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Joshua Kaplan
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Structures of the otopetrin proton channels Otop1 and Otop3
K Saotome, B Teng, CC Tsui, WH Lee, YH Tu, JP Kaplan, MSP Sansom, ...
Nature structural & molecular biology 26 (6), 518-525, 2019
682019
Structural motifs for subtype-specific pH-sensitive gating of vertebrate otopetrin proton channels
B Teng, JP Kaplan, Z Liang, Z Krieger, YH Tu, B Burendei, AB Ward, ...
Elife 11, e77946, 2022
242022
Zinc activation of OTOP proton channels identifies structural elements of the gating apparatus
B Teng, JP Kaplan, Z Liang, KS Chyung, MP Goldschen-Ohm, ER Liman
Elife 12, e85317, 2023
102023
Generalizable compositional features influencing the proteostatic fates of polar low-complexity domains
SM Cascarina, JP Kaplan, MR Elder, L Brookbank, ED Ross
International Journal of Molecular Sciences 22 (16), 8944, 2021
22021
Epitope tagging with genome editing in mice reveals that the proton channel OTOP1 is apically localized and not restricted to Type III “sour” taste receptor cells
JP Kaplan, W Ye, H Kileen, A Tran, Z Liang, J Chi, C Yang, P Cohen, ...
Journal of Neuroscience, 2024
2024
Small molecule discovery for modulation of Otopetrin proton channels
B Burendei, J Kaplan, S Forli, ER Liman, AB Ward
Biophysical Journal 122 (3), 522a-523a, 2023
2023
Subtype-specific potentiation of otopetrin proton channels by Zn2+ and its structural basis
JP Kaplan, B Teng, MP Goldschen-Ohm, ER Liman
Biophysical Journal 122 (3), 396a, 2023
2023
Zn2+ potentiation of OTOP proton channels identifies structural elements of the gating apparatus
B Teng, JP Kaplan, Z Liang, M Goldschen-Ohm, ER Liman
bioRxiv, 2022.12. 15.520539, 2022
2022
Subtype-specific gating mechanisms of OTOP channels by protons
B Teng, YH Tu, J Kaplan, Z Liang, Z Krieger, ER Liman
Biophysical Journal 121 (3), 247a, 2022
2022
Epitope Tagging via CRISPR/Cas9 Reveals the Apical Localization of the Sour Receptor OTOP1 in Taste Cells
JP Kaplan, H Kileen, Z Liang, A Tran, J Chi, C Yang, P Cohen, ER Liman
Available at SSRN 4785718, 0
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