Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent-and AIF-mediated cell death A Seiler, M Schneider, H Förster, S Roth, EK Wirth, C Culmsee, N Plesnila, ... Cell metabolism 8 (3), 237-248, 2008 | 1329 | 2008 |
Selenium utilization by GPX4 is required to prevent hydroperoxide-induced ferroptosis I Ingold, C Berndt, S Schmitt, S Doll, G Poschmann, K Buday, A Roveri, ... Cell 172 (3), 409-422. e21, 2018 | 1142 | 2018 |
Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues. L Schomburg, U Schweizer, B Holtmann, L Flohé, M Sendtner, J Köhrle Biochemical Journal 370 (Pt 2), 397, 2003 | 506 | 2003 |
Selenium and brain function: a poorly recognized liaison U Schweizer, AU Bräuer, J Köhrle, R Nitsch, NE Savaskan Brain Research Reviews 45 (3), 164-178, 2004 | 441 | 2004 |
Hierarchical regulation of selenoprotein expression and sex-specific effects of selenium L Schomburg, U Schweizer Biochimica et Biophysica Acta (BBA)-General Subjects 1790 (11), 1453-1462, 2009 | 283 | 2009 |
Selenium and selenoproteins in mammals: extraordinary, essential, enigmatic L Schomburg, U Schweizer, J Köhrle Cellular and Molecular Life Sciences CMLS 61, 1988-1995, 2004 | 272 | 2004 |
Selenoprotein gene nomenclature VN Gladyshev, ES Arnér, MJ Berry, R Brigelius-Flohé, EA Bruford, ... Journal of Biological Chemistry 291 (46), 24036-24040, 2016 | 261 | 2016 |
Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration BA Carlson, R Tobe, E Yefremova, PA Tsuji, VJ Hoffmann, U Schweizer, ... Redox biology 9, 22-31, 2016 | 260 | 2016 |
Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration EK Wirth, M Conrad, J Winterer, C Wozny, BA Carlson, S Roth, D Schmitz, ... The FASEB Journal 24 (3), 844, 2010 | 252 | 2010 |
Conditional gene ablation of Stat3 reveals differential signaling requirements for survival of motoneurons during development and after nerve injury in the adult U Schweizer, J Gunnersen, C Karch, S Wiese, B Holtmann, K Takeda, ... The Journal of cell biology 156 (2), 287-298, 2002 | 247 | 2002 |
Hepatically derived selenoprotein P is a key factor for kidney but not for brain selenium supply U Schweizer, F STRECKFUß, P Pelt, BA Carlson, DL Hatfield, J Köhrle, ... Biochemical Journal 386 (2), 221-226, 2005 | 235 | 2005 |
Chemistry and biology in the biosynthesis and action of thyroid hormones S Mondal, K Raja, U Schweizer, G Mugesh Angewandte Chemie International Edition 55 (27), 7606-7630, 2016 | 234 | 2016 |
Neuronal 3′, 3, 5-triiodothyronine (T3) uptake and behavioral phenotype of mice deficient in Mct8, the neuronal T3 transporter mutated in Allan–Herndon–Dudley syndrome EK Wirth, S Roth, C Blechschmidt, SM Hölter, L Becker, I Racz, A Zimmer, ... Journal of Neuroscience 29 (30), 9439-9449, 2009 | 208 | 2009 |
Comparative analysis of selenocysteine machinery and selenoproteome gene expression in mouse brain identifies neurons as key functional sites of selenium in mammals Y Zhang, Y Zhou, U Schweizer, NE Savaskan, D Hua, J Kipnis, ... Journal of Biological Chemistry 283 (4), 2427-2438, 2008 | 187 | 2008 |
Developmental motoneuron cell death and neurotrophic factors M Sendtner, G Pei, M Beck, U Schweizer, S Wiese Cell and tissue research 301, 71-84, 2000 | 182 | 2000 |
Hepatic selenoprotein P (SePP) expression restores selenium transport and prevents infertility and motor-incoordination in Sepp-knockout mice K Renko, M Werner, I Renner-Müller, TG Cooper, CH Yeung, ... Biochemical Journal 409 (3), 741-749, 2008 | 181 | 2008 |
Down‐regulation of the hepatic selenoprotein biosynthesis machinery impairs selenium metabolism during the acute phase response in mice K Renko, PJ Hofmann, M Stoedter, B Hollenbach, T Behrends, J Köhrle, ... The FASEB Journal 23 (6), 1758-1765, 2009 | 164 | 2009 |
Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells R Götz, S Wiese, S Takayama, GC Camarero, W Rossoll, U Schweizer, ... Nature neuroscience 8 (9), 1169-1178, 2005 | 155 | 2005 |
Circulating adipokines and the protective effects of hyperinsulinemia in inflammatory bowel disease L Valentini, EK Wirth, U Schweizer, S Hengstermann, L Schaper, ... Nutrition 25 (2), 172-181, 2009 | 138 | 2009 |
The neurobiology of selenium: lessons from transgenic mice U Schweizer, L Schomburg, NE Savaskan The Journal of nutrition 134 (4), 707-710, 2004 | 133 | 2004 |