S Ghatak, J Parker, M Talantova, T Grabauskas, SM Noveral, ... BioRxiv, 2020.11. 19.387639, 2020 | 1 | 2020 |
| Dysregulation of miRNA expression and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids D Trudler, S Ghatak, M Bula, J Parker, M Talantova, M Luevanos, S Labra, ... Molecular Psychiatry, 1-18, 2024 | | 2024 |
| Investigating expression of TREK1 & TWIK1 channels upon interaction with Aß42 oligomers in primary neuronal culture of Sprague Dawley rat brain KK Bharat, S Ghatak NISER Bhubaneswar, 2024 | | 2024 |
| Multimodal regulation of background potassium channels in alzheimer’s disease S Agrawal, S Ghatak NISER Bhubaneswar, 2024 | | 2024 |
| Ischemic Concentrations of Lactate Increase TREK1 Channel Activity and Expression S Ghatak | | 2020 |
