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Graham Holloway
Graham Holloway
在 uoguelph.ca 的电子邮件经过验证
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Repeated transient mRNA bursts precede increases in transcriptional and mitochondrial proteins during training in human skeletal muscle
CGR Perry, J Lally, GP Holloway, GJF Heigenhauser, A Bonen, LL Spriet
The Journal of physiology 588 (23), 4795-4810, 2010
6862010
AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: implications for obesity
HM O’Neill, GP Holloway, GR Steinberg
Molecular and cellular endocrinology 366 (2), 135-151, 2013
4932013
One week of bed rest leads to substantial muscle atrophy and induces whole-body insulin resistance in the absence of skeletal muscle lipid accumulation
ML Dirks, BT Wall, B Van De Valk, TM Holloway, GP Holloway, ...
Diabetes 65 (10), 2862-2875, 2016
3852016
Fatty acid transport across the cell membrane: regulation by fatty acid transporters
RW Schwenk, GP Holloway, JJFP Luiken, A Bonen, JFC Glatz
Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) 82 (4-6), 149-154, 2010
3542010
Modest PGC-1α overexpression in muscle in vivo is sufficient to increase insulin sensitivity and palmitate oxidation in subsarcolemmal, not intermyofibrillar, mitochondria
CR Benton, JG Nickerson, J Lally, XX Han, GP Holloway, JFC Glatz, ...
Journal of Biological Chemistry 283 (7), 4228-4240, 2008
2792008
Mitochondrial long chain fatty acid oxidation, fatty acid translocase/CD36 content and carnitine palmitoyltransferase I activity in human skeletal muscle during aerobic exercise
GP Holloway, V Bezaire, GJF Heigenhauser, NN Tandon, JFC Glatz, ...
The Journal of physiology 571 (1), 201-210, 2006
2592006
Exercise training increases sarcolemmal and mitochondrial fatty acid transport proteins in human skeletal muscle
JL Talanian, GP Holloway, LA Snook, GJF Heigenhauser, A Bonen, ...
American Journal of Physiology-Endocrinology and Metabolism 299 (2), E180-E188, 2010
2452010
Skeletal muscle mitochondrial FAT/CD36 content and palmitate oxidation are not decreased in obese women
GP Holloway, AB Thrush, GJF Heigenhauser, NN Tandon, DJ Dyck, ...
American Journal of Physiology-Endocrinology and Metabolism 292 (6), E1782-E1789, 2007
1922007
Omega‐3 supplementation alters mitochondrial membrane composition and respiration kinetics in human skeletal muscle
EAF Herbst, S Paglialunga, C Gerling, J Whitfield, K Mukai, A Chabowski, ...
The Journal of physiology 592 (6), 1341-1352, 2014
1912014
Regulation of skeletal muscle mitochondrial fatty acid metabolism in lean and obese individuals
GP Holloway, A Bonen, LL Spriet
The American journal of clinical nutrition 89 (1), 455S-462S, 2009
1752009
Contribution of FAT/CD36 to the regulation of skeletal muscle fatty acid oxidation: an overview
GP Holloway, J Luiken, JFC Glatz, LL Spriet, A Bonen
Acta physiologica 194 (4), 293-309, 2008
1692008
Increased levels of peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PGC-1α) improve lipid utilisation, insulin signalling and glucose transport in …
CR Benton, GP Holloway, XX Han, Y Yoshida, LA Snook, J Lally, ...
Diabetologia 53, 2008-2019, 2010
1532010
AMPK phosphorylation of ACC2 is required for skeletal muscle fatty acid oxidation and insulin sensitivity in mice
HM O’Neill, JS Lally, S Galic, M Thomas, PD Azizi, MD Fullerton, BK Smith, ...
Diabetologia 57, 1693-1702, 2014
1482014
Beetroot juice supplementation reduces whole body oxygen consumption but does not improve indices of mitochondrial efficiency in human skeletal muscle
J Whitfield, A Ludzki, GJF Heigenhauser, JMG Senden, LB Verdijk, ...
The Journal of physiology 594 (2), 421-435, 2016
1412016
In obese rat muscle transport of palmitate is increased and is channeled to triacylglycerol storage despite an increase in mitochondrial palmitate oxidation
GP Holloway, CR Benton, KL Mullen, Y Yoshida, LA Snook, XX Han, ...
American Journal of Physiology-Endocrinology and Metabolism 296 (4), E738-E747, 2009
1312009
In vivo, fatty acid translocase (CD36) critically regulates skeletal muscle fuel selection, exercise performance, and training-induced adaptation of fatty acid oxidation
JT McFarlan, Y Yoshida, SS Jain, XX Han, LA Snook, J Lally, BK Smith, ...
Journal of Biological Chemistry 287 (28), 23502-23516, 2012
1252012
FAT/CD36 is located on the outer mitochondrial membrane, upstream of long-chain acyl-CoA synthetase, and regulates palmitate oxidation
BK Smith, SS Jain, S Rimbaud, A Dam, J Quadrilatero, R Ventura-Clapier, ...
Biochemical Journal 437 (1), 125-134, 2011
1222011
Nuclear SIRT1 activity, but not protein content, regulates mitochondrial biogenesis in rat and human skeletal muscle
BJ Gurd, Y Yoshida, JT McFarlan, GP Holloway, CD Moyes, ...
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2011
1222011
Negligible direct lactate oxidation in subsarcolemmal and intermyofibrillar mitochondria obtained from red and white rat skeletal muscle
Y Yoshida, GP Holloway, V Ljubicic, H Hatta, LL Spriet, DA Hood, ...
The Journal of physiology 582 (3), 1317-1335, 2007
1192007
In adipose tissue, increased mitochondrial emission of reactive oxygen species is important for short-term high-fat diet-induced insulin resistance in mice
S Paglialunga, A Ludzki, J Root-McCaig, GP Holloway
Diabetologia 58, 1071-1080, 2015
1152015
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