Predicting locations of cryptic pockets from single protein structures using the PocketMiner graph neural network A Meller, M Ward, J Borowsky, M Kshirsagar, JM Lotthammer, F Oviedo, ... Nature Communications 14 (1), 1177, 2023 | 57 | 2023 |
Direct prediction of intrinsically disordered protein conformational properties from sequence JM Lotthammer, GM Ginell, D Griffith, R Emenecker, AS Holehouse Nat Methods 21, 465–476, 2024 | 32 | 2024 |
Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains A Meller, JM Lotthammer, LG Smith, B Novak, LA Lee, CC Kuhn, ... Elife 12, e83602, 2023 | 20 | 2023 |
Functional divergence of the sarcomeric myosin, MYH7b, supports species-specific biological roles LA Lee, SK Barrick, A Meller, J Walklate, JM Lotthammer, JW Tay, ... Journal of Biological Chemistry 299 (1), 2023 | 12 | 2023 |
Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation channels APJ Giese, WH Weng, KS Kindt, HHV Chang, JS Montgomery, EM Ratzan, ... eLife 12, 2023 | 6 | 2023 |
Divergent Molecular Phenotypes in Point Mutations at the Same Residue in Beta-Myosin Heavy Chain Lead to Distinct Cardiomyopathies SJ Lehman, A Meller, SO Solieva, JM Lotthammer, L Greenberg, ... bioRxiv, 2023 | 3 | 2023 |
In Silico Electrophysiology of Inner-Ear Mechanotransduction Channel TMC1 Models S Walujkar, JM Lotthammer, CR Nisler, JC Sudar, A Ballesteros, ... bioRxiv, 2021.09. 17.460860, 2021 | 3 | 2021 |
Structuring Inner-ear Mechanotransduction D Choudhary, Y Narui, B Neel, S Walujkar, JM Lotthammer, JC Sudar, ... Biophysical Journal 118 (3), 13a, 2020 | 1 | 2020 |
Rhythmidia: a modern tool for circadian period analysis of filamentous fungi AT Keeley, JM Lotthammer, JF Pelham bioRxiv, 2024.05. 15.594281, 2024 | | 2024 |
An easy-to-use computational tool for predicting 3D properties of disordered proteins JM Lotthammer, AS Holehouse Nat Methods, 2024 | | 2024 |
Direct prediction of intermolecular interactions driven by disordered regions GM Ginell, RJ Emenecker, JM Lotthammer, ET Usher, AS Holehouse bioRxiv, 2024.06. 03.597104, 2024 | | 2024 |
Molecular mechanisms underlying CIB function in inner-ear mechanotransduction WH Weng, J Montgomery, S Walujkar, JM Lotthammer, APJ Giese, ... Biophysical Journal 121 (3), 494a, 2022 | | 2022 |
Exploring the myosin active/auto-inhibited state equilibrium by Markov state modeling JM Lotthammer, A Meller, MJ Greenberg, GR Bowman Biophysical Journal 121 (3), 260a-261a, 2022 | | 2022 |