HTR7 mediates serotonergic acute and chronic itch T Morita, SP McClain, LM Batia, M Pellegrino, SR Wilson, MA Kienzler, ... Neuron 87 (1), 124-138, 2015 | 201 | 2015 |
Chronic granulomatous disease: a large, single-center US experience P Bortoletto, K Lyman, A Camacho, M Fricchione, A Khanolkar, BZ Katz The Pediatric infectious disease journal 34 (10), 1110-1114, 2015 | 89 | 2015 |
HCN-channel dendritic targeting requires bipartite interaction with TRIP8b and regulates antidepressant-like behavioral effects Y Han, RJ Heuermann, KA Lyman, D Fisher, QA Ismail, DM Chetkovich Molecular psychiatry 22 (3), 458-465, 2017 | 50 | 2017 |
Reduction of thalamic and cortical Ih by deletion of TRIP8b produces a mouse model of human absence epilepsy RJ Heuermann, TC Jaramillo, SW Ying, BA Suter, KA Lyman, Y Han, ... Neurobiology of disease 85, 81-92, 2016 | 45 | 2016 |
Neuroinflammation alters integrative properties of rat hippocampal pyramidal cells F Frigerio, C Flynn, Y Han, K Lyman, JN Lugo, T Ravizza, A Ghestem, ... Molecular neurobiology 55, 7500-7511, 2018 | 44 | 2018 |
The structure and function of TRIP8b, an auxiliary subunit of hyperpolarization-activated cyclic-nucleotide gated channels Y Han, KA Lyman, KM Foote, DM Chetkovich Channels 14 (1), 110-122, 2020 | 30 | 2020 |
Current opinions and consensus for studying tremor in animal models SH Kuo, ED Louis, PL Faust, A Handforth, S Chang, B Avlar, EJ Lang, ... The Cerebellum 18, 1036-1063, 2019 | 30 | 2019 |
Phosphorylation of the HCN channel auxiliary subunit TRIP8b is altered in an animal model of temporal lobe epilepsy and modulates channel function KM Foote, KA Lyman, Y Han, IE Michailidis, RJ Heuermann, D Mandikian, ... Journal of Biological Chemistry 294 (43), 15743-15758, 2019 | 25 | 2019 |
Identification of small-molecule inhibitors of hyperpolarization-activated cyclic nucleotide–gated channels Y Han, K Lyman, M Clutter, GE Schiltz, QA Ismail, DB Prados, CH Luan, ... Journal of biomolecular screening 20 (9), 1124-1131, 2015 | 25 | 2015 |
Animal models suggest the TRIP8b-HCN interaction is a therapeutic target for major depressive disorder KA Lyman, Y Han, DM Chetkovich Expert Opinion on Therapeutic Targets 21 (3), 235-237, 2017 | 24 | 2017 |
Reconciling the influence of task-set switching and motor inhibition processes on stop signal after-effects JA Anguera, K Lyman, TP Zanto, J Bollinger, A Gazzaley Frontiers in Psychology 4, 649, 2013 | 22 | 2013 |
HCN channels in the hippocampus regulate active coping behavior DW Fisher, Y Han, KA Lyman, RJ Heuermann, LA Bean, N Ybarra, ... Journal of neurochemistry 146 (6), 753-766, 2018 | 17 | 2018 |
A novel method for reducing human pipetting errors K Lyman, D Fisher, Y Han, DM Chetkovich Journal of Medical Laboratory and Diagnosis 6 (6), 36-40, 2015 | 16 | 2015 |
Allostery between two binding sites in the ion channel subunit TRIP8b confers binding specificity to HCN channels KA Lyman, Y Han, RJ Heuermann, X Cheng, JE Kurz, RE Lyman, ... Journal of Biological Chemistry 292 (43), 17718-17730, 2017 | 15 | 2017 |
Hippocampal cAMP regulates HCN channel function on two time scales with differential effects on animal behavior KA Lyman, Y Han, C Zhou, I Renteria, GL Besing, JE Kurz, ... Science translational medicine 13 (621), eabl4580, 2021 | 9 | 2021 |
Method for identifying small molecule inhibitors of the protein-protein interaction between HCN1 and TRIP8b Y Han, KA Lyman, M Clutter, GE Schiltz, QA Ismail, X Cheng, CH Luan, ... JoVE (Journal of Visualized Experiments), e54540, 2016 | 7 | 2016 |
Cortical Compass: EML1 Helps Point the Way in Neuronal Migration: EML1 Mutations Cause Cortical Heterotopia KA Lyman, DM Chetkovich Epilepsy Currents 15 (1), 43-44, 2015 | 6 | 2015 |
Discovery of a small-molecule inhibitor of the TRIP8b–HCN interaction with efficacy in neurons Y Han, ID Iyamu, MR Clutter, RK Mishra, KA Lyman, C Zhou, I Michailidis, ... Journal of Biological Chemistry 298 (7), 2022 | 4 | 2022 |
New insights into postictal paresis: an epilepsy-associated phenomenon that may not be as benign as long thought KA Lyman, D Chetkovich Epilepsy Currents 17 (3), 167-168, 2017 | 3 | 2017 |
CRAFTing a new approach to antiepileptic drug discovery KA Lyman, DM Chetkovich Epilepsy Currents 19 (3), 182-183, 2019 | 2 | 2019 |