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Nicholas James Ashton
Nicholas James Ashton
University of Gothenburg / King's College London
在 gu.se 的电子邮件经过验证
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Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts
TK Karikari, TA Pascoal, NJ Ashton, S Janelidze, AL Benedet, ...
The Lancet Neurology 19 (5), 422-433, 2020
8922020
Plasma p-tau231: a new biomarker for incipient Alzheimer’s disease pathology
NJ Ashton, TA Pascoal, TK Karikari, AL Benedet, J Lantero-Rodriguez, ...
Acta neuropathologica 141, 709-724, 2021
3982021
Neurochemical evidence of astrocytic and neuronal injury commonly found in COVID-19
N Kanberg, NJ Ashton, LM Andersson, A Yilmaz, M Lindh, S Nilsson, ...
Neurology 95 (12), e1754-e1759, 2020
3922020
Microglial activation and tau propagate jointly across Braak stages
TA Pascoal, AL Benedet, NJ Ashton, MS Kang, J Therriault, M Chamoun, ...
Nature medicine 27 (9), 1592-1599, 2021
3082021
Steroid‐responsive encephalitis in coronavirus disease 2019
A Pilotto, S Odolini, S Masciocchi, A Comelli, I Volonghi, S Gazzina, ...
Annals of neurology 88 (2), 423-427, 2020
3032020
A multicentre validation study of the diagnostic value of plasma neurofilament light
NJ Ashton, S Janelidze, A Al Khleifat, A Leuzy, EL van der Ende, ...
Nature communications 12 (1), 3400, 2021
2972021
Plasma GFAP is an early marker of amyloid-β but not tau pathology in Alzheimer’s disease
JB Pereira, S Janelidze, R Smith, N Mattsson-Carlgren, S Palmqvist, ...
Brain 144 (11), 3505-3516, 2021
2682021
Plasma p-tau181 accurately predicts Alzheimer’s disease pathology at least 8 years prior to post-mortem and improves the clinical characterisation of cognitive decline
J Lantero Rodriguez, TK Karikari, M Suárez-Calvet, C Troakes, A King, ...
Acta neuropathologica 140, 267-278, 2020
2602020
Differences between plasma and cerebrospinal fluid glial fibrillary acidic protein levels across the Alzheimer disease continuum
AL Benedet, M Milà-Alomà, A Vrillon, NJ Ashton, TA Pascoal, F Lussier, ...
JAMA neurology 78 (12), 1471-1483, 2021
2592021
Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer’s continuum when only subtle changes in Aβ …
M Suárez‐Calvet, TK Karikari, NJ Ashton, J Lantero Rodriguez, ...
EMBO molecular medicine 12 (12), e12921, 2020
2552020
Diagnostic performance and prediction of clinical progression of plasma phospho-tau181 in the Alzheimer’s Disease Neuroimaging Initiative
TK Karikari, AL Benedet, NJ Ashton, J Lantero Rodriguez, A Snellman, ...
Molecular psychiatry 26 (2), 429-442, 2021
2452021
Plasma proteins predict conversion to dementia from prodromal disease
A Hye, J Riddoch-Contreras, AL Baird, NJ Ashton, C Bazenet, R Leung, ...
Alzheimer's & Dementia 10 (6), 799-807. e2, 2014
2442014
The diagnostic and prognostic capabilities of plasma biomarkers in Alzheimer's disease
J Simrén, A Leuzy, TK Karikari, A Hye, AL Benedet, J Lantero‐Rodriguez, ...
Alzheimer's & Dementia 17 (7), 1145-1156, 2021
2172021
Plasma p-tau231 and p-tau217 as state markers of amyloid-β pathology in preclinical Alzheimer’s disease
M Milà-Alomà, NJ Ashton, M Shekari, G Salvadó, P Ortiz-Romero, ...
Nature Medicine 28 (9), 1797-1801, 2022
2102022
Biomarkers for tau pathology
M Schöll, A Maass, N Mattsson, NJ Ashton, K Blennow, H Zetterberg, ...
Molecular and Cellular Neuroscience 97, 18-33, 2019
2092019
Longitudinal associations of blood phosphorylated Tau181 and neurofilament light chain with neurodegeneration in Alzheimer disease
A Moscoso, MJ Grothe, NJ Ashton, TK Karikari, JL Rodríguez, A Snellman, ...
JAMA neurology 78 (4), 396-406, 2021
1882021
Time course of phosphorylated-tau181 in blood across the Alzheimer’s disease spectrum
A Moscoso, MJ Grothe, NJ Ashton, TK Karikari, JL Rodriguez, A Snellman, ...
Brain 144 (1), 325-339, 2021
1702021
Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer’s disease
S Janelidze, D Bali, NJ Ashton, NR Barthélemy, J Vanbrabant, E Stoops, ...
Brain 146 (4), 1592-1601, 2023
1682023
Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer’s trial selection and disease monitoring
NJ Ashton, S Janelidze, N Mattsson-Carlgren, AP Binette, O Strandberg, ...
Nature medicine 28 (12), 2555-2562, 2022
1642022
An update on blood-based biomarkers for non-Alzheimer neurodegenerative disorders
NJ Ashton, A Hye, AP Rajkumar, A Leuzy, S Snowden, M Suárez-Calvet, ...
Nature Reviews Neurology 16 (5), 265-284, 2020
1592020
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