| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10725 | 2021 |
| A common mechanism of action for three mood-stabilizing drugs RSB Williams, L Cheng, AW Mudge, AJ Harwood Nature 417 (6886), 292-295, 2002 | 761 | 2002 |
| Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders K Augustin, A Khabbush, S Williams, S Eaton, M Orford, JH Cross, ... The Lancet Neurology 17 (1), 84-93, 2018 | 412 | 2018 |
| Loss of a prolyl oligopeptidase confers resistance to lithium by elevation of inositol (1, 4, 5) trisphosphate RSB Williams, M Eames, WJ Ryves, J Viggars, AJ Harwood The EMBO journal, 1999 | 242 | 1999 |
| Nutrition for the ageing brain: towards evidence for an optimal diet D Vauzour, M Camprubi-Robles, S Miquel-Kergoat, C Andres-Lacueva, ... Ageing research reviews 35, 222-240, 2017 | 236 | 2017 |
| Seizure control by decanoic acid through direct AMPA receptor inhibition P Chang, K Augustin, K Boddum, S Williams, M Sun, JA Terschak, ... Brain 139 (2), 431-443, 2016 | 230 | 2016 |
| Lithium therapy and signal transduction RSB Williams, AJ Harwood Trends in Pharmacological Sciences 21 (2), 61-64, 2000 | 194 | 2000 |
| Towards a molecular understanding of human diseases using Dictyostelium discoideum RSB Williams, K Boeckeler, R Gräf, A Müller-Taubenberger, Z Li, ... Trends in molecular medicine 12 (9), 415-424, 2006 | 173 | 2006 |
| Structure–function studies for the panacea, valproic acid N Terbach, RSB Williams Biochemical Society Transactions 37 (5), 1126-1132, 2009 | 169 | 2009 |
| Seizure control by ketogenic diet-associated medium chain fatty acids P Chang, N Terbach, N Plant, PE Chen, MC Walker, RSB Williams Neuropharmacology 69, 105-114, 2013 | 165 | 2013 |
| Identification of the Axin and Frat binding region of glycogen synthase kinase-3 E Fraser, N Young, R Dajani, J Franca-Koh, J Ryves, RSB Williams, ... Journal of Biological Chemistry 277 (3), 2176-2185, 2002 | 154 | 2002 |
| Cloning and characterization of a eukaryotic pantothenate kinase gene (panK) from Aspergillus nidulans RB Calder, RSB Williams, G Ramaswamy, CO Rock, E Campbell, ... Journal of Biological Chemistry 274 (4), 2014-2020, 1999 | 108 | 1999 |
| Effects of valproic acid derivatives on inositol trisphosphate depletion, teratogenicity, glycogen synthase kinase-3β inhibition, and viral replication: a screening approach … BJ Eickholt, GJ Towers, WJ Ryves, D Eikel, K Adley, LMJ Ylinen, ... Molecular pharmacology 67 (5), 1426-1433, 2005 | 103 | 2005 |
| The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium P Chang, B Orabi, RM Deranieh, M Dham, O Hoeller, JA Shimshoni, ... Disease models & mechanisms 5 (1), 115-124, 2012 | 86 | 2012 |
| Epilepsy research methods update: Understanding the causes of epileptic seizures and identifying new treatments using non-mammalian model organisms VT Cunliffe, RA Baines, CNG Giachello, WH Lin, A Morgan, M Reuber, ... Seizure 24, 44-51, 2015 | 84 | 2015 |
| A molecular cell biology of lithium R Williams, WJ Ryves, EC Dalton, B Eickholt, G Shaltiel, G Agam, ... Biochemical Society Transactions 32 (5), 799-802, 2004 | 84 | 2004 |
| Alzheimer disease research in the 21st century: past and current failures, new perspectives and funding priorities F Pistollato, EL Ohayon, A Lam, GR Langley, TJ Novak, D Pamies, ... Oncotarget 7 (26), 38999, 2016 | 81 | 2016 |
| The mood stabiliser lithium suppresses PIP3 signalling in Dictyostelium and human cells JS King, R Teo, J Ryves, JV Reddy, O Peters, B Orabi, O Hoeller, ... Disease models & mechanisms 2 (5-6), 306-312, 2009 | 77 | 2009 |
| Attenuation of phospholipid signaling provides a novel mechanism for the action of valproic acid X Xu, A Müller-Taubenberger, KE Adley, N Pawolleck, VWY Lee, ... Eukaryotic cell 6 (6), 899-906, 2007 | 77 | 2007 |
| Seizure control by derivatives of medium chain fatty acids associated with the ketogenic diet show novel branching-point structure for enhanced potency P Chang, AME Zuckermann, S Williams, AJ Close, M Cano-Jaimez, ... Journal of pharmacology and experimental therapeutics 352 (1), 43-52, 2015 | 76 | 2015 |
