| AlphaFold accelerates artificial intelligence powered drug discovery: efficient discovery of a novel CDK20 small molecule inhibitor F Ren, X Ding, M Zheng, M Korzinkin, X Cai, W Zhu, A Mantsyzov, ... Chemical science 14 (6), 1443-1452, 2023 | 121 | 2023 |
| AI-powered therapeutic target discovery FW Pun, IV Ozerov, A Zhavoronkov Trends in pharmacological sciences, 2023 | 69 | 2023 |
| Imprinting in the schizophrenia candidate gene GABRB2 encoding GABAA receptor β2 subunit FW Pun, C Zhao, WS Lo, SK Ng, SY Tsang, V Nimgaonkar, WS Chung, ... Molecular psychiatry 16 (5), 557-568, 2011 | 67 | 2011 |
| Two isoforms of GABAA receptor β2 subunit with different electrophysiological properties: differential expression and genotypical correlations in schizophrenia C Zhao, Z Xu, J Chen, Z Yu, KL Tong, WS Lo, FW Pun, SK Ng, SY Tsang, ... Molecular psychiatry 11 (12), 1092-1105, 2006 | 66 | 2006 |
| GABRB2 association with schizophrenia: commonalities and differences between ethnic groups and clinical subtypes WS Lo, M Harano, M Gawlik, Z Yu, J Chen, FW Pun, KL Tong, C Zhao, ... Biological psychiatry 61 (5), 653-660, 2007 | 60 | 2007 |
| Positive Selection within the Schizophrenia-Associated GABAA Receptor β2 Gene WS Lo, Z Xu, Z Yu, FW Pun, SK Ng, J Chen, KL Tong, C Zhao, X Xu, ... PLoS One 2 (5), e462, 2007 | 51 | 2007 |
| Alternative-Splicing in the Exon-10 Region of GABAA Receptor β2 Subunit Gene: Relationships between Novel Isoforms and Psychotic Disorders C Zhao, Z Xu, F Wang, J Chen, SK Ng, PW Wong, Z Yu, FW Pun, L Ren, ... PloS one 4 (9), e6977, 2009 | 46 | 2009 |
| Hallmarks of aging-based dual-purpose disease and age-associated targets predicted using PandaOmics AI-powered discovery engine FW Pun, GHD Leung, HW Leung, BHM Liu, X Long, IV Ozerov, J Wang, ... Aging (Albany NY) 14 (6), 2475, 2022 | 45 | 2022 |
| Identification of therapeutic targets for amyotrophic lateral sclerosis using PandaOmics–an AI-enabled biological target discovery platform FW Pun, BHM Liu, X Long, HW Leung, GHD Leung, QT Mewborne, J Gao, ... Frontiers in aging neuroscience 14, 914017, 2022 | 40 | 2022 |
| Social Cognitive Role of Schizophrenia Candidate Gene GABRB2 SY Tsang, S Zhong, L Mei, J Chen, SK Ng, FW Pun, C Zhao, B Jing, ... PloS one 8 (4), e62322, 2013 | 38 | 2013 |
| Epigenetic regulation on GABRB2 isoforms expression: developmental variations and disruptions in psychotic disorders C Zhao, F Wang, FW Pun, L Mei, L Ren, Z Yu, SK Ng, J Chen, SY Tsang, ... Schizophrenia research 134 (2-3), 260-266, 2012 | 36 | 2012 |
| GABRB2 in schizophrenia and bipolar disorder: disease association, gene expression and clinical correlations J Chen, SY Tsang, CY Zhao, FW Pun, Z Yu, L Mei, WS Lo, S Fang, H Liu, ... Biochemical Society Transactions 37 (6), 1415-1418, 2009 | 35 | 2009 |
| AluScan: a method for genome-wide scanning of sequence and structure variations in the human genome L Mei, X Ding, SY Tsang, FW Pun, SK Ng, J Yang, C Zhao, D Li, W Wan, ... BMC genomics 12, 1-9, 2011 | 28 | 2011 |
| A Recombination Hotspot in a Schizophrenia-Associated Region of GABRB2 SK Ng, WS Lo, FW Pun, C Zhao, Z Yu, J Chen, KL Tong, Z Xu, SY Tsang, ... PloS one 5 (3), e9547, 2010 | 28 | 2010 |
| Massive interstitial copy-neutral loss-of-heterozygosity as evidence for cancer being a disease of the DNA-damage response Y Kumar, J Yang, T Hu, L Chen, Z Xu, L Xu, XX Hu, G Tang, JM Wang, ... BMC medical genomics 8, 1-21, 2015 | 22 | 2015 |
| A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models F Ren, A Aliper, J Chen, H Zhao, S Rao, C Kuppe, IV Ozerov, M Zhang, ... Nature Biotechnology, 1-13, 2024 | 15 | 2024 |
| GABRB2 Haplotype Association with Heroin Dependence in Chinese Population YS Kim, M Yang, WK Mat, SY Tsang, Z Su, X Jiang, SK Ng, S Liu, T Hu, ... PLoS One 10 (11), e0142049, 2015 | 14 | 2015 |
| Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for aging and age-related disease target discovery A Urban, D Sidorenko, D Zagirova, E Kozlova, A Kalashnikov, S Pushkov, ... Aging (Albany NY) 15 (11), 4649, 2023 | 8 | 2023 |
| High-confidence cancer patient stratification through multiomics investigation of DNA repair disorders GV Mkrtchyan, A Veviorskiy, E Izumchenko, A Shneyderman, FW Pun, ... Cell Death & Disease 13 (11), 999, 2022 | 7 | 2022 |
| Glioma Association and Balancing Selection of ZFPM2 SY Tsang, L Mei, W Wan, J Li, Y Li, C Zhao, X Ding, FW Pun, X Hu, ... PLoS One 10 (7), e0133003, 2015 | 7 | 2015 |
