关注
Alina Guna
Alina Guna
K99/R00 Pathway to Independence Fellow
在 caltech.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
The ER membrane protein complex is a transmembrane domain insertase
A Guna, N Volkmar, JC Christianson, RS Hegde
Science 359 (6374), 470-473, 2018
2782018
Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq
JM Replogle, RA Saunders, AN Pogson, JA Hussmann, A Lenail, A Guna, ...
Cell 185 (14), 2559-2575. e28, 2022
2612022
EMC is required to initiate accurate membrane protein topogenesis
PJ Chitwood, S Juszkiewicz, A Guna, S Shao, RS Hegde
Cell 175 (6), 1507-1519. e16, 2018
2122018
Transmembrane domain recognition during membrane protein biogenesis and quality control
A Guna, RS Hegde
Current Biology 28 (8), R498-R511, 2018
1132018
Comparative mapping of the 22q11. 2 deletion region and the potential of simple model organisms
A Guna, NJ Butcher, AS Bassett
Journal of Neurodevelopmental Disorders 7 (1), 1-16, 2015
1102015
A highly porous metal-organic framework system to deliver payloads for gene knockdown
MH Teplensky, M Fantham, C Poudel, C Hockings, M Lu, A Guna, ...
Chem 5 (11), 2926-2941, 2019
792019
Response to clozapine in a clinically identifiable subtype of schizophrenia
NJ Butcher, WLA Fung, L Fitzpatrick, A Guna, DM Andrade, AE Lang, ...
The British Journal of Psychiatry 206 (6), 484-491, 2015
782015
Elucidating the diagnostic odyssey of 22q11. 2 deletion syndrome
LD Palmer, NJ Butcher, E Boot, KA Hodgkinson, T Heung, EWC Chow, ...
American Journal of Medical Genetics Part A 176 (4), 936-944, 2018
692018
MTCH2 is a mitochondrial outer membrane protein insertase
A Guna, TA Stevens, AJ Inglis, JM Replogle, TK Esantsi, G Muthukumar, ...
Science 378 (6617), 317-322, 2022
592022
Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology
A Stangherlin, DCS Wong, S Barbiero, JL Watson, A Zeng, E Seinkmane, ...
Nature Communications 12, 2021
372021
Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors
JM Replogle, JL Bonnar, AN Pogson, CR Liem, NK Maier, Y Ding, ...
Elife 11, e81856, 2022
352022
WNK1 is an assembly factor for the human ER membrane protein complex
T Pleiner, M Hazu, GP Tomaleri, K Januszyk, RS Oania, MJ Sweredoski, ...
Molecular cell 81 (13), 2693-2704. e12, 2021
342021
Differential modes of orphan subunit recognition for the WRB/CAML complex
AJ Inglis, KR Page, A Guna, RM Voorhees
Cell Reports 30 (11), 3691-3698. e5, 2020
282020
Macromolecular condensation buffers intracellular water potential
JL Watson, E Seinkmane, CT Styles, A Mihut, LK Krüger, KE McNally, ...
Nature 623 (7988), 842-852, 2023
272023
Coupled protein quality control during nonsense-mediated mRNA decay
AJ Inglis, A Guna, Á Gálvez-Merchán, A Pal, TK Esantsi, HR Keys, ...
Journal of Cell Science 136 (10), jcs261216, 2023
162023
A genome-wide optical pooled screen reveals regulators of cellular antiviral responses
RJ Carlson, MD Leiken, A Guna, N Hacohen, PC Blainey
Proceedings of the National Academy of Sciences 120 (16), e2210623120, 2023
142023
A TAle of two pathways: Tail-anchored protein insertion at the endoplasmic reticulum
A Guna, M Hazu, GP Tomaleri, RM Voorhees
Cold Spring Harbor Perspectives in Biology 15 (3), a041252, 2023
92023
A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens
A Guna, KR Page, JM Replogle, TK Esantsi, ML Wang, JS Weissman, ...
BMC genomics 24 (1), 651, 2023
52023
Triaging of α-helical proteins to the mitochondrial outer membrane by distinct chaperone machinery based on substrate topology
G Muthukumar, TA Stevens, AJ Inglis, TK Esantsi, RA Saunders, F Schulte, ...
Molecular Cell, 2024
12024
Role of a holo-insertase complex in the biogenesis of biophysically diverse ER membrane proteins
KR Page, VN Nguyen, T Pleiner, GP Tomaleri, ML Wang, A Guna, ...
bioRxiv, 2023.11. 28.569054, 2023
12023
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