Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation J Ehrhart, D Obregon, T Mori, H Hou, N Sun, Y Bai, T Klein, F Fernandez, ... Journal of neuroinflammation 2, 1-13, 2005 | 447 | 2005 |
Inflammaging as a prodrome to Alzheimer's disease B Giunta, F Fernandez, WV Nikolic, D Obregon, E Rrapo, T Town, J Tan Journal of neuroinflammation 5, 1-15, 2008 | 388 | 2008 |
ADAM10 activation is required for green tea (–)-epigallocatechin-3-gallate-induced α-secretase cleavage of amyloid precursor protein DF Obregon, K Rezai-Zadeh, Y Bai, N Sun, H Hou, J Ehrhart, J Zeng, ... Journal of Biological Chemistry 281 (24), 16419-16427, 2006 | 248 | 2006 |
Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice J Tan, T Town, F Crawford, T Mori, A DelleDonne, R Crescentini, ... Nature neuroscience 5 (12), 1288-1293, 2002 | 243 | 2002 |
Soluble amyloid precursor protein-α modulates β-secretase activity and amyloid-β generation D Obregon, H Hou, J Deng, B Giunta, J Tian, D Darlington, ... Nature communications 3 (1), 777, 2012 | 221 | 2012 |
Inhibition of angiogenesis by Aβ peptides D Paris, K Townsend, A Quadros, J Humphrey, J Sun, S Brem, ... Angiogenesis 7, 75-85, 2004 | 175 | 2004 |
Flavonoid‐mediated presenilin‐1 phosphorylation reduces Alzheimer's disease β‐amyloid production K Rezai‐Zadeh, R Douglas Shytle, Y Bai, J Tian, H Hou, T Mori, J Zeng, ... Journal of cellular and molecular medicine 13 (3), 574-588, 2009 | 162 | 2009 |
The immunology of traumatic brain injury: a prime target for Alzheimer’s disease prevention B Giunta, D Obregon, R Velisetty, PR Sanberg, CV Borlongan, J Tan Journal of neuroinflammation 9, 1-8, 2012 | 148 | 2012 |
CD40 is expressed and functional on neuronal cells J Tan, T Town, T Mori, D Obregon, Y Wu, A DelleDonne, A Rojiani, ... The EMBO journal, 2002 | 147 | 2002 |
Luteolin reduces Alzheimer’s disease pathologies induced by traumatic brain injury D Sawmiller, S Li, M Shahaduzzaman, AJ Smith, D Obregon, B Giunta, ... International journal of molecular sciences 15 (1), 895-904, 2014 | 140 | 2014 |
Antiretroviral medications disrupt microglial phagocytosis of β-amyloid and increase its production by neurons: implications for HIV-associated neurocognitive disorders B Giunta, J Ehrhart, DF Obregon, L Lam, L Le, JJ Jin, F Fernandez, J Tan, ... Molecular brain 4, 1-6, 2011 | 129 | 2011 |
p35/Cdk5 pathway mediates soluble amyloid‐β peptide‐induced tau phosphorylation in vitro T Town, J Zolton, R Shaffner, B Schnell, R Crescentini, Y Wu, J Zeng, ... Journal of neuroscience research 69 (3), 362-372, 2002 | 127 | 2002 |
Baicalein reduces β‐amyloid and promotes nonamyloidogenic amyloid precursor protein processing in an Alzheimer's disease transgenic mouse model SQ Zhang, D Obregon, J Ehrhart, J Deng, J Tian, H Hou, B Giunta, ... Journal of neuroscience research 91 (9), 1239-1246, 2013 | 119 | 2013 |
Proinflammatory and vasoactive effects of Aβ in the cerebrovasculature KP Townsend, D Obregon, A Quadros, N Patel, CH Volmar, D Paris, ... Annals of the New York Academy of Sciences 977 (1), 65-76, 2002 | 117 | 2002 |
EGCG functions through estrogen receptor-mediated activation of ADAM10 in the promotion of non-amyloidogenic processing of APP JW Fernandez, K Rezai-Zadeh, D Obregon, J Tan FEBS letters 584 (19), 4259-4267, 2010 | 105 | 2010 |
CD45 deficiency drives amyloid-β peptide oligomers and neuronal loss in Alzheimer's disease mice Y Zhu, H Hou, K Rezai-Zadeh, B Giunta, A Ruscin, C Gemma, JJ Jin, ... Journal of Neuroscience 31 (4), 1355-1365, 2011 | 101 | 2011 |
Characterization of murine immunoglobulin G antibodies against human amyloid-β1–42 T Town, J Tan, N Sansone, D Obregon, T Klein, M Mullan Neuroscience Letters 307 (2), 101-104, 2001 | 99 | 2001 |
Peripheral biomarkers in autism: secreted amyloid precursor protein-α as a probable key player in early diagnosis AR Bailey, BN Giunta, D Obregon, WV Nikolic, J Tian, CD Sanberg, ... International journal of clinical and experimental medicine 1 (4), 338, 2008 | 98 | 2008 |
Soluble amyloid precursor protein alpha inhibits tau phosphorylation through modulation of GSK 3β signaling pathway J Deng, A Habib, DF Obregon, SW Barger, B Giunta, YJ Wang, H Hou, ... Journal of neurochemistry 135 (3), 630-637, 2015 | 92 | 2015 |
Transcutaneous β-amyloid immunization reduces cerebral β-amyloid deposits without T cell infiltration and microhemorrhage WV Nikolic, Y Bai, D Obregon, H Hou, T Mori, J Zeng, J Ehrhart, RD Shytle, ... Proceedings of the National Academy of Sciences 104 (7), 2507-2512, 2007 | 90 | 2007 |