Cre–loxP biochemistry K Ghosh, GD Van Duyne Methods 28 (3), 374-383, 2002 | 162 | 2002 |
Requirements for catalysis in the Cre recombinase active site B Gibb, K Gupta, K Ghosh, R Sharp, J Chen, GD Van Duyne Nucleic acids research 38 (17), 5817-5832, 2010 | 97 | 2010 |
Peptide trapping of the Holliday junction intermediate in Cre-loxP site-specific recombination K Ghosh, CK Lau, F Guo, AM Segall, GD Van Duyne Journal of Biological Chemistry 280 (9), 8290-8299, 2005 | 69 | 2005 |
Synapsis of loxP sites by Cre recombinase K Ghosh, F Guo, GD Van Duyne Journal of Biological Chemistry 282 (33), 24004-24016, 2007 | 65 | 2007 |
Preferential synapsis of loxP sites drives ordered strand exchange in Cre-loxP site-specific recombination K Ghosh, CK Lau, K Gupta, GD Van Duyne Nature chemical biology 1 (5), 275-282, 2005 | 58 | 2005 |
Crystal structure of rat intestinal alkaline phosphatase–role of crown domain in mammalian alkaline phosphatases K Ghosh, DM Tagore, R Anumula, B Lakshmaiah, P Kumar, S Singaram, ... Journal of structural biology 184 (2), 182-192, 2013 | 49 | 2013 |
Synthesis, Structure–Activity Relationships, and In Vivo Evaluation of Novel Tetrahydropyran-Based Thiodisaccharide Mimics as Galectin-3 Inhibitors L Xu, RA Hartz, BR Beno, K Ghosh, JK Shukla, A Kumar, D Patel, ... Journal of Medicinal Chemistry, 2021 | 20 | 2021 |
Development of a RapidFire mass spectrometry assay and a fluorescence assay for the discovery of kynurenine aminotransferase II inhibitors to treat central nervous system disorders H Lu, L Kopcho, K Ghosh, M Witmer, M Parker, S Gupta, M Paul, ... Analytical biochemistry 501, 56-65, 2016 | 17 | 2016 |
The discovery of a pan-genotypic, primer grip inhibitor of HCV NS5B polymerase KJ Eastman, K Parcella, KS Yeung, KA Grant-Young, J Zhu, T Wang, ... MedChemComm 8 (4), 796-806, 2017 | 16 | 2017 |
A comparative three-dimensional model of the carboxy-terminal domain of the lambda repressor and its use to build intact repressor tetramer models bound to adjacent operator sites R Chattopadhyaya, K Ghosh Journal of structural biology 141 (2), 103-114, 2003 | 10 | 2003 |
pH-dependent autocleavage of lambda repressor occurs in the operator-bound form: characterization of lambda repressor autocleavage K Ghosh, PAL Atasi, R Chattopadhyaya Biochemical Journal 379 (2), 325-330, 2004 | 9 | 2004 |
Characterization of recombinantly expressed rat and monkey intestinal alkaline phosphatases: in vitro studies and in vivo correlations M Subramanian, S Paruchury, S Singh, SP Singh, R Arla, S Pahwa, ... Drug Metabolism and Disposition, dmd. 113.051987, 2013 | 7 | 2013 |
Expression and characterization of cynomolgus monkey cytochrome CYP3A4 in a novel human embryonic kidney (HEK293) cell based mammalian system S Selvakumar, P Bhutani, K Ghosh, P Krishnamurthy, S Kallipatti, ... Drug Metabolism and Disposition, dmd. 113.055491, 2013 | 6 | 2013 |
Papain does not cleave operator-bound lambda repressor: Structural characterization of the carboxy terminal domain and the hinge K Ghosh, R Chattopadhyaya Journal of Biomolecular Structure and Dynamics 18 (4), 557-567, 2001 | 4 | 2001 |
The mechanism of asymmetric strand exchange in Cre-loxP site-specific recombination G Van Duyne, K Ghosh The FASEB Journal 21 (5), A44-A44, 2007 | 1 | 2007 |
A structural model for the Cre-loxP site-specific recombination pathway GD Van Duyne, F Guo, D Gopaul, K Ghosh Faseb Journal 15 (5), A1155-A1155, 2001 | 1 | 2001 |
Discovery of BMS-986160 as a second-generation inhibitor of the hepatitis C virus NS3/4A with pan-genotypic antiviral activity LQ Sun, E Mull, S Kandhasamy, VR Baratam, S Puttaswamy, N Pulicharla, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |
Second-generation inhibitors of the hepatitis C virus NS3/4A protease: Discovery of BMS-986144 with pan-genotypic antiviral activity LQ Sun, E Mull, Q Zhao, E Gillis, M Bowsher, S D'Andrea, Z Zheng, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 254, 2017 | | 2017 |
EXPRESSION AND CHARACTERIZATION OF CYNOMOLGUS CYTOCHROME P450 3A4 M Subramanian, P Bhutani, S Selvakumar, K Ghosh, P Krishnamurthy, ... DRUG METABOLISM REVIEWS 45, 89-89, 2014 | | 2014 |