| Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation C Charrier, K Joshi, J Coutinho-Budd, JE Kim, N Lambert, J De Marchena, ... Cell 149 (4), 923-935, 2012 | 466 | 2012 |
| The F-BAR domain of srGAP2 induces membrane protrusions required for neuronal migration and morphogenesis S Guerrier, J Coutinho-Budd, T Sassa, A Gresset, NV Jordan, K Chen, ... Cell 138 (5), 990-1004, 2009 | 399 | 2009 |
| The habenula is crucial for experience-dependent modification of fear responses in zebrafish M Agetsuma, H Aizawa, T Aoki, R Nakayama, M Takahoko, M Goto, ... Nature neuroscience 13 (11), 1354-1356, 2010 | 395 | 2010 |
| ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis Y Ohno, S Suto, M Yamanaka, Y Mizutani, S Mitsutake, Y Igarashi, ... Proceedings of the National Academy of Sciences 107 (43), 18439-18444, 2010 | 388 | 2010 |
| Metabolism of very long-chain fatty acids: genes and pathophysiology T Sassa, A Kihara Biomolecules & therapeutics 22 (2), 83, 2014 | 280 | 2014 |
| Impaired epidermal permeability barrier in mice lacking elovl1, the gene responsible for very-long-chain fatty acid production T Sassa, Y Ohno, S Suzuki, T Nomura, C Nishioka, T Kashiwagi, ... Molecular and cellular biology 33 (14), 2787-2796, 2013 | 176 | 2013 |
| In vivo conversion of cellular prion protein to pathogenic isoforms, as monitored by conformation-specific antibodies T Yokoyama, KM Kimura, Y Ushiki, S Yamada, A Morooka, T Nakashiba, ... Journal of Biological Chemistry 276 (14), 11265-11271, 2001 | 125 | 2001 |
| Biochemical characterization of the very long‐chain fatty acid elongase ELOVL7 T Naganuma, Y Sato, T Sassa, Y Ohno, A Kihara FEBS letters 585 (20), 3337-3341, 2011 | 120 | 2011 |
| A shift in sphingolipid composition from C24 to C16 increases susceptibility to apoptosis in HeLa cells T Sassa, S Suto, Y Okayasu, A Kihara Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2012 | 111 | 2012 |
| Enzyme activities of the ceramide synthases CERS2–6 are regulated by phosphorylation in the C-terminal region T Sassa, T Hirayama, A Kihara Journal of Biological Chemistry 291 (14), 7477-7487, 2016 | 91 | 2016 |
| Topography of thalamic projections requires attractive and repulsive functions of Netrin-1 in the ventral telencephalon AW Powell, T Sassa, Y Wu, M Tessier-Lavigne, F Polleux PLoS biology 6 (5), e116, 2008 | 76 | 2008 |
| De novo mutation in ELOVL1 causes ichthyosis, acanthosis nigricans, hypomyelination, spastic paraplegia, high frequency deafness and optic atrophy N Mueller, T Sassa, S Morales-Gonzalez, J Schneider, DJ Salchow, ... Journal of medical genetics 56 (3), 164-175, 2019 | 71 | 2019 |
| Lorenzo's oil inhibits ELOVL1 and lowers the level of sphingomyelin with a saturated very long-chain fatty acids T Sassa, T Wakashima, Y Ohno, A Kihara Journal of lipid research 55 (3), 524-530, 2014 | 62 | 2014 |
| Very long-chain tear film lipids produced by fatty acid elongase ELOVL1 prevent dry eye disease in mice T Sassa, M Tadaki, H Kiyonari, A Kihara The FASEB Journal 32 (6), 2966-2978, 2018 | 61 | 2018 |
| Cooperative synthesis of ultra long-chain fatty acid and ceramide during keratinocyte differentiation Y Mizutani, H Sun, Y Ohno, T Sassa, T Wakashima, M Obara, K Yuyama, ... PloS one 8 (6), e67317, 2013 | 55 | 2013 |
| The 3-hydroxyacyl-CoA dehydratases HACD1 and HACD2 exhibit functional redundancy and are active in a wide range of fatty acid elongation pathways M Sawai, Y Uchida, Y Ohno, M Miyamoto, C Nishioka, S Itohara, T Sassa, ... Journal of Biological Chemistry 292 (37), 15538-15551, 2017 | 48 | 2017 |
| Lipid polarity gradient formed by ω-hydroxy lipids in tear film prevents dry eye disease M Miyamoto, T Sassa, M Sawai, A Kihara Elife 9, e53582, 2020 | 44 | 2020 |
| Disruption of the Sjögren-Larsson syndrome gene Aldh3a2 in mice increases keratinocyte growth and retards skin barrier recovery T Naganuma, S Takagi, T Kanetake, T Kitamura, S Hattori, T Miyakawa, ... Journal of Biological Chemistry 291 (22), 11676-11688, 2016 | 37 | 2016 |
| Mutation for nonsyndromic mental retardation in the trans-2-enoyl-CoA reductase TER gene involved in fatty acid elongation impairs the enzyme activity and stability, leading to … K Abe, Y Ohno, T Sassa, R Taguchi, M Çalışkan, C Ober, A Kihara Journal of biological chemistry 288 (51), 36741-36749, 2013 | 36 | 2013 |
| Severe skin permeability barrier dysfunction in knockout mice deficient in a fatty acid ω-hydroxylase crucial to acylceramide production M Miyamoto, N Itoh, M Sawai, T Sassa, A Kihara Journal of Investigative Dermatology 140 (2), 319-326. e4, 2020 | 35 | 2020 |
