STAT3 mediates the differential effects of oncostatin M and TNFα on RA synovial fibroblast and endothelial cell function MM Hanlon, T Rakovich, CC Cunningham, S Ansboro, DJ Veale, ... Frontiers in immunology 10, 2056, 2019 | 78 | 2019 |
Altered metabolic pathways regulate synovial inflammation in rheumatoid arthritis U Fearon, MM Hanlon, SM Wade, JM Fletcher Clinical & Experimental Immunology 197 (2), 170-180, 2019 | 67 | 2019 |
Rheumatoid arthritis CD14+ monocytes display metabolic and inflammatory dysfunction, a phenotype that precedes clinical manifestation of disease T McGarry, MM Hanlon, V Marzaioli, CC Cunningham, V Krishna, ... Clinical & Translational Immunology 10 (1), e1237, 2021 | 60 | 2021 |
Cellular metabolic adaptations in rheumatoid arthritis and their therapeutic implications U Fearon, MM Hanlon, A Floudas, DJ Veale Nature Reviews Rheumatology 18 (7), 398-414, 2022 | 40 | 2022 |
Distinct stromal and immune cell interactions shape the pathogenesis of rheumatoid and psoriatic arthritis A Floudas, CM Smith, O Tynan, N Neto, V Krishna, SM Wade, M Hanlon, ... Annals of the Rheumatic Diseases 81 (9), 1224-1242, 2022 | 31 | 2022 |
Canagliflozin impairs T cell effector function via metabolic suppression in autoimmunity BJ Jenkins, J Blagih, FM Ponce-Garcia, M Canavan, N Gudgeon, ... Cell Metabolism 35 (7), 1132-1146. e9, 2023 | 30 | 2023 |
Metabolites as drivers and targets in rheumatoid arthritis MM Hanlon, M Canavan, BE Barker, U Fearon Clinical and Experimental Immunology 208 (2), 167-180, 2022 | 29 | 2022 |
Rheumatoid arthritis macrophages are primed for inflammation and display bioenergetic and functional alterations MM Hanlon, T McGarry, V Marzaioli, S Amaechi, Q Song, S Nagpal, ... Rheumatology, 2022 | 19 | 2022 |
Targeting JAK-STAT signalling alters PsA synovial fibroblast pro-inflammatory and metabolic function A O’Brien, MM Hanlon, V Marzaioli, SC Wade, K Flynn, U Fearon, ... Frontiers in Immunology 12, 672461, 2021 | 19 | 2021 |
CD200+ fibroblasts form a pro-resolving mesenchymal network in arthritis S Rauber, H Mohammadian, C Schmidkonz, A Atzinger, A Soare, ... Nature Immunology 25 (4), 682-692, 2024 | 9 | 2024 |
The mammalian target of rapamycin contributes to synovial fibroblast pathogenicity in rheumatoid arthritis BE Barker, MM Hanlon, V Marzaioli, CM Smith, CC Cunningham, ... Frontiers in Medicine 10, 1029021, 2023 | 5 | 2023 |
STAT3 mediates the differential effects of Oncostatin M and TNFalpha on RA synovial fibroblast and endothelial cell function. Front Immunol. 2019; 10: 2056 MM Hanlon, T Rakovich, CC Cunningham, S Ansboro, DJ Veale, ... | 5 | 2019 |
P022/O02 Distinct macrophage phenotype and bioenergetic profiles in rheumatoid arthritis MM Hanlon, T McGarry, M Canavan, C Low, DJ Veale, U Fearon Annals of the Rheumatic Diseases 78 (Suppl 1), A8-A8, 2019 | 2 | 2019 |
OP0028 CD206+ CD163+ PATHOGENIC MACROPHAGES ENRICHED IN RHEUMATOID ARTHRITIS SYNOVIAL TISSUE WITH DISTINCT TRANSCRIPTIONAL SIGNATURES M Hanlon, M Canavan, Q Song, N Neto, P Gallagher, R Mullan, C Hurson, ... Annals of the Rheumatic Diseases 80 (Suppl 1), 15-15, 2021 | 1 | 2021 |
Loss of synovial tissue macrophage homeostasis precedes rheumatoid arthritis clinical onset MM Hanlon, CM Smith, M Canavan, NGB Neto, Q Song, MJ Lewis, ... Science Advances 10 (39), eadj1252, 2024 | | 2024 |
RA Monocytes and Monocyte-Derived Macrophages Display Heightened Inflammatory Responses, Reduced Endocytic Capacity and Distinct TET Expression Compared to PsA Monocytes S Amaechi, M Hanlon, A Gilmore, D Anton, M Canavan, S Sundanum, ... ARTHRITIS & RHEUMATOLOGY 75, 94-95, 2023 | | 2023 |
Molecular reframing of fibroblasts during resolution of arthritis A Ramming, S Rauber, H Mohammadian, C Schmidkonz, A Atzinger, ... | | 2023 |
T Cell and Macrophage Synergy Drive Inflammatory Synovial Fibroblasts in Rheumatoid but Not Psoriatic Arthritis A Floudas, C Smith, O Tynan, N Neto, K Vinod, S Wade, M Hanlon, ... ARTHRITIS & RHEUMATOLOGY 74, 997-999, 2022 | | 2022 |
Molecular Interplay Between Mammalian Target of Rapamycin (mTOR) and the YAP Pathway Mediates Rheumatoid Arthritis Synovial Fibroblast Activation B Barker, M Hanlon, S Wade, D Veale, U Fearon, M Canavan ARTHRITIS & RHEUMATOLOGY 74, 1131-1133, 2022 | | 2022 |
POS0419 DIFFERENTIAL miRNA EXPRESSION AND ENDOTHELIAL CELL FUNCTION IN RHEUMATOID ARTHRITIS AND PSORIATIC ARTHRITIS O Tynan, C Cunningham, M Hanlon, A Floudas, M Canavan, U Fearon, ... Annals of the Rheumatic Diseases 81 (Suppl 1), 464-465, 2022 | | 2022 |