| Atopic dermatitis is an IL-13–dominant disease with greater molecular heterogeneity compared to psoriasis LC Tsoi, E Rodriguez, F Degenhardt, H Baurecht, U Wehkamp, N Volks, ... Journal of Investigative Dermatology 139 (7), 1480-1489, 2019 | 400 | 2019 |
| Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa MK Sarkar, GA Hile, LC Tsoi, X Xing, J Liu, Y Liang, CC Berthier, ... Annals of the rheumatic diseases 77 (11), 1653-1664, 2018 | 209 | 2018 |
| Progression of acute-to-chronic atopic dermatitis is associated with quantitative rather than qualitative changes in cytokine responses LC Tsoi, E Rodriguez, D Stölzl, U Wehkamp, J Sun, S Gerdes, MK Sarkar, ... Journal of Allergy and Clinical Immunology 145 (5), 1406-1415, 2020 | 142 | 2020 |
| IFN-γ enhances cell-mediated cytotoxicity against keratinocytes via JAK2/STAT1 in lichen planus S Shao, LC Tsoi, MK Sarkar, X Xing, K Xue, R Uppala, CC Berthier, ... Science translational medicine 11 (511), eaav7561, 2019 | 116 | 2019 |
| “Autoinflammatory psoriasis”—genetics and biology of pustular psoriasis R Uppala, LC Tsoi, PW Harms, B Wang, AC Billi, E Maverakis, ... Cellular & molecular immunology 18 (2), 307-317, 2021 | 87 | 2021 |
| The female-biased factor VGLL3 drives cutaneous and systemic autoimmunity AC Billi, M Gharaee-Kermani, J Fullmer, LC Tsoi, BD Hill, D Gruszka, ... JCI insight 4 (8), 2019 | 58 | 2019 |
| Hypersensitive IFN responses in lupus keratinocytes reveal key mechanistic determinants in cutaneous lupus LC Tsoi, GA Hile, CC Berthier, MK Sarkar, TJ Reed, J Liu, R Uppala, ... The Journal of Immunology 202 (7), 2121-2130, 2019 | 56 | 2019 |
| NIX initiates mitochondrial fragmentation via DRP1 to drive epidermal differentiation CL Simpson, MK Tokito, R Uppala, MK Sarkar, JE Gudjonsson, ... Cell reports 34 (5), 2021 | 42 | 2021 |
| Characterization of circular RNA transcriptomes in psoriasis and atopic dermatitis reveals disease‐specific expression profiles LI Moldovan, LC Tsoi, U Ranjitha, H Hager, S Weidinger, JE Gudjonsson, ... Experimental dermatology 30 (8), 1187-1196, 2021 | 41 | 2021 |
| KLK6 expression in skin induces PAR1-mediated psoriasiform dermatitis and inflammatory joint disease AC Billi, JE Ludwig, Y Fritz, R Rozic, WR Swindell, LC Tsoi, D Gruzska, ... The Journal of clinical investigation 130 (6), 3151-3157, 2020 | 39 | 2020 |
| Phospholipase A2 enzymes represent a shared pathogenic pathway in psoriasis and pityriasis rubra pilaris S Shao, J Chen, WR Swindell, LC Tsoi, X Xing, F Ma, R Uppala, ... JCI insight 6 (20), 2021 | 38 | 2021 |
| IL-27 signaling activates skin cells to induce innate antiviral proteins and protects against Zika virus infection JT Kwock, C Handfield, J Suwanpradid, P Hoang, MJ McFadden, ... Science Advances 6 (14), eaay3245, 2020 | 38 | 2020 |
| Noninvasive tape-stripping with high-resolution RNA profiling effectively captures a preinflammatory state in nonlesional psoriatic skin LC Tsoi, X Xing, E Xing, R Wasikowski, S Shao, C Zeng, O Plazyo, ... Journal of Investigative Dermatology 142 (6), 1587-1596. e2, 2022 | 15 | 2022 |
| Biogeographic and disease-specific alterations in epidermal lipid composition and single-cell analysis of acral keratinocytes AA Merleev, ST Le, C Alexanian, A Toussi, Y Xie, AI Marusina, ... JCI insight 7 (16), 2022 | 13 | 2022 |
| Cytokine responses in nonlesional psoriatic skin as clinical predictor to anti-TNF agents LC Tsoi, MT Patrick, S Shuai, MK Sarkar, S Chi, B Ruffino, AC Billi, X Xing, ... Journal of Allergy and Clinical Immunology 149 (2), 640-649. e5, 2022 | 13 | 2022 |
| IRAK2 has a critical role in promoting feed-forward amplification of epidermal inflammatory responses S Shao, LC Tsoi, WR Swindell, J Chen, R Uppala, AC Billi, X Xing, ... Journal of Investigative Dermatology 141 (10), 2436-2448, 2021 | 12 | 2021 |
| Keratinocytes sense and eliminate CRISPR DNA through STING/IFN-κ activation and APOBEC3G induction MK Sarkar, R Uppala, C Zeng, AC Billi, LC Tsoi, A Kidder, X Xing, ... The Journal of clinical investigation 133 (9), 2023 | 7 | 2023 |
| Single-cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa KR van Straalen, F Ma, PS Tsou, O Plazyo, M Gharaee-Kermani, ... The Journal of Clinical Investigation 134 (3), 2024 | 3 | 2024 |
| Suppression of TCF4 promotes a ZC3H12A-mediated self-sustaining inflammatory feedback cycle involving IL-17RA/IL-17RE epidermal signaling Y Jiang, D Gruszka, C Zeng, WR Swindell, C Gaskill, C Sorensen, ... JCI insight 9 (8), 2024 | 1 | 2024 |
| HERC6 regulates STING activity in a sex-biased manner through modulation of LATS2/VGLL3 Hippo signaling R Uppala, MK Sarkar, KZ Young, F Ma, P Vemulapalli, R Wasikowski, ... Iscience 27 (2), 2024 | 1 | 2024 |
