Glucokinase and molecular aspects of liver glycogen metabolism L Agius Biochemical Journal 414 (1), 1-18, 2008 | 472 | 2008 |
The biochemistry of diabetes. R Taylor, L Agius Biochemical Journal 250 (3), 625, 1988 | 256 | 1988 |
New hepatic targets for glycaemic control in diabetes L Agius Best Practice & Research Clinical Endocrinology & Metabolism 21 (4), 587-605, 2007 | 202 | 2007 |
Evidence for a role of glucose-induced translocation of glucokinase in the control of hepatic glycogen synthesis L Agius, M Peak, CB Newgard, AM Gomez-Foix, JJ Guinovart Journal of Biological Chemistry 271 (48), 30479-30486, 1996 | 191 | 1996 |
Stimulation of hepatocyte glucose metabolism by novel small molecule glucokinase activators KJ Brocklehurst, VA Payne, RA Davies, D Carroll, HL Vertigan, ... Diabetes 53 (3), 535-541, 2004 | 190 | 2004 |
Role of glycogen phosphorylase in liver glycogen metabolism L Agius Molecular aspects of medicine 46, 34-45, 2015 | 180 | 2015 |
Intracellular binding of glucokinase in hepatocytes and translocation by glucose, fructose and insulin L Agius, M Peak Biochemical Journal 296 (3), 785-796, 1993 | 176 | 1993 |
The role of the regulatory protein of glucokinase in the glucose sensory mechanism of the hepatocyte N De La Iglesia, M Mukhtar, J Seoane, JJ Guinovart, L Agius Journal of Biological Chemistry 275 (14), 10597-10603, 2000 | 142 | 2000 |
Leptin enhances glycogen storage in hepatocytes by inhibition of phosphorylase and exerts an additive effect with insulin. S Aiston, L Agius Diabetes 48 (1), 15-20, 1999 | 141 | 1999 |
Blood glucose, lactate, pyruvate, glycerol, 3-hydroxybutyrate and acetoacetate measurements in man using a centrifugal analyser with a fluorimetric attachment J Harrison, AW Hodson, AW Skillen, R Stappenbeck, L Agius, K Alberti Walter de Gruyter, Berlin/New York 26 (3), 141-146, 1988 | 132 | 1988 |
Fructose 2, 6-bisphosphate is essential for glucose-regulated gene transcription of glucose-6-phosphatase and other ChREBP target genes in hepatocytes C Arden, SJ Tudhope, JL Petrie, ZH Al-Oanzi, KS Cullen, AJ Lange, ... Biochemical Journal 443 (1), 111-123, 2012 | 126 | 2012 |
Lipogenesis in interscapular brown adipose tissue of virgin, pregnant and lactating rats. The effects of intragastric feeding. L Agius, DH Williamson Biochemical Journal 190 (2), 477, 1980 | 125 | 1980 |
Alterations in the rate of lipogenesis in vivo in maternal liver and adipose tissue on premature weaning of lactating rats: a possible regulatory role of prolactin. L Agius, AM Robinson, JR Girard, DH Williamson Biochemical Journal 180 (3), 689, 1979 | 123 | 1979 |
Glucose-6-phosphatase overexpression lowers glucose 6-phosphate and inhibits glycogen synthesis and glycolysis in hepatocytes without affecting glucokinase translocation … S Aiston, KY Trinh, AJ Lange, CB Newgard, L Agius Journal of Biological Chemistry 274 (35), 24559-24566, 1999 | 111 | 1999 |
Metabolic effects of suppression of nonesterified fatty acid levels with acipimox in obese NIDDM subjects GR Fulcher, M Walker, C Catalano, L Agius, K Alberti Diabetes 41 (11), 1400-1408, 1992 | 98 | 1992 |
Regulation of glycogen synthesis from glucose and gluconeogenic precursors by insulin in periportal and perivenous rat hepatocytes L Agius, M Peak, K Alberti Biochemical Journal 266 (1), 91-102, 1990 | 97 | 1990 |
The metformin mechanism on gluconeogenesis and AMPK activation: the metabolite perspective L Agius, BE Ford, SS Chachra International journal of molecular sciences 21 (9), 3240, 2020 | 96 | 2020 |
Hepatic glycogen synthesis is highly sensitive to phosphorylase activity: evidence from metabolic control analysis S Aiston, L Hampson, AM Gómez-Foix, JJ Guinovart, L Agius Journal of Biological Chemistry 276 (26), 23858-23866, 2001 | 95 | 2001 |
Regulation of glycogen synthesis and glycolysis by insulin, pH and cell volume. Interactions between swelling and alkalinization in mediating the effects of insulin M Peak, M Al-Habori, L Agius Biochemical Journal 282 (3), 797-805, 1992 | 95 | 1992 |
Glucose 6-phosphate regulates hepatic glycogenolysis through inactivation of phosphorylase S Aiston, B Andersen, L Agius Diabetes 52 (6), 1333-1339, 2003 | 93 | 2003 |