APP intracellular domain derived from amyloidogenic β-and γ-secretase cleavage regulates neprilysin expression MO Grimm, J Mett, CP Stahlmann, S Grösgen, VJ Haupenthal, T Blümel, ... Frontiers in aging neuroscience 7, 77, 2015 | 90 | 2015 |
Oxidized docosahexaenoic acid species and lipid peroxidation products increase amyloidogenic amyloid precursor protein processing MOW Grimm, VJ Haupenthal, J Mett, CP Stahlmann, T Blümel, ... Neurodegenerative Diseases 16 (1-2), 44-54, 2016 | 66 | 2016 |
Modulating hinge flexibility in the APP transmembrane domain alters γ-secretase cleavage A Götz, N Mylonas, P Högel, M Silber, H Heinel, S Menig, A Vogel, ... Biophysical journal 116 (11), 2103-2120, 2019 | 47 | 2019 |
Stabilization/destabilization of the APP transmembrane domain by mutations in the di-glycine hinge alter helical structure and dynamics, and impair cleavage by γ-secretase A Götz, N Mylonas, P Högel, M Silber, H Heinel, S Menig, A Vogel, ... bioRxiv, 375006, 2018 | 3 | 2018 |