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Immunotherapy of non-Hodgkin’s lymphoma with a defined ratio of CD8+ and CD4+ CD19-specific chimeric antigen receptor–modified T cells CJ Turtle, LA Hanafi, C Berger, M Hudecek, B Pender, E Robinson, ... Science translational medicine 8 (355), 355ra116-355ra116, 2016 | 1074 | 2016 |
Kinetics and biomarkers of severe cytokine release syndrome after CD19 chimeric antigen receptor–modified T-cell therapy KA Hay, LA Hanafi, D Li, J Gust, WC Liles, MM Wurfel, JA López, J Chen, ... Blood, The Journal of the American Society of Hematology 130 (21), 2295-2306, 2017 | 1004 | 2017 |
Durable molecular remissions in chronic lymphocytic leukemia treated with CD19-specific chimeric antigen receptor–modified T cells after failure of ibrutinib CJ Turtle, KA Hay, LA Hanafi, D Li, S Cherian, X Chen, B Wood, ... Journal of Clinical Oncology 35 (26), 3010-3020, 2017 | 702 | 2017 |
Infectious complications of CD19-targeted chimeric antigen receptor–modified T-cell immunotherapy JA Hill, D Li, KA Hay, ML Green, S Cherian, X Chen, SR Riddell, ... Blood, The Journal of the American Society of Hematology 131 (1), 121-130, 2018 | 497 | 2018 |
Factors associated with durable EFS in adult B-cell ALL patients achieving MRD-negative CR after CD19 CAR T-cell therapy KA Hay, J Gauthier, AV Hirayama, JM Voutsinas, Q Wu, D Li, TA Gooley, ... Blood, The Journal of the American Society of Hematology 133 (15), 1652-1663, 2019 | 360 | 2019 |
Ubiquitin-independent degradation of cell-cycle inhibitors by the REGγ proteasome X Chen, LF Barton, Y Chi, BE Clurman, JM Roberts Molecular cell 26 (6), 843-852, 2007 | 327 | 2007 |
The response to lymphodepletion impacts PFS in patients with aggressive non-Hodgkin lymphoma treated with CD19 CAR T cells AV Hirayama, J Gauthier, KA Hay, JM Voutsinas, Q Wu, T Gooley, D Li, ... Blood, The Journal of the American Society of Hematology 133 (17), 1876-1887, 2019 | 299 | 2019 |
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A pathway in quiescent cells that controls p27Kip1 stability, subcellular localization, and tumor suppression A Besson, M Gurian-West, X Chen, KS Kelly-Spratt, CJ Kemp, JM Roberts Genes & development 20 (1), 47-64, 2006 | 269 | 2006 |
Multipotency of purified, transplanted globose basal cells in olfactory epithelium X Chen, H Fang, JE Schwob Journal of Comparative Neurology 469 (4), 457-474, 2004 | 250 | 2004 |
N-acetylation and ubiquitin-independent proteasomal degradation of p21Cip1 X Chen, Y Chi, A Bloecher, R Aebersold, BE Clurman, JM Roberts Molecular cell 16 (5), 839-847, 2004 | 162 | 2004 |
Diagnostic and therapeutic challenges of EBV-positive mucocutaneous ulcer: a case report and systematic review of the literature TK Roberts, X Chen, JJ Liao Experimental Hematology & Oncology 5, 1-14, 2015 | 123 | 2015 |
Monitoring minimal residual disease in acute leukemia: Technical challenges and interpretive complexities X Chen, BL Wood Blood reviews 31 (2), 63-75, 2017 | 95 | 2017 |
Safety of allogeneic hematopoietic cell transplant in adults after CD19-targeted CAR T-cell therapy M Shadman, J Gauthier, KA Hay, JM Voutsinas, F Milano, A Li, ... Blood advances 3 (20), 3062-3069, 2019 | 92 | 2019 |
Testing the importance of p27 degradation by the SCFskp2 pathway in murine models of lung and colon cancer I Timmerbeul, CM Garrett-Engele, U Kossatz, X Chen, E Firpo, ... Proceedings of the National Academy of Sciences 103 (38), 14009-14014, 2006 | 87 | 2006 |
Anti-CD19 chimeric antigen receptor-modified T Cell therapy for B cell non-Hodgkin lymphoma and chronic lymphocytic leukemia: fludarabine and cyclophosphamide lymphodepletion … CJ Turtle, C Berger, D Sommermeyer, LA Hanafi, B Pender, EM Robinson, ... Blood 126 (23), 184, 2015 | 85 | 2015 |