Hetero-oligomerization of CCR2, CCR5, and CXCR4 and the protean effects of “selective” antagonists D Sohy, H Yano, P De Nadai, E Urizar, A Guillabert, JA Javitch, ... Journal of Biological Chemistry 284 (45), 31270-31279, 2009 | 194 | 2009 |
A mechanism for intracellular release of Na+ by neurotransmitter/sodium symporters L Malinauskaite, M Quick, L Reinhard, JA Lyons, H Yano, JA Javitch, ... Nature structural & molecular biology 21 (11), 1006-1012, 2014 | 185 | 2014 |
Evidence against dopamine D1/D2 receptor heteromers AL Frederick, H Yano, P Trifilieff, HD Vishwasrao, D Biezonski, ... Molecular psychiatry 20 (11), 1373-1385, 2015 | 144 | 2015 |
Functional selectivity of allosteric interactions within G protein–coupled receptor oligomers: the dopamine D1-D3 receptor heterotetramer X Guitart, G Navarro, E Moreno, H Yano, NS Cai, M Sánchez-Soto, ... Molecular pharmacology 86 (4), 417-429, 2014 | 140 | 2014 |
CODA-RET reveals functional selectivity as a result of GPCR heteromerization E Urizar, H Yano, R Kolster, C Galés, N Lambert, JA Javitch Nature chemical biology 7 (9), 624-630, 2011 | 127 | 2011 |
State-dependent conformations of the translocation pathway in the tyrosine transporter Tyt1, a novel neurotransmitter: sodium symporter from Fusobacterium nucleatum M Quick, H Yano, NR Goldberg, L Duan, T Beuming, L Shi, H Weinstein, ... Journal of Biological Chemistry 281 (36), 26444-26454, 2006 | 105 | 2006 |
The sigma-1 receptor modulates dopamine transporter conformation and cocaine binding and may thereby potentiate cocaine self-administration in rats WC Hong, H Yano, T Hiranita, FT Chin, CR McCurdy, TP Su, SG Amara, ... Journal of Biological Chemistry 292 (27), 11250-11261, 2017 | 89 | 2017 |
Dopamine receptor activation increases HIV entry into primary human macrophages PJ Gaskill, HH Yano, GV Kalpana, JA Javitch, JW Berman PloS one 9 (9), e108232, 2014 | 86 | 2014 |
The membrane raft protein Flotillin-1 is essential in dopamine neurons for amphetamine-induced behavior in Drosophila AB Pizzo, CS Karam, Y Zhang, H Yano, RJ Freyberg, DS Karam, ... Molecular psychiatry 18 (7), 824-833, 2013 | 84 | 2013 |
Evidence for noncanonical neurotransmitter activation: norepinephrine as a dopamine D2-like receptor agonist M Sánchez-Soto, A Bonifazi, NS Cai, MP Ellenberger, AH Newman, ... Molecular pharmacology 89 (4), 457-466, 2016 | 80 | 2016 |
Anesthetic inhibition in ischemic and nonischemic murine heart: comparison with conscious echocardiographic approach S Takuma, K Suehiro, C Cardinale, T Hozumi, H Yano, J Shimizu, ... American Journal of Physiology-Heart and Circulatory Physiology 280 (5 …, 2001 | 80 | 2001 |
HIV, Tat and dopamine transmission PJ Gaskill, DR Miller, J Gamble-George, H Yano, H Khoshbouei Neurobiology of disease 105, 51-73, 2017 | 69 | 2017 |
Control of glutamate release by complexes of adenosine and cannabinoid receptors A Köfalvi, E Moreno, A Cordomí, NS Cai, V Fernández-Dueñas, ... BMC biology 18, 1-21, 2020 | 68 | 2020 |
Novel and high affinity 2-[(diphenylmethyl) sulfinyl] acetamide (modafinil) analogues as atypical dopamine transporter inhibitors J Cao, RD Slack, OM Bakare, C Burzynski, R Rais, BS Slusher, T Kopajtic, ... Journal of medicinal chemistry 59 (23), 10676-10691, 2016 | 68 | 2016 |
Pharmacological profiling of sigma 1 receptor ligands by novel receptor homomer assays H Yano, A Bonifazi, M Xu, DA Guthrie, SN Schneck, AM Abramyan, ... Neuropharmacology 133, 264-275, 2018 | 64 | 2018 |
High-frequency activation of nucleus accumbens D1-MSNs drives excitatory potentiation on D2-MSNs TC Francis, H Yano, TG Demarest, H Shen, A Bonci Neuron 103 (3), 432-444. e3, 2019 | 60 | 2019 |
Toward Understanding the Structural Basis of Partial Agonism at the Dopamine D3 Receptor M Michino, CA Boateng, P Donthamsetti, H Yano, OM Bakare, A Bonifazi, ... Journal of medicinal chemistry 60 (2), 580-593, 2017 | 55 | 2017 |
Novel and Potent Dopamine D2 Receptor Go-Protein Biased Agonists A Bonifazi, H Yano, AM Guerrero, V Kumar, AF Hoffman, CR Lupica, L Shi, ... ACS pharmacology & translational science 2 (1), 52-65, 2019 | 50 | 2019 |
Gs- versus Golf-dependent functional selectivity mediated by the dopamine D1 receptor H Yano, NS Cai, M Xu, RK Verma, W Rea, AF Hoffman, L Shi, JA Javitch, ... Nature communications 9 (1), 486, 2018 | 48 | 2018 |
Novel Bivalent Ligands Based on the Sumanirole Pharmacophore Reveal Dopamine D2 Receptor (D2R) Biased Agonism A Bonifazi, H Yano, MP Ellenberger, L Muller, V Kumar, MF Zou, NS Cai, ... Journal of medicinal chemistry 60 (7), 2890-2907, 2017 | 43 | 2017 |