Revisiting the resazurin-based sensing of cellular viability: Widening the application horizon D Lavogina, H Lust, MJ Tahk, T Laasfeld, H Vellama, N Nasirova, ... Biosensors 12 (4), 196, 2022 | 75 | 2022 |
The constitutive activity of melanocortin‐4 receptors in cAMP pathway is allosterically modulated by zinc and copper ions R Link, S Veiksina, MJ Tahk, T Laasfeld, P Paiste, S Kopanchuk, A Rinken Journal of neurochemistry 153 (3), 346-361, 2020 | 20 | 2020 |
Structure-Based Design of High-Affinity Fluorescent Probes for the Neuropeptide Y Y1 Receptor C Müller, J Gleixner, MJ Tahk, S Kopanchuk, T Laasfeld, M Weinhart, ... Journal of Medicinal Chemistry 65 (6), 4832-4853, 2022 | 15 | 2022 |
Budded baculoviruses as a receptor display system to quantify ligand binding with TIRF microscopy T Laasfeld, R Ehrminger, MJ Tahk, S Veiksina, KR Kolvart, M Min, ... Nanoscale 13 (4), 2436-2447, 2021 | 14 | 2021 |
BRET-and fluorescence anisotropy-based assays for real-time monitoring of ligand binding to M2 muscarinic acetylcholine receptors L Grätz, T Laasfeld, A Allikalt, CG Gruber, A Pegoli, MJ Tahk, ML Tsernant, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1868 (3), 118930, 2021 | 13 | 2021 |
Fluorescence Anisotropy-Based Assay for Characterization of Ligand Binding Dynamics to GPCRs: The Case of Cy3B-Labeled Ligands Binding to MC4 Receptors … S Veiksina, MJ Tahk, T Laasfeld, R Link, S Kopanchuk, A Rinken G protein-coupled receptor screening assays: methods and protocols, 119-136, 2021 | 9 | 2021 |
ArtSeg—Artifact segmentation and removal in brightfield cell microscopy images without manual pixel-level annotations MAS Ali, K Hollo, T Laasfeld, J Torp, MJ Tahk, A Rinken, K Palo, L Parts, ... Scientific Reports 12 (1), 11404, 2022 | 8 | 2022 |
Live-cell microscopy or fluorescence anisotropy with budded baculoviruses—which way to go with measuring ligand binding to M4 muscarinic receptors? MJ Tahk, J Torp, MAS Ali, D Fishman, L Parts, L Grätz, C Müller, M Keller, ... Open Biology 12 (6), 220019, 2022 | 7 | 2022 |
Illuminating Neuropeptide Y Y4 Receptor Binding: Fluorescent Cyclic Peptides with Subnanomolar Binding Affinity as Novel Molecular Tools J Gleixner, S Kopanchuk, L Grätz, MJ Tahk, T Laasfeld, S Veikšina, ... ACS Pharmacology & Translational Science 7 (4), 1142-1168, 2024 | 3 | 2024 |
Fluorescence based HTS-compatible ligand binding assays for dopamine D3 receptors in baculovirus preparations and live cells MJ Tahk, T Laasfeld, E Meriste, J Brea, MI Loza, M Majellaro, M Contino, ... Frontiers in Molecular Biosciences 10, 1119157, 2023 | 2 | 2023 |
UT-GPCR001 microscopy of ligand binding to M4 muscarinic receptor in live CHO-K1-hM4 cells MJ Tahk, J Torp, MAS Ali, D Fishman, L Parts, L Grätz, C Müller, M Keller, ... University of Tartu, Institute of Chemistry, Chair of Bioorganic chemistry, 2022 | 2 | 2022 |
cAMP Biosensor Assay Using BacMam Expression System: Studying the Downstream Signaling of LH/hCG Receptor Activation D Lavogina, T Laasfeld, MJ Tahk, O Kukk, A Allikalt, S Kopanchuk, ... G Protein-Coupled Receptor Screening Assays: Methods and Protocols, 179-192, 2021 | 2 | 2021 |
MultiBacMam Technology for Studying the Downstream cAMP Signaling Pathway of M2 Muscarinic Acetylcholine Receptor A Allikalt, S Veiksina, MJ Tahk, E Vavers, E Laaneväli, A Rinken, ... Muscarinic Receptor: From Structure to Animal Models, 153-175, 2024 | 1 | 2024 |
ArtSeg: rapid artifact segmentation and removal in brightfield cell microscopy images MAS Ali, K Hollo, T Laasfeld, J Torp, MJ Tahk, A Rinken, K Palo, L Parts, ... bioRxiv, 2022.01. 24.477467, 2022 | 1 | 2022 |
Dually Labeled Neurotensin NTS1R Ligands for Probing Radiochemical and Fluorescence-Based Binding Assays FJ Ertl, S Kopanchuk, NC Dijon, S Veikšina, MJ Tahk, T Laasfeld, ... Journal of Medicinal Chemistry 67 (18), 16664-16691, 2024 | | 2024 |
Exploring Muscarinic Acetylcholine Receptor Binding Kinetics with Fluorescence Anisotropy T Laasfeld, MJ Tahk, A Allikalt, J Torp, L Grätz, S Kopanchuk, A Rinken Muscarinic Receptor: From Structure to Animal Models, 113-151, 2024 | | 2024 |
ArtSeg-CHO-M4R: artifact segmentation in microscopy of ligand binding to M4 muscarinic receptor in live CHO-K1-hM4 cells. MAS Ali, K Hollo, T Laasfeld, J Torp, MJ Tahk, A Rinken, K Palo, L Parts, ... University of Tartu, Institute of Computer Sciences, 2022 | | 2022 |
UT-GPCR004 CHO-K1 cell line bright-field and fluorescence microscopy and corresponding segmentation ground truth MJ Tahk, J Torp, MAS Ali, D Fishman, L Parts, L Grätz, C Müller, M Keller, ... University of Tartu, Institute of Chemistry, Chair of Bioorganic chemistry, 2022 | | 2022 |
UT-GPCR002 Machine learning models for CHO-K1 cell segmentation from fluorescence and bright-field microscopy images MJ Tahk, J Torp, MAS Ali, D Fishman, L Parts, L Grätz, C Müller, M Keller, ... University of Tartu, Institute of Chemistry, Chair of Bioorganic chemistry, 2022 | | 2022 |
UT-GPCR003 Fluorescence anisotropy and microscopy measurements experimental metadata of ligand binding to M4 muscarinic receptors MJ Tahk, J Torp, MAS Ali, D Fishman, L Parts, L Grätz, C Müller, M Keller, ... University of Tartu, Institute of Chemistry, Chair of Bioorganic chemistry, 2022 | | 2022 |