Serotonin receptor 2B signaling with interstitial cell activation and leaflet remodeling in degenerative mitral regurgitation KH Driesbaugh, E Branchetti, JB Grau, SJ Keeney, K Glass, MA Oyama, ... Journal of molecular and cellular cardiology 115, 94-103, 2018 | 35 | 2018 |
Iron imaging in myocardial infarction reperfusion injury BF Moon, SK Iyer, E Hwuang, MP Solomon, AT Hall, R Kumar, ... Nature communications 11 (1), 3273, 2020 | 32 | 2020 |
Glycation and serum albumin infiltration contribute to the structural degeneration of bioprosthetic heart valves A Frasca, Y Xue, AP Kossar, S Keeney, C Rock, A Zakharchenko, ... Basic to Translational Science 5 (8), 755-766, 2020 | 27 | 2020 |
Decreased serotonin transporter activity in the mitral valve contributes to progression of degenerative mitral regurgitation E Castillero, E Fitzpatrick, SJ Keeney, AM D’Angelo, BB Pressly, ... Science translational medicine 15 (677), eadc9606, 2023 | 7 | 2023 |
Inhibition of advanced glycation end product formation and serum protein infiltration in bioprosthetic heart valve leaflets: Investigations of anti-glycation agents and … A Zakharchenko, CA Rock, TE Thomas, S Keeney, EJ Hall, H Takano, ... Biomaterials 289, 121782, 2022 | 7 | 2022 |
Poly-2-methyl-2-oxazoline–modified bioprosthetic heart valve leaflets have enhanced biocompatibility and resist structural degeneration A Zakharchenko, Y Xue, S Keeney, CA Rock, IS Alferiev, SJ Stachelek, ... Proceedings of the National Academy of Sciences 119 (6), e2120694119, 2022 | 6 | 2022 |
Magnetic susceptibility and R2* of myocardial reperfusion injury at 3T and 7T BF Moon, SK Iyer, NJ Josselyn, E Hwuang, S Swago, SJ Keeney, ... Magnetic resonance in medicine 87 (1), 323-336, 2022 | 6 | 2022 |
Model studies of advanced glycation end product modification of heterograft biomaterials: The effects of in vitro glucose, glyoxal, and serum albumin on collagen structure and … CA Rock, S Keeney, A Zakharchenko, H Takano, DA Spiegel, AM Krieger, ... Acta biomaterialia 123, 275-285, 2021 | 6 | 2021 |
Altered responsiveness to tgfβ and bmp and increased cd45+ cell presence in mitral valves are unique features of ischemic mitral regurgitation E Castillero, DP Howsmon, BV Rego, SJ Keeney, KH Driesbaugh, ... Arteriosclerosis, thrombosis, and vascular biology 41 (6), 2049-2062, 2021 | 3 | 2021 |
Inhibition and down regulation of the serotonin transporter contribute to the progression of degenerative mitral regurgitation RJ Levy, E Fitzpatrick, E Castillero, HJ Shukla, VV Inamdar, AE Aghali, ... bioRxiv, 2020.03. 10.985382, 2020 | 1 | 2020 |
Accumulation of Advanced Glycation End Products Results in Inflammation-Mediated Structural Degeneration of Bioprosthetic Heart Valves A Zakharchenko, S Keeney, SJ Stachelek, G Ferrari, H Takano, R Levy Circulation 140 (Suppl_1), A14543-A14543, 2019 | 1 | 2019 |
Inhibition of Advanced Glycation End Products Formation and Serum Protein Infiltration in Bioprosthetic Heart Valves: Investigations of Anti-Glycation Agents A Zakharchenko, CA Rock, T Thomas, S Keeney, EJ Hall, H Takano, ... Circulation 146 (Suppl_1), A13187-A13187, 2022 | | 2022 |
Polyoxazoline Modification of Bovine Pericardial Bioprosthetic Heart Valve Leaflets Mitigates Protein-Glycation Associated Structural Degeneration A Zakharchenko, S Keeney, IS Alferiev, M Chorny, Y Xue, H Takano, ... Circulation 144 (Suppl_1), A13818-A13818, 2021 | | 2021 |
Deterioration of Glutaraldehyde Crosslinked Heterograft Biomaterials due to Advanced Glycation End Product Formation and Serum Albumin Infiltration CA Rock, S Keeney, A Zakharchenko, H Takano, DA Spiegel, AM Krieger, ... bioRxiv, 2020.05. 28.117739, 2020 | | 2020 |
Serotonin Related Gene Expression Patterns in Aortic Valve Interstitial Cells Are Altered by Proliferation and Serotonin Transporter Inhibition A Aghali, SJ Keeney, EG Fitzpatrick, H Shukla, E Castillero, I Fishbein, ... Circulation 140 (Suppl_1), A15914-A15914, 2019 | | 2019 |
Advanced Glycation End Products Formation Drives Structural Bioprosthetic Valve Degeneration Y Xue, A Frasca, S Keeney, A Zakharchenko, A Kossar, R Levy, G Ferrari Circulation 140 (Suppl_1), A13508-A13508, 2019 | | 2019 |
Advanced Glycation End Products and the Pathophysiology of Bioprosthetic Heart Valve Structural Degeneration A Frasca, S Keeney, S Lee, JE Bavaria, RC Gorman, RJ Levy, G Ferrari Circulation 138 (Suppl_1), A16744-A16744, 2018 | | 2018 |
Magnetic susceptibility, R2* and iron evolve during reperfusion injury wound healing BF Moon, SK Iyer, E Hwuang, NJ Josselyn, JJ Pilla, JH Gorman III, ... | | |