Blood–brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment M Elahy, C Jackaman, JCL Mamo, V Lam, SS Dhaliwal, C Giles, D Nelson, ... Immunity & Ageing 12, 1-9, 2015 | 298 | 2015 |
α-Tocopherol preserves cardiac function by reducing oxidative stress and inflammation in ischemia/reperfusion injury M Wallert, M Ziegler, X Wang, A Maluenda, X Xu, ML Yap, R Witt, C Giles, ... Redox biology 26, 101292, 2019 | 164 | 2019 |
Blood-brain barrier dysfunction precedes cognitive decline and neurodegeneration in diabetic insulin resistant mouse model: an implication for causal link R Takechi, V Lam, E Brook, C Giles, N Fimognari, A Mooranian, ... Frontiers in aging neuroscience 9, 399, 2017 | 136 | 2017 |
Large-scale plasma lipidomic profiling identifies lipids that predict cardiovascular events in secondary prevention PA Mundra, CK Barlow, PJ Nestel, EH Barnes, A Kirby, P Thompson, ... JCI insight 3 (17), 2018 | 113 | 2018 |
High-coverage plasma lipidomics reveals novel sex-specific lipidomic fingerprints of age and BMI: Evidence from two large population cohort studies HB Beyene, G Olshansky, AA T. Smith, C Giles, K Huynh, M Cinel, ... PLoS biology 18 (9), e3000870, 2020 | 112 | 2020 |
Concordant peripheral lipidome signatures in two large clinical studies of Alzheimer’s disease K Huynh, WLF Lim, C Giles, KS Jayawardana, A Salim, NA Mellett, ... Nature communications 11 (1), 5698, 2020 | 94 | 2020 |
Clinical lipidomics: realizing the potential of lipid profiling TG Meikle, K Huynh, C Giles, PJ Meikle Journal of lipid research 62, 2021 | 78 | 2021 |
Nutraceutical agents with anti-inflammatory properties prevent dietary saturated-fat induced disturbances in blood–brain barrier function in wild-type mice R Takechi, MM Pallebage-Gamarallage, V Lam, C Giles, JC Mamo Journal of neuroinflammation 10, 1-12, 2013 | 66 | 2013 |
Lipidomic profiles of the heart and circulation in response to exercise versus cardiac pathology: a resource of potential biomarkers and drug targets YK Tham, BC Bernardo, K Huynh, JYY Ooi, XM Gao, H Kiriazis, C Giles, ... Cell reports 24 (10), 2757-2772, 2018 | 48 | 2018 |
The effect of diesel exhaust exposure on blood–brain barrier integrity and function in a murine model S Heidari Nejad, R Takechi, BJ Mullins, C Giles, AN Larcombe, ... Journal of Applied Toxicology 35 (1), 41-47, 2015 | 47 | 2015 |
Insulin signaling requires glucose to promote lipid anabolism in adipocytes JR Krycer, LE Quek, D Francis, A Zadoorian, FC Weiss, KC Cooke, ... Journal of Biological Chemistry 295 (38), 13250-13266, 2020 | 44 | 2020 |
HDL phospholipids, but not cholesterol distinguish acute coronary syndrome from stable coronary artery disease PJ Meikle, MF Formosa, NA Mellett, KS Jayawardana, C Giles, ... Journal of the American Heart Association 8 (11), e011792, 2019 | 43 | 2019 |
The effects of long-term saturated fat enriched diets on the brain lipidome C Giles, R Takechi, NA Mellett, PJ Meikle, S Dhaliwal, JC Mamo PloS one 11 (12), e0166964, 2016 | 43 | 2016 |
Comprehensive genetic analysis of the human lipidome identifies loci associated with lipid homeostasis with links to coronary artery disease G Cadby, C Giles, PE Melton, K Huynh, NA Mellett, T Duong, A Nguyen, ... Nature communications 13 (1), 3124, 2022 | 41 | 2022 |
Contemporary lipidomic analytics: opportunities and pitfalls C Giles, R Takechi, V Lam, SS Dhaliwal, JCL Mamo Progress in Lipid Research 71, 86-100, 2018 | 38 | 2018 |
Macrophage polarization state affects lipid composition and the channeling of exogenous fatty acids into endogenous lipid pools PK Morgan, K Huynh, G Pernes, PM Miotto, NA Mellett, C Giles, PJ Meikle, ... Journal of Biological Chemistry 297 (6), 2021 | 34 | 2021 |
Heritability of 596 lipid species and genetic correlation with cardiovascular traits in the Busselton Family Heart Study [S] G Cadby, PE Melton, NS McCarthy, C Giles, NA Mellett, K Huynh, J Hung, ... Journal of lipid research 61 (4), 537-545, 2020 | 34 | 2020 |
The serum concentration of the calcium binding protein S100B is positively associated with cognitive performance in older adults V Lam, MA Albrecht, R Takechi, C Giles, AP James, JK Foster, JCL Mamo Frontiers in aging neuroscience 5, 61, 2013 | 33 | 2013 |
Relationships between plasma lipids species, gender, risk factors, and Alzheimer’s disease WLF Lim, K Huynh, P Chatterjee, I Martins, KS Jayawardana, C Giles, ... Journal of Alzheimer's Disease 76 (1), 303-315, 2020 | 30 | 2020 |
Antihypertensive agents do not prevent blood–brain barrier dysfunction and cognitive deficits in dietary-induced obese mice JCL Mamo, V Lam, C Giles, SH Coulson, N Fimognari, A Mooranian, ... International Journal of Obesity 41 (6), 926-934, 2017 | 30 | 2017 |