Microbial imidazole propionate affects responses to metformin through p38γ-dependent inhibitory AMPK phosphorylation A Koh, L Mannerås-Holm, NO Yunn, PM Nilsson, SH Ryu, A Molinaro, ... Cell metabolism 32 (4), 643-653. e4, 2020 | 99 | 2020 |
Agonistic aptamer to the insulin receptor leads to biased signaling and functional selectivity through allosteric modulation NO Yunn, A Koh, S Han, JH Lim, S Park, J Lee, E Kim, SK Jang, ... Nucleic acids research 43 (16), 7688-7701, 2015 | 63 | 2015 |
PI3K-C2α knockdown results in rerouting of insulin signaling and pancreatic beta cell proliferation B Leibiger, T Moede, M Paschen, NO Yunn, JH Lim, SH Ryu, T Pereira, ... Cell Reports 13 (1), 15-22, 2015 | 37 | 2015 |
Formation of cellular close-ended tunneling nanotubes through mechanical deformation M Chang, O Lee, G Bu, J Oh, NO Yunn, SH Ryu, HB Kwon, ... Science Advances 8 (13), eabj3995, 2022 | 25 | 2022 |
Aptamer-based single-molecule imaging of insulin receptors in living cells M Chang, M Kwon, S Kim, NO Yunn, D Kim, SH Ryu, JB Lee Journal of biomedical optics 19 (5), 051204-051204, 2014 | 24 | 2014 |
Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures J Kim, NO Yunn, M Park, J Kim, S Park, Y Kim, J Noh, SH Ryu, Y Cho Nature Communications 13 (1), 6500, 2022 | 13 | 2022 |
A hotspot for enhancing insulin receptor activation revealed by a conformation-specific allosteric aptamer NO Yunn, M Park, S Park, J Lee, J Noh, E Shin, SH Ryu Nucleic Acids Research 49 (2), 700-712, 2021 | 12 | 2021 |
Mechanistic understanding of insulin receptor modulation: Implications for the development of anti-diabetic drugs NO Yunn, J Kim, Y Kim, I Leibiger, PO Berggren, SH Ryu Pharmacology & therapeutics 185, 86-98, 2018 | 12 | 2018 |
A stepwise activation model for the insulin receptor NO Yunn, J Kim, SH Ryu, Y Cho Experimental & Molecular Medicine 55 (10), 2147-2161, 2023 | 7 | 2023 |
An aptamer agonist of the insulin receptor acts as a positive or negative allosteric modulator, depending on its concentration NO Yunn, J Lee, HS Lee, EJ Oh, M Park, S Park, SY Jin, E Shin, J Lee, ... Experimental & Molecular Medicine 54 (4), 531-541, 2022 | 6 | 2022 |
Regulation of BRCA1 stability through the tandem UBX domains of isoleucyl-tRNA synthetase 1 S Chung, MS Kang, DS Alimbetov, GI Mun, NO Yunn, Y Kim, BG Kim, ... Nature communications 13 (1), 6732, 2022 | 4 | 2022 |