关注
Reuben A. Saunders
Reuben A. Saunders
Whitehead Institute
在 wi.mit.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike
M Schoof*, B Faust*, RA Saunders*, S Sangwan*, V Rezelj*, N Hoppe, ...
Science 370 (6523), 1473-1479, 2020
4062020
Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq
JM Replogle*, RA Saunders*, AN Pogson, JA Hussmann, A Lenail, ...
Cell 185 (14), 2559-2575.e28, 2022
3662022
A J-Protein Co-chaperone Recruits BiP to Monomerize IRE1 and Repress the Unfolded Protein Response
N Amin-Wetzel*, RA Saunders*, MJ Kamphuis, C Rato, S Preissler, ...
Cell 171 (7), 1625-1637. e13, 2017
2472017
Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs
M Jost*, DA Santos*, RA Saunders, MA Horlbeck, JS Hawkins, SM Scaria, ...
Nature biotechnology 38 (3), 355-364, 2020
1432020
Porous titanium bases for osteochondral tissue engineering
AB Nover, SL Lee, MS Georgescu, DR Howard, RA Saunders, TY William, ...
Acta biomaterialia 27, 286-293, 2015
482015
Multistep substrate binding and engagement by the AAA+ ClpXP protease
RA Saunders, BM Stinson, TA Baker, RT Sauer
Proceedings of the National Academy of Sciences 117 (45), 28005-28013, 2020
202020
Repeat-associated non-AUG translation induces cytoplasmic aggregation of CAG repeat-containing RNAs
MR Das, Y Chang, R Anderson, RA Saunders, N Zhang, CP Tomberlin, ...
Proceedings of the National Academy of Sciences 120 (3), e2215071120, 2023
152023
Comparative landscape of genetic dependencies in human and chimpanzee stem cells
R She, T Fair, NK Schaefer, RA Saunders, BJ Pavlovic, JS Weissman, ...
Cell 186 (14), 2977-2994. e23, 2023
122023
Triaging of α-helical proteins to the mitochondrial outer membrane by distinct chaperone machinery based on substrate topology
G Muthukumar, TA Stevens, AJ Inglis, TK Esantsi, RA Saunders, F Schulte, ...
Molecular Cell 84 (6), 1101-1119. e9, 2024
22024
A platform for multimodal in vivo pooled genetic screens reveals regulators of liver function
RA Saunders, WE Allen, X Pan, J Sandhu, J Lu, TK Lau, K Smolyar, ...
bioRxiv, 2024.11. 18.624217, 2024
2024
POOLED GENETIC SCREENS WITH RICH READOUTS AT SCALE AND IN VIVO
RA Saunders
UCSF, 2024
2024
Sars-cov2 neutralizing single domain antibody constructs
P Walter, A Manglik, M Schoof, B Faust, N Hoppe, R Saunders, ...
US Patent App. 17/998,605, 2023
2023
Control of mammalian gene dosage using crispr
J Weissman, M Jost, MA Horlbeck, D Santos, R Saunders
US Patent App. 17/584,176, 2022
2022
Flanking sequences regulate the toxicity, non-ATG translation, and aggregation of RNA with tandem CAG Repeats
MR Das, Y Chang, R Saunders, N Zhang, C Tomberlin, RD Vale, A Jain
bioRxiv, 2021.08. 30.458106, 2021
2021
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