Covalent histone modifications—miswritten, misinterpreted and mis-erased in human cancers P Chi, CD Allis, GG Wang Nature reviews cancer 10 (7), 457-469, 2010 | 1293 | 2010 |
Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6 H Häcker, V Redecke, B Blagoev, I Kratchmarova, LC Hsu, GG Wang, ... Nature 439 (7073), 204-207, 2006 | 1244 | 2006 |
Chromatin remodeling and cancer, Part I: Covalent histone modifications GG Wang, CD Allis, P Chi Trends in molecular medicine 13 (9), 363-372, 2007 | 538 | 2007 |
An orally bioavailable chemical probe of the lysine methyltransferases EZH2 and EZH1 KD Konze, A Ma, F Li, D Barsyte-Lovejoy, T Parton, CJ MacNevin, F Liu, ... ACS chemical biology 8 (6), 1324-1334, 2013 | 486 | 2013 |
NUP98–NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis GG Wang, L Cai, MP Pasillas, MP Kamps Nature cell biology 9 (7), 804-812, 2007 | 475 | 2007 |
Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger GG Wang, J Song, Z Wang, HL Dormann, F Casadio, H Li, JL Luo, ... Nature 459 (7248), 847-851, 2009 | 470 | 2009 |
Quantitative production of macrophages or neutrophils ex vivo using conditional Hoxb8 GG Wang, KR Calvo, MP Pasillas, DB Sykes, H Häcker, MP Kamps Nature methods 3 (4), 287-293, 2006 | 411 | 2006 |
Chromatin remodeling and cancer, Part II: ATP-dependent chromatin remodeling GG Wang, CD Allis, P Chi Trends in molecular medicine 13 (9), 373-380, 2007 | 333 | 2007 |
An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting L Cai, SB Rothbart, R Lu, B Xu, WY Chen, A Tripathy, S Rockowitz, ... Molecular cell 49 (3), 571-582, 2013 | 272 | 2013 |
Structural basis for DNMT3A-mediated de novo DNA methylation ZM Zhang, R Lu, P Wang, Y Yu, D Chen, L Gao, S Liu, D Ji, SB Rothbart, ... Nature 554 (7692), 387-391, 2018 | 257 | 2018 |
PHD fingers in human diseases: disorders arising from misinterpreting epigenetic marks LA Baker, CD Allis, GG Wang Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 647 (1 …, 2008 | 256 | 2008 |
Multiple interactions recruit MLL1 and MLL1 fusion proteins to the HOXA9 locus in leukemogenesis TA Milne, J Kim, GG Wang, SC Stadler, V Basrur, SJ Whitcomb, Z Wang, ... Molecular cell 38 (6), 853-863, 2010 | 249 | 2010 |
Phase separation drives aberrant chromatin looping and cancer development JH Ahn, ES Davis, TA Daugird, S Zhao, IY Quiroga, H Uryu, J Li, AJ Storey, ... Nature 595 (7868), 591-595, 2021 | 247 | 2021 |
Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression Z Wang, J Song, TA Milne, GG Wang, H Li, CD Allis, DJ Patel Cell 141 (7), 1183-1194, 2010 | 240 | 2010 |
Selective inhibition of EZH2 and EZH1 enzymatic activity by a small molecule suppresses MLL-rearranged leukemia B Xu, DM On, A Ma, T Parton, KD Konze, SG Pattenden, DF Allison, L Cai, ... Blood, The Journal of the American Society of Hematology 125 (2), 346-357, 2015 | 234 | 2015 |
The language of chromatin modification in human cancers S Zhao, CD Allis, GG Wang Nature Reviews Cancer 21 (7), 413-430, 2021 | 233 | 2021 |
Bmi1 is a key epigenetic barrier to direct cardiac reprogramming Y Zhou, L Wang, HR Vaseghi, Z Liu, R Lu, S Alimohamadi, C Yin, JD Fu, ... Cell stem cell 18 (3), 382-395, 2016 | 217 | 2016 |
Tudor: a versatile family of histone methylation ‘readers’ R Lu, GG Wang Trends in biochemical sciences 38 (11), 546-555, 2013 | 185 | 2013 |
Lens epithelium-derived growth factor fusion proteins redirect HIV-1 DNA integration AL Ferris, X Wu, CM Hughes, C Stewart, SJ Smith, TA Milne, GG Wang, ... Proceedings of the National Academy of Sciences 107 (7), 3135-3140, 2010 | 172 | 2010 |
Epigenetic perturbations by Arg882-mutated DNMT3A potentiate aberrant stem cell gene-expression program and acute leukemia development R Lu, P Wang, T Parton, Y Zhou, K Chrysovergis, S Rockowitz, WY Chen, ... Cancer cell 30 (1), 92-107, 2016 | 158 | 2016 |