Targeting CAL as a negative regulator of ΔF508-CFTR cell-surface expression: an RNA interference and structure-based mutagenetic approach M Wolde, A Fellows, J Cheng, A Kivenson, B Coutermarsh, L Talebian, ... Journal of Biological Chemistry 282 (11), 8099-8109, 2007 | 100 | 2007 |
Targeting specific PDZ domains of PSD-95: Structural basis for enhanced affinity and enzymatic stability of a cyclic peptide A Piserchio, GD Salinas, T Li, J Marshall, MR Spaller, DF Mierke Chemistry & biology 11 (4), 469-473, 2004 | 99 | 2004 |
Characterization of parathyroid hormone/receptor interactions: structure of the first extracellular loop A Piserchio, A Bisello, M Rosenblatt, M Chorev, DF Mierke Biochemistry 39 (28), 8153-8160, 2000 | 94 | 2000 |
NMR structural analysis of α-bungarotoxin and its complex with the principal α-neurotoxin-binding sequence on the α7 subunit of a neuronal nicotinic acetylcholine receptor L Moise, A Piserchio, VJ Basus, E Hawrot Journal of Biological Chemistry 277 (14), 12406-12417, 2002 | 81 | 2002 |
The PDZ1 domain of SAP90: characterization of structure and binding A Piserchio, M Pellegrini, S Mehta, SM Blackman, EP Garcia, J Marshall, ... Journal of Biological Chemistry 277 (9), 6967-6973, 2002 | 60 | 2002 |
Structure of tuberoinfundibular peptide of 39 residues A Piserchio, T Usdin, DF Mierke Journal of Biological Chemistry 275 (35), 27284-27290, 2000 | 60 | 2000 |
On the measurement of 15N–{1H} nuclear Overhauser effects F Ferrage, A Piserchio, D Cowburn, R Ghose Journal of Magnetic Resonance 192 (2), 302-313, 2008 | 57 | 2008 |
Solution NMR insights into docking interactions involving inactive ERK2 A Piserchio, M Warthaka, AK Devkota, TS Kaoud, S Lee, O Abramczyk, ... Biochemistry 50 (18), 3660-3672, 2011 | 47 | 2011 |
Extracellular domains of the neurokinin‐1 receptor: Structural characterization and interactions with substance P AL Ulfers, A Piserchio, DF Mierke Peptide Science: Original Research on Biomolecules 66 (5), 339-349, 2002 | 41 | 2002 |
Structural characterization of the intermolecular interactions of synapse-associated protein-97 with the NR2B subunit of N-methyl-D-aspartate receptors L Wang, A Piserchio, DF Mierke Journal of Biological Chemistry 280 (29), 26992-26996, 2005 | 38 | 2005 |
A novel class of common docking domain inhibitors that prevent ERK2 activation and substrate phosphorylation RM Sammons, NA Perry, Y Li, EJ Cho, A Piserchio, DP Zamora-Olivares, ... ACS chemical biology 14 (6), 1183-1194, 2019 | 31 | 2019 |
A model of a MAPK• substrate complex in an active conformation: A computational and experimental approach S Lee, M Warthaka, C Yan, TS Kaoud, A Piserchio, R Ghose, P Ren, ... PLoS One 6 (4), e18594, 2011 | 30 | 2011 |
Association of the cystic fibrosis transmembrane regulator with CAL: structural features and molecular dynamics A Piserchio, A Fellows, DR Madden, DF Mierke Biochemistry 44 (49), 16158-16166, 2005 | 30 | 2005 |
Structural and dynamic features of F-recruitment site driven substrate phosphorylation by ERK2 A Piserchio, V Ramakrishan, H Wang, TS Kaoud, B Arshava, K Dutta, ... Scientific reports 5 (1), 11127, 2015 | 28 | 2015 |
Local destabilization, rigid body, and fuzzy docking facilitate the phosphorylation of the transcription factor Ets-1 by the mitogen-activated protein kinase ERK2 A Piserchio, M Warthaka, TS Kaoud, K Callaway, KN Dalby, R Ghose Proceedings of the National Academy of Sciences 114 (31), E6287-E6296, 2017 | 26 | 2017 |
Modulating multi-functional ERK complexes by covalent targeting of a recruitment site in vivo TS Kaoud, WH Johnson, ND Ebelt, A Piserchio, D Zamora-Olivares, ... Nature Communications 10 (1), 5232, 2019 | 24 | 2019 |
Bradykinin B2 receptor signaling: structural and functional characterization of the C‐terminus A Piserchio, V Zelesky, J Yu, L Taylor, P Polgar, DF Mierke Peptide Science: Original Research on Biomolecules 80 (2‐3), 367-373, 2005 | 24 | 2005 |
Structural basis for the recognition of eukaryotic elongation factor 2 kinase by calmodulin K Lee, S Alphonse, A Piserchio, CDJ Tavares, DH Giles, RM Wellmann, ... Structure 24 (9), 1441-1451, 2016 | 23 | 2016 |
Optimized bacterial expression and purification of the c-Src catalytic domain for solution NMR studies A Piserchio, R Ghose, D Cowburn Journal of biomolecular NMR 44, 87-93, 2009 | 23 | 2009 |
Docking interactions of hematopoietic tyrosine phosphatase with MAP kinases ERK2 and p38α A Piserchio, DM Francis, D Koveal, KN Dalby, R Page, W Peti, R Ghose Biochemistry 51 (41), 8047-8049, 2012 | 22 | 2012 |