Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer MJ Watt, AK Clark, LA Selth, VR Haynes, N Lister, R Rebello, LH Porter, ... Science translational medicine 11 (478), eaau5758, 2019 | 284 | 2019 |
Identification of metabolically distinct adipocyte progenitor cells in human adipose tissues A Raajendiran, G Ooi, J Bayliss, PE O’Brien, RB Schittenhelm, AK Clark, ... Cell reports 27 (5), 1528-1540. e7, 2019 | 130 | 2019 |
Patient-derived models of abiraterone-and enzalutamide-resistant prostate cancer reveal sensitivity to ribosome-directed therapy MG Lawrence, D Obinata, S Sandhu, LA Selth, SQ Wong, LH Porter, ... European urology 74 (5), 562-572, 2018 | 104 | 2018 |
The dual inhibition of RNA Pol I transcription and PIM kinase as a new therapeutic approach to treat advanced prostate cancer RJ Rebello, E Kusnadi, DP Cameron, HB Pearson, A Lesmana, JR Devlin, ... Clinical Cancer Research 22 (22), 5539-5552, 2016 | 83 | 2016 |
A bioengineered microenvironment to quantitatively measure the tumorigenic properties of cancer-associated fibroblasts in human prostate cancer AK Clark, AV Taubenberger, RA Taylor, B Niranjan, ZY Chea, E Zotenko, ... Biomaterials 34 (20), 4777-4785, 2013 | 77 | 2013 |
The MURAL collection of prostate cancer patient-derived xenografts enables discovery through preclinical models of uro-oncology GP Risbridger, AK Clark, LH Porter, R Toivanen, A Bakshi, NL Lister, ... Nature communications 12 (1), 5049, 2021 | 48 | 2021 |
A rare castration‐resistant progenitor cell population is highly enriched in Pten‐null prostate tumours L Sackmann Sala, F Boutillon, G Menara, A De Goyon‐Pélard, ... The Journal of pathology 243 (1), 51-64, 2017 | 38 | 2017 |
Obesity does not promote tumorigenesis of localized patient-derived prostate cancer xenografts JCY Lo, AK Clark, N Ascui, M Frydenberg, GP Risbridger, RA Taylor, ... Oncotarget 7 (30), 47650, 2016 | 23 | 2016 |
Establishing a cryopreservation protocol for patient‐derived xenografts of prostate cancer LH Porter, MG Lawrence, H Wang, AK Clark, A Bakshi, D Obinata, ... The Prostate 79 (11), 1326-1337, 2019 | 21 | 2019 |
Androgen receptor enhancer amplification in matched patient‐derived xenografts of primary and castrate‐resistant prostate cancer LH Porter, A Bakshi, D Pook, A Clark, D Clouston, J Kourambas, ... The Journal of pathology 254 (2), 121-134, 2021 | 17 | 2021 |
Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer. Sci Transl Med. 2019; 11 MJ Watt, AK Clark, LA Selth, VR Haynes, N Lister, R Rebello | 8 | |
Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer. Sci Transl Med 11: eaau5758 MJ Watt, AK Clark, LA Selth, VR Haynes, N Lister, R Rebello, LH Porter, ... | 7 | 2019 |
Potent stimulation of the androgen receptor instigates a viral mimicry response in prostate cancer M Alizadeh-Ghodsi, KL Owen, SL Townley, D Zanker, SPG Rollin, ... Cancer research communications 2 (7), 706-724, 2022 | 6 | 2022 |
Early intervention exercise training does not delay prostate cancer progression in Pten−/− mice RA Taylor, SG Farrelly, AK Clark, MJ Watt The Prostate 80 (11), 906-914, 2020 | 6 | 2020 |
The future of patient-derived xenografts in prostate cancer research MG Lawrence, RA Taylor, GB Cuffe, LS Ang, AK Clark, DL Goode, ... Nature Reviews Urology 20 (6), 371-384, 2023 | 4 | 2023 |
Mast cell interactions at tumour interface drive progression in human prostate cancer G Risbridger, S Ellem, R Taylor, M Frydenberg, D Pook, J Pedersen, ... Endocrine Abstracts 35, 2014 | 1 | 2014 |
Defining the challenges and opportunities for using patient‐derived models in prostate cancer research WN Brennen, C Le Magnen, S Karkampouna, N Anselmino, N Bock, ... The Prostate 84 (7), 623-635, 2024 | | 2024 |
Defining focal neuroendocrine differentiation as a transcriptionally distinct form of prostate cancer pathology characterized by the expression of androgen receptors S Keerthikumar, A Clark, H Wang, B Phipson, A Bakshi, A Ryan, ... | | 2024 |
Defining focal neuroendocrine differentiation as a transcriptionally distinct form of prostate cancer pathology characterized by the expression of androgen receptors R Quezada Urban, S Keerthikumar, A Clark, H Wang, B Phipson, ... bioRxiv, 2024.03. 17.585125, 2024 | | 2024 |
Abstract PR006: PMR-116, a novel inhibitor of ribosome biogenesis with antitumor activity in preclinical models of prostate cancer A Huglo, S Hedwards, M Lawrence, R Rebello, A Clark, G Risbridger, ... Cancer Research 83 (11_Supplement), PR006-PR006, 2023 | | 2023 |