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Simone Brusco
Simone Brusco
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dCas9-based Scn1a gene activation restores inhibitory interneuron excitability and attenuates seizures in Dravet syndrome mice
G Colasante, G Lignani, S Brusco, C Di Berardino, J Carpenter, ...
Molecular Therapy 28 (1), 235-253, 2020
2042020
The role of nicotinic acetylcholine receptors in autosomal dominant nocturnal frontal lobe epilepsy
A Becchetti, P Aracri, S Meneghini, S Brusco, A Amadeo
Frontiers in physiology 6, 22, 2015
1202015
Frataxin gene editing rescues Friedreich’s ataxia pathology in dorsal root ganglia organoid-derived sensory neurons
Nature Communications, 2020
632020
Nocturnal frontal lobe epilepsy with paroxysmal arousals due to CHRNA2 loss of function
V Conti, P Aracri, L Chiti, S Brusco, F Mari, C Marini, M Albanese, ...
Neurology 84 (15), 1520-1528, 2015
532015
Scn1a gene reactivation after symptom onset rescues pathological phenotypes in a mouse model of Dravet syndrome
N Valassina, S Brusco, A Salamone, L Serra, M Luoni, S Giannelli, S Bido, ...
Nature communications 13 (1), 161, 2022
522022
Postnatal changes in K+/Cl− cotransporter-2 expression in the forebrain of mice bearing a mutant nicotinic subunit linked to sleep-related epilepsy
A Amadeo, A Coatti, P Aracri, M Ascagni, D Iannantuoni, D Modena, ...
Neuroscience 386, 91-107, 2018
192018
Balanced SET levels favor the correct enhancer repertoire during cell fate acquisition
M Zaghi, F Banfi, L Massimino, M Volpin, E Bellini, S Brusco, I Merelli, ...
Nature Communications 14 (1), 3212, 2023
82023
Temporal manipulation of the Scn1a gene reveals its essential role in adult brain function
C Di Berardino, M Mainardi, S Brusco, E Benvenuto, V Broccoli, ...
Brain 147 (4), 1216-1230, 2024
72024
Agonist and antagonist effects of tobacco-related nitrosamines on human α4β2 nicotinic acetylcholine receptors
S Brusco, P Ambrosi, S Meneghini, A Becchetti
Frontiers in Pharmacology 6, 201, 2015
62015
Acid-sensing ion channel 3 is a new potential therapeutic target for the control of glioblastoma cancer stem cells growth
A Balboni, C D’Angelo, N Collura, S Brusco, C Di Berardino, A Targa, ...
Scientific Reports 14 (1), 20421, 2024
2024
Reply: Spatial and temporal manipulation of the Scn1a gene affect adult brain function
C Di Berardino, M Mainardi, S Brusco, E Benvenuto, V Broccoli, ...
Brain 147 (4), e31-e33, 2024
2024
Restoration of Scn1a Expression after Symptom Onset in a Novel Model of Dravet Syndrome Rescues Seizures and Behavioral Alterations
G Colasante, N Valassina, S Brusco, L Serra, A Salamone, G Lignani, ...
MOLECULAR THERAPY 29 (4), 31-31, 2021
2021
Mutant heteromeric nicotinic receptors in brain development and sleep-related epilepsy
S Brusco
Università degli Studi di Milano-Bicocca, 2017
2017
The role of neuronal nicotinic receptors (nAChRs) in the pathogenesis of autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE): a study on wild-type and conditional …
S Meneghini, S Brusco, A Coatti, P Aracri, D Modena, L Carraresi, ...
2017
Expression of the K+/CL-cotransporter KCC2 in a conditional murine model of autosomal dominant nocturnal frontal lobe epilepsy
D Modena, P Aracri, M Ascagni, D Iannantuoni, CE Donati, S Brusco, ...
2016
The role of heteromeric nAChRs in the development of glutamatergic signaling in mice prefrontal cortex.
S Brusco, A Becchetti
Mutant heteromeric nicotinic receptors in brain development and sleep …, 0
The expression of mutant β2-V2878L nAChR subunit does not affect the timing of GABAergic excitatory/inhibitory switch.
S Brusco, A Becchetti
Mutant heteromeric nicotinic receptors in brain development and sleep …, 0
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