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Kyle A. Lyman
Kyle A. Lyman
在 mgh.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
HTR7 mediates serotonergic acute and chronic itch
T Morita, SP McClain, LM Batia, M Pellegrino, SR Wilson, MA Kienzler, ...
Neuron 87 (1), 124-138, 2015
2012015
Chronic granulomatous disease: a large, single-center US experience
P Bortoletto, K Lyman, A Camacho, M Fricchione, A Khanolkar, BZ Katz
The Pediatric infectious disease journal 34 (10), 1110-1114, 2015
892015
HCN-channel dendritic targeting requires bipartite interaction with TRIP8b and regulates antidepressant-like behavioral effects
Y Han, RJ Heuermann, KA Lyman, D Fisher, QA Ismail, DM Chetkovich
Molecular psychiatry 22 (3), 458-465, 2017
502017
Reduction of thalamic and cortical Ih by deletion of TRIP8b produces a mouse model of human absence epilepsy
RJ Heuermann, TC Jaramillo, SW Ying, BA Suter, KA Lyman, Y Han, ...
Neurobiology of disease 85, 81-92, 2016
452016
Neuroinflammation alters integrative properties of rat hippocampal pyramidal cells
F Frigerio, C Flynn, Y Han, K Lyman, JN Lugo, T Ravizza, A Ghestem, ...
Molecular neurobiology 55, 7500-7511, 2018
442018
The structure and function of TRIP8b, an auxiliary subunit of hyperpolarization-activated cyclic-nucleotide gated channels
Y Han, KA Lyman, KM Foote, DM Chetkovich
Channels 14 (1), 110-122, 2020
302020
Current opinions and consensus for studying tremor in animal models
SH Kuo, ED Louis, PL Faust, A Handforth, S Chang, B Avlar, EJ Lang, ...
The Cerebellum 18, 1036-1063, 2019
302019
Phosphorylation of the HCN channel auxiliary subunit TRIP8b is altered in an animal model of temporal lobe epilepsy and modulates channel function
KM Foote, KA Lyman, Y Han, IE Michailidis, RJ Heuermann, D Mandikian, ...
Journal of Biological Chemistry 294 (43), 15743-15758, 2019
252019
Identification of small-molecule inhibitors of hyperpolarization-activated cyclic nucleotide–gated channels
Y Han, K Lyman, M Clutter, GE Schiltz, QA Ismail, DB Prados, CH Luan, ...
Journal of biomolecular screening 20 (9), 1124-1131, 2015
252015
Animal models suggest the TRIP8b-HCN interaction is a therapeutic target for major depressive disorder
KA Lyman, Y Han, DM Chetkovich
Expert Opinion on Therapeutic Targets 21 (3), 235-237, 2017
242017
Reconciling the influence of task-set switching and motor inhibition processes on stop signal after-effects
JA Anguera, K Lyman, TP Zanto, J Bollinger, A Gazzaley
Frontiers in Psychology 4, 649, 2013
222013
HCN channels in the hippocampus regulate active coping behavior
DW Fisher, Y Han, KA Lyman, RJ Heuermann, LA Bean, N Ybarra, ...
Journal of neurochemistry 146 (6), 753-766, 2018
172018
A novel method for reducing human pipetting errors
K Lyman, D Fisher, Y Han, DM Chetkovich
Journal of Medical Laboratory and Diagnosis 6 (6), 36-40, 2015
162015
Allostery between two binding sites in the ion channel subunit TRIP8b confers binding specificity to HCN channels
KA Lyman, Y Han, RJ Heuermann, X Cheng, JE Kurz, RE Lyman, ...
Journal of Biological Chemistry 292 (43), 17718-17730, 2017
152017
Hippocampal cAMP regulates HCN channel function on two time scales with differential effects on animal behavior
KA Lyman, Y Han, C Zhou, I Renteria, GL Besing, JE Kurz, ...
Science translational medicine 13 (621), eabl4580, 2021
92021
Method for identifying small molecule inhibitors of the protein-protein interaction between HCN1 and TRIP8b
Y Han, KA Lyman, M Clutter, GE Schiltz, QA Ismail, X Cheng, CH Luan, ...
JoVE (Journal of Visualized Experiments), e54540, 2016
72016
Cortical Compass: EML1 Helps Point the Way in Neuronal Migration: EML1 Mutations Cause Cortical Heterotopia
KA Lyman, DM Chetkovich
Epilepsy Currents 15 (1), 43-44, 2015
62015
Discovery of a small-molecule inhibitor of the TRIP8b–HCN interaction with efficacy in neurons
Y Han, ID Iyamu, MR Clutter, RK Mishra, KA Lyman, C Zhou, I Michailidis, ...
Journal of Biological Chemistry 298 (7), 2022
42022
New insights into postictal paresis: an epilepsy-associated phenomenon that may not be as benign as long thought
KA Lyman, D Chetkovich
Epilepsy Currents 17 (3), 167-168, 2017
32017
CRAFTing a new approach to antiepileptic drug discovery
KA Lyman, DM Chetkovich
Epilepsy Currents 19 (3), 182-183, 2019
22019
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