The physiological roles of tau and Aβ: implications for Alzheimer’s disease pathology and therapeutics SA Kent, TL Spires-Jones, CS Durrant Acta neuropathologica 140 (4), 417-447, 2020 | 298 | 2020 |
Lipopolysaccharide-induced neuroinflammation induces presynaptic disruption through a direct action on brain tissue involving microglia-derived interleukin 1 beta O Sheppard, MP Coleman, CS Durrant Journal of neuroinflammation 16, 1-13, 2019 | 140 | 2019 |
Synaptic degeneration in Alzheimer disease M Tzioras, RI McGeachan, CS Durrant, TL Spires-Jones Nature Reviews Neurology 19 (1), 19-38, 2023 | 135 | 2023 |
Synaptophysin depletion and intraneuronal Aβ in organotypic hippocampal slice cultures from huAPP transgenic mice CS Harwell, MP Coleman Molecular neurodegeneration 11, 1-16, 2016 | 63 | 2016 |
Beta secretase 1-dependent amyloid precursor protein processing promotes excessive vascular sprouting through NOTCH3 signalling CS Durrant, K Ruscher, O Sheppard, MP Coleman, I Özen Cell death & disease 11 (2), 98, 2020 | 32 | 2020 |
Interaction between a MAPT variant causing frontotemporal dementia and mutant APP affects axonal transport R Adalbert, S Milde, C Durrant, K Ando, V Stygelbout, Z Yilmaz, S Gould, ... Neurobiology of aging 68, 68-75, 2018 | 21 | 2018 |
Tau assemblies do not behave like independently acting prion-like particles in mouse neural tissue LVC Miller, AS Mukadam, CS Durrant, MJ Vaysburd, T Katsinelos, ... Acta Neuropathologica Communications 9, 1-16, 2021 | 18 | 2021 |
Preparation of organotypic hippocampal slice cultures for the study of CNS disease and damage CS Durrant Axon Degeneration: Methods and Protocols, 133-144, 2020 | 8 | 2020 |
Alzheimer's disease‐like neuropathology in three species of oceanic dolphin MC Vacher, CS Durrant, J Rose, AJ Hall, TL Spires‐Jones, ... European Journal of Neuroscience 57 (7), 1161-1179, 2023 | 6 | 2023 |
p-tau Ser356 is associated with Alzheimer’s disease pathology and is lowered in brain slice cultures using the NUAK inhibitor WZ4003 LW Taylor, EM Simzer, C Pimblett, OTT Lacey-Solymar, RI McGeachan, ... Acta Neuropathologica 147 (1), 7, 2024 | 4* | 2024 |
Protein retention in the endoplasmic reticulum rescues Aβ toxicity in Drosophila JH Catterson, L Minkley, S Aspe, S Judd-Mole, S Moura, MC Dyson, ... Neurobiology of Aging 132, 154-174, 2023 | 2* | 2023 |
Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer’s disease M Colom-Cadena, J Toombs, E Simzer, K Holt, R McGeachan, J Tulloch, ... Acta Neuropathologica 147 (1), 1-22, 2024 | 1 | 2024 |
Evidence for trans-synaptic propagation of oligomeric tau in Progressive Supranuclear Palsy R McGeachan, L Keavey, J Rose, EM Simzer, YY Chang, M Spires-Jones, ... medRxiv, 2022.09.20.22280086, 2024 | 1 | 2024 |
Is amyloid-β a friend or foe? CS Durrant Nature Reviews Molecular Cell Biology, 1-1, 2024 | | 2024 |
Phylogenetic divergence of GABAB receptor signalling in neocortical networks over adult life. MA Wilson, LW Taylor, S Meftah, RI Mcgeachan, T Modebadze, ... bioRxiv, 2024.06. 04.597285, 2024 | | 2024 |
Lowering glucose enhances BACE1 activity and Aβ generation in mouse brain slice cultures O Sheppard, R Humphrey, CS Durrant, MP Coleman bioRxiv, 2024.03. 12.584616, 2024 | | 2024 |
Drosophila appear resistant to trans-synaptic tau propagation JH Catterson, EN Mouofo, I Lopez De Toledo Soler, G Lean, S Dlamini, ... bioRxiv, 2024.03. 11.584446, 2024 | | 2024 |
Opposing roles of physiological and pathological amyloid-β on synapses in live human brain slice cultures RI McGeachan, S Meftah, LW Taylor, JH Catterson, D Negro, J Tulloch, ... bioRxiv, 2024.02. 16.580676, 2024 | | 2024 |
[O3–04–03]: INVESTIGATING PRESYNAPTIC DISRUPTION IN ORGANOTYPIC HIPPOCAMPAL SLICE CULTURES FROM HU‐APP TRANSGENIC MICE CS Durrant, MP Coleman Alzheimer's & Dementia 13 (7S_Part_18), P906-P907, 2017 | | 2017 |
P2‐066: Modelling Synaptic Loss in Organotypic Hippocampal Slices CS Harwell, MP Coleman Alzheimer's & Dementia 12, P633-P633, 2016 | | 2016 |