Mapping genomic loci implicates genes and synaptic biology in schizophrenia V Trubetskoy, AF Pardiñas, T Qi, G Panagiotaropoulou, S Awasthi, ... Nature 604 (7906), 502-508, 2022 | 1480 | 2022 |
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... Nature genetics 53 (9), 1300-1310, 2021 | 952 | 2021 |
Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals L Folkersen, S Gustafsson, Q Wang, DH Hansen, ÅK Hedman, A Schork, ... Nature metabolism 2 (10), 1135-1148, 2020 | 451 | 2020 |
A resource-efficient tool for mixed model association analysis of large-scale data L Jiang, Z Zheng, T Qi, KE Kemper, NR Wray, PM Visscher, J Yang Nature genetics 51 (12), 1749-1755, 2019 | 429 | 2019 |
Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood T Qi, Y Wu, J Zeng, F Zhang, A Xue, L Jiang, Z Zhu, K Kemper, L Yengo, ... Nature communications 9 (1), 2282, 2018 | 346 | 2018 |
Integrative analysis of omics summary data reveals putative mechanisms underlying complex traits Y Wu, J Zeng, F Zhang, Z Zhu, T Qi, Z Zheng, LR Lloyd-Jones, RE Marioni, ... Nature communications 9 (1), 1-14, 2018 | 316 | 2018 |
Genomic variation associated with local adaptation of weedy rice during de-domestication J Qiu, Y Zhou, L Mao, C Ye, W Wang, J Zhang, Y Yu, F Fu, Y Wang, ... Nature communications 8 (1), 15323, 2017 | 153 | 2017 |
OSCA: a tool for omic-data-based complex trait analysis F Zhang, W Chen, Z Zhu, Q Zhang, MF Nabais, T Qi, IJ Deary, NR Wray, ... Genome biology 20, 1-13, 2019 | 137 | 2019 |
Analysis of DNA methylation associates the cystine–glutamate antiporter SLC7A11 with risk of Parkinson’s disease CL Vallerga, F Zhang, J Fowdar, AF McRae, T Qi, MF Nabais, Q Zhang, ... Nature communications 11 (1), 1238, 2020 | 117 | 2020 |
GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19 E Pairo-Castineira, K Rawlik, AD Bretherick, T Qi, Y Wu, I Nassiri, ... Nature 617 (7962), 764-768, 2023 | 89 | 2023 |
Genetic control of RNA splicing and its distinct role in complex trait variation T Qi, Y Wu, H Fang, F Zhang, S Liu, J Zeng, J Yang Nature genetics 54 (9), 1355-1363, 2022 | 86 | 2022 |
Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders EM Byrne, Z Zhu, T Qi, NG Skene, J Bryois, AF Pardinas, E Stahl, ... Molecular psychiatry 26 (6), 2070-2081, 2021 | 62* | 2021 |
Mixed linear model approaches of association mapping for complex traits based on omics variants FT Zhang, ZH Zhu, XR Tong, ZX Zhu, T Qi, J Zhu Scientific reports 5 (1), 10298, 2015 | 48 | 2015 |
Tissue specific regulation of transcription in endometrium and association with disease S Mortlock, RI Kendarsari, JN Fung, G Gibson, F Yang, R Restuadi, ... Human Reproduction 35 (2), 377-393, 2020 | 46 | 2020 |
Improved analyses of GWAS summary statistics by reducing data heterogeneity and errors W Chen, Y Wu, Z Zheng, T Qi, PM Visscher, Z Zhu, J Yang Nature Communications 12 (1), 7117, 2021 | 45 | 2021 |
Genetic regulation of methylation in human endometrium and blood and gene targets for reproductive diseases S Mortlock, R Restuadi, R Levien, JE Girling, SJ Holdsworth-Carson, ... Clinical epigenetics 11, 1-19, 2019 | 29 | 2019 |
Joint analysis of GWAS and multi-omics QTL summary statistics reveals a large fraction of GWAS signals shared with molecular phenotypes Y Wu, T Qi, NR Wray, PM Visscher, J Zeng, J Yang Cell Genomics 3 (8), 2023 | 21 | 2023 |
Multivariate dimensionality reduction approaches to identify gene-gene and gene-environment interactions underlying multiple complex traits HM Xu, XW Sun, T Qi, WY Lin, N Liu, XY Lou PLoS One 9 (9), e108103, 2014 | 20 | 2014 |
Tumor mutational burden is polygenic and genetically associated with complex traits and diseases X Sun, A Xue, T Qi, D Chen, D Shi, Y Wu, Z Zheng, J Zeng, J Yang Cancer Research 81 (5), 1230-1239, 2021 | 17 | 2021 |
IRX3 is a genetic modifier for birth weight, adolescent obesity and transaminase metabolism C Liu, C Chu, J Zhang, D Wu, D Xu, P Li, Y Chen, B Liu, L Pei, L Zhang, ... Pediatric obesity 13 (3), 141-148, 2018 | 17 | 2018 |