| Challenges and perspectives on the development of small-molecule EGFR inhibitors against T790M-mediated resistance in non-small-cell lung cancer: miniperspective Z Song, Y Ge, C Wang, S Huang, X Shu, K Liu, Y Zhou, X Ma Journal of medicinal chemistry 59 (14), 6580-6594, 2016 | 97 | 2016 |
| Tyrosine phosphatase SHP2 inhibitors in tumor-targeted therapies Z Song, M Wang, Y Ge, XP Chen, Z Xu, Y Sun, XF Xiong Acta Pharmaceutica Sinica B 11 (1), 13-29, 2021 | 84 | 2021 |
| Synthesis and biological evaluation of morpholine-substituted diphenylpyrimidine derivatives (Mor-DPPYs) as potent EGFR T790M inhibitors with improved activity toward the … Z Song, S Huang, H Yu, Y Jiang, C Wang, Q Meng, X Shu, H Sun, K Liu, ... European Journal of Medicinal Chemistry 133, 329-339, 2017 | 49 | 2017 |
| Adenine: an important drug scaffold for the design of antiviral agents C Wang, Z Song, H Yu, K Liu, X Ma Acta pharmaceutica sinica B 5 (5), 431-441, 2015 | 36 | 2015 |
| Novel 4-anilinoquinazoline derivatives featuring an 1-adamantyl moiety as potent EGFR inhibitors with enhanced activity against NSCLC cell lines H Yu, Y Li, Y Ge, Z Song, C Wang, S Huang, Y Jin, X Han, Y Zhen, K Liu, ... European Journal of Medicinal Chemistry 110, 195-203, 2016 | 31 | 2016 |
| Synthesis and biological evaluation of azole-diphenylpyrimidine derivatives (AzDPPYs) as potent T790M mutant form of epidermal growth factor receptor inhibitors Z Song, Y Jin, Y Ge, C Wang, J Zhang, Z Tang, J Peng, K Liu, Y Li, X Ma Bioorganic & Medicinal Chemistry 24 (21), 5505-5512, 2016 | 30 | 2016 |
| Targeting mutated GTPase KRAS in tumor therapies G Fan, L Lou, Z Song, X Zhang, XF Xiong European Journal of Medicinal Chemistry 226, 113816, 2021 | 28 | 2021 |
| Cleavable and tunable cysteine-specific arylation modification with aryl thioethers J Li, JJ Deng, Z Yin, QL Hu, Y Ge, Z Song, Y Zhang, ASC Chan, H Li, ... Chemical Science 12 (14), 5209-5215, 2021 | 27 | 2021 |
| Silanol: a bifunctional group for peptide synthesis and late-stage functionalization QL Hu, KQ Hou, J Li, Y Ge, ZD Song, ASC Chan, XF Xiong Chemical Science 11 (23), 6070-6074, 2020 | 27 | 2020 |
| One-pot conversion of lysine to caprolactam over Ir/H-Beta catalysts J Sebastian, M Zheng, Y Jiang, Y Zhao, H Wang, Z Song, X Li, J Pang, ... Green Chemistry 21 (9), 2462-2468, 2019 | 27 | 2019 |
| Discovery and structural optimization of toddacoumalone derivatives as novel PDE4 inhibitors for the topical treatment of psoriasis Z Song, YY Huang, KQ Hou, L Liu, F Zhou, Y Huang, G Wan, HB Luo, ... Journal of Medicinal Chemistry 65 (5), 4238-4254, 2022 | 19 | 2022 |
| Novel selective and potent EGFR inhibitor that overcomes T790M-Mediated resistance in non-small cell lung cancer Y Li, Z Song, Y Jin, Z Tang, J Kang, X Ma Molecules 21 (11), 1462, 2016 | 13 | 2016 |
| Identification of novel Pyrrolo [2, 3-d] Pyrimidine-based KRAS G12C inhibitors with anticancer effects Z Song, L Lou, G Fan, L Liu, Y Ge, H Liu, ASC Chan, X Zhang, XF Xiong European Journal of Medicinal Chemistry 245, 114907, 2023 | 12 | 2023 |
| Discovery of small molecule Gαq/11 protein inhibitors against uveal melanoma Y Ge, JJ Deng, J Zhu, L Liu, S Ouyang, Z Song, X Zhang, XF Xiong Acta Pharmaceutica Sinica B 12 (8), 3326-3340, 2022 | 11 | 2022 |
| Design, synthesis, and evaluation of small molecule Gαq/11 protein inhibitors for the treatment of uveal melanoma Y Ge, S Shi, JJ Deng, XP Chen, Z Song, L Liu, L Lou, X Zhang, XF Xiong Journal of Medicinal Chemistry 64 (6), 3131-3152, 2021 | 11 | 2021 |
| Demethylative alkylation of methionine residue by employing the sulfonium as the key intermediate QL Hu, JT Liu, J Li, Y Ge, Z Song, ASC Chan, XF Xiong Organic Letters 23 (21), 8543-8548, 2021 | 8 | 2021 |
| Cleavable Cys labeling directed Lys site-selective stapling and single-site modification J Li, QL Hu, Z Song, ASC Chan, XF Xiong Science China Chemistry 65 (7), 1356-1361, 2022 | 6 | 2022 |
| Structure-based optimization of Toddacoumalone as highly potent and selective PDE4 inhibitors with anti-inflammatory effects F Zhou, Y Huang, L Liu, Z Song, KQ Hou, Y Yang, HB Luo, YY Huang, ... Biochemical Pharmacology 202, 115123, 2022 | 5 | 2022 |
| Synthesis and evaluation of imidazo [1, 2-a] pyrazine derivatives as small molecule Gαq/11 inhibitors against uveal melanoma JJ Deng, L Liu, Y Ge, Z Song, J Huang, G Fan, XF Xiong European Journal of Medicinal Chemistry 239, 114520, 2022 | 3 | 2022 |
| Preclinical Evaluation of Azabenzimidazole‐Based PET Radioligands for γ‐8 Dependent Transmembrane AMPA Receptor Regulatory Protein Imaging J Chen, Y Li, Q Yu, JS Patel, X Zhou, K Zhang, J Rong, C Zhao, ... ChemBioChem 25 (6), e202300813, 2024 | 1 | 2024 |
