Transcription factor–mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells FJ Najm, AM Lager, A Zaremba, K Wyatt, AV Caprariello, DC Factor, ... Nature biotechnology 31 (5), 426-433, 2013 | 317 | 2013 |
CNS myelin wrapping is driven by actin disassembly JB Zuchero, M Fu, SA Sloan, A Ibrahim, A Olson, A Zaremba, JC Dugas, ... Developmental cell 34 (2), 152-167, 2015 | 308 | 2015 |
Mechanisms of lysophosphatidylcholine‐induced demyelination: A primary lipid disrupting myelinopathy JR Plemel, NJ Michaels, N Weishaupt, AV Caprariello, MB Keough, ... Glia 66 (2), 327-347, 2018 | 176 | 2018 |
Microglia response following acute demyelination is heterogeneous and limits infiltrating macrophage dispersion JR Plemel, JA Stratton, NJ Michaels, KS Rawji, E Zhang, S Sinha, ... Science advances 6 (3), eaay6324, 2020 | 156 | 2020 |
Bone morphogenetic proteins promote gliosis in demyelinating spinal cord lesions ML Fuller, AK DeChant, B Rothstein, A Caprariello, R Wang, AK Hall, ... Annals of Neurology: Official Journal of the American Neurological …, 2007 | 147 | 2007 |
Axo-myelinic neurotransmission: a novel mode of cell signalling in the central nervous system I Micu, JR Plemel, AV Caprariello, KA Nave, PK Stys Nature Reviews Neuroscience 19 (1), 49-58, 2018 | 138 | 2018 |
Biochemically altered myelin triggers autoimmune demyelination AV Caprariello, JA Rogers, ML Morgan, V Hoghooghi, JR Plemel, ... Proceedings of the National Academy of Sciences 115 (21), 5528-5533, 2018 | 113 | 2018 |
Rapid and robust generation of functional oligodendrocyte progenitor cells from epiblast stem cells FJ Najm, A Zaremba, AV Caprariello, S Nayak, EC Freundt, PC Scacheri, ... Nature methods 8 (11), 957-962, 2011 | 100 | 2011 |
Apoptosis of oligodendrocytes in the central nervous system results in rapid focal demyelination AV Caprariello, S Mangla, RH Miller, SM Selkirk Annals of neurology 72 (3), 395-405, 2012 | 94 | 2012 |
Oligodendrocyte death and myelin loss in the cuprizone model: an updated overview of the intrinsic and extrinsic causes of cuprizone demyelination M Zirngibl, P Assinck, A Sizov, AV Caprariello, JR Plemel Molecular neurodegeneration 17 (1), 34, 2022 | 89 | 2022 |
In vivo quantification of myelin changes in the vertebrate nervous system Y Wang, C Wu, AV Caprariello, E Somoza, W Zhu, C Wang, RH Miller Journal of Neuroscience 29 (46), 14663-14669, 2009 | 85 | 2009 |
The PPARγ agonist pioglitazone crosses the blood–brain barrier and reduces tumor growth in a human xenograft model C Grommes, JC Karlo, A Caprariello, DA Blankenship, A DeChant, ... Cancer chemotherapy and pharmacology 71, 929-936, 2013 | 80 | 2013 |
Unique spectral signatures of the nucleic acid dye acridine orange can distinguish cell death by apoptosis and necroptosis JR Plemel, AV Caprariello, MB Keough, TJ Henry, S Tsutsui, TH Chu, ... Journal of Cell Biology 216 (4), 1163-1181, 2017 | 70 | 2017 |
Nile Red fluorescence spectroscopy reports early physicochemical changes in myelin with high sensitivity W Teo, AV Caprariello, ML Morgan, A Luchicchi, GJ Schenk, JT Joseph, ... Proceedings of the National Academy of Sciences 118 (8), e2016897118, 2021 | 53 | 2021 |
Apoptosis of oligodendrocytes during early development delays myelination and impairs subsequent responses to demyelination AV Caprariello, CE Batt, I Zippe, RR Romito-DiGiacomo, M Karl, RH Miller Journal of Neuroscience 35 (41), 14031-14041, 2015 | 39 | 2015 |
Development of a PET radioligand for potassium channels to image CNS demyelination P Brugarolas, JE Sánchez-Rodríguez, HM Tsai, F Basuli, SH Cheng, ... Scientific reports 8 (1), 607, 2018 | 34 | 2018 |
Inhibitors of protein arginine deiminases and their efficacy in animal models of multiple sclerosis A Sarswat, E Wasilewski, SK Chakka, AM Bello, AV Caprariello, ... Bioorganic & medicinal chemistry 25 (9), 2643-2656, 2017 | 22 | 2017 |
Foamy virus as a gene transfer vector to the central nervous system AV Caprariello, RH Miller, SM Selkirk Gene therapy 16 (3), 448-452, 2009 | 15 | 2009 |
Animal Models for the Study of Human Disease: Chapter 42. Animal Models for the Study of Multiple Sclerosis RH Miller, SL Fyffe-Maricich, AV Caprariello Elsevier, 2013 | 13* | 2013 |
Single-cell microglial transcriptomics during demyelination defines a microglial state required for lytic carcass clearance S Zia, BP Hammond, M Zirngibl, A Sizov, CS Baaklini, SP Panda, MFS Ho, ... Molecular Neurodegeneration 17 (1), 82, 2022 | 12 | 2022 |