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Irene Bertolini
Irene Bertolini
在 wistar.org 的电子邮件经过验证 - 首页
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Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
JA Welsh, DCI Goberdhan, L O'Driscoll, EI Buzas, C Blenkiron, ...
Journal of extracellular vesicles 13 (2), e12404, 2024
9562024
Mitochondrial Akt regulation of hypoxic tumor reprogramming
YC Chae, V Vaira, MC Caino, HY Tang, JH Seo, AV Kossenkov, ...
Cancer cell 30 (2), 257-272, 2016
2102016
The vacuolar H+ ATPase is a novel therapeutic target for glioblastoma
A Di Cristofori, S Ferrero, I Bertolini, G Gaudioso, MV Russo, V Berno, ...
Oncotarget 6 (19), 17514, 2015
782015
The mitophagy effector FUNDC1 controls mitochondrial reprogramming and cellular plasticity in cancer cells
J Li, E Agarwal, I Bertolini, JH Seo, MC Caino, JC Ghosh, AV Kossenkov, ...
Science signaling 13 (642), eaaz8240, 2020
712020
A GBM-like V-ATPase signature directs cell-cell tumor signaling and reprogramming via large oncosomes
I Bertolini, A Terrasi, C Martelli, G Gaudioso, A Di Cristofori, AM Storaci, ...
EBioMedicine 41, 225-235, 2019
442019
Small extracellular vesicle regulation of mitochondrial dynamics reprograms a hypoxic tumor microenvironment
I Bertolini, JC Ghosh, AV Kossenkov, S Mulugu, SR Krishn, V Vaira, J Qin, ...
Developmental cell 55 (2), 163-177. e6, 2020
372020
IDH2 reprograms mitochondrial dynamics in cancer through a HIF-1α–regulated pseudohypoxic state
Y Wang, E Agarwal, I Bertolini, JC Ghosh, JH Seo, DC Altieri
The FASEB Journal 33 (12), 13398, 2019
352019
Myc regulation of a mitochondrial trafficking network mediates tumor cell invasion and metastasis
E Agarwal, BJ Altman, J Ho Seo, I Bertolini, JC Ghosh, A Kaur, ...
Molecular and cellular biology 39 (14), e00109-19, 2019
312019
Specific V-ATPase expression sub-classifies IDHwt lower-grade gliomas and impacts glioma growth in vivo
A Terrasi, I Bertolini, C Martelli, G Gaudioso, A Di Cristofori, AM Storaci, ...
EBioMedicine 41, 214-224, 2019
282019
Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability
JC Ghosh, M Perego, E Agarwal, I Bertolini, Y Wang, AR Goldman, ...
Proceedings of the National Academy of Sciences 119 (8), e2115624119, 2022
252022
V-ATPase controls tumor growth and autophagy in a Drosophila model of gliomagenesis
M Formica, AM Storaci, I Bertolini, F Carminati, H Knaevelsrud, V Vaira, ...
Autophagy 17 (12), 4442-4452, 2021
132021
NFκB activation by hypoxic small extracellular vesicles drives oncogenic reprogramming in a breast cancer microenvironment
I Bertolini, M Perego, JC Ghosh, AV Kossenkov, DC Altieri
Oncogene 41 (17), 2520-2525, 2022
112022
HSP70-mediated mitochondrial dynamics and autophagy represent a novel vulnerability in pancreatic cancer
GDS Ferretti, CE Quaas, I Bertolini, A Zuccotti, O Saatci, JA Kashatus, ...
Cell Death & Differentiation, 1-16, 2024
92024
Interplay Between V-ATPase G1 and Small EV-miRNAs Modulates ERK1/2 Activation in GBM Stem Cells and Nonneoplastic Milieu
I Bertolini, AM Storaci, A Terrasi, AD Cristofori, M Locatelli, M Caroli, ...
Molecular Cancer Research 18 (11), 1744-1754, 2020
72020
Protocol for assessing real-time changes in mitochondrial morphology, fission and fusion events in live cells using confocal microscopy
I Bertolini, F Keeney, DC Altieri
STAR protocols 2 (3), 100767, 2021
62021
Intercellular HIF1α reprograms mammary progenitors and myeloid immune evasion to drive high-risk breast lesions
I Bertolini, M Perego, Y Nefedova, C Lin, A Milcarek, P Vogel, JC Ghosh, ...
The Journal of Clinical Investigation 133 (8), 2023
52023
Parkin activates innate immunity and promotes antitumor immune responses
M Perego, M Yeon, E Agarwal, AT Milcarek, I Bertolini, C Camisaschi, ...
The Journal of Clinical Investigation 134 (22), 2024
32024
Syntaphilin regulates neutrophil migration in cancer
S Fu, H Deng, I Bertolini, M Perego, ES Chen, E Sanseviero, A Mostafa, ...
Cancer immunology research 11 (3), 278-289, 2023
32023
Parkin ubiquitination of Kindlin-2 enables mitochondria-associated metastasis suppression
M Yeon, I Bertolini, E Agarwal, JC Ghosh, HY Tang, DW Speicher, ...
Journal of Biological Chemistry 299 (6), 2023
22023
V-ATPase in glioma stem cells: a novel metabolic vulnerability
AM Storaci, I Bertolini, C Martelli, G De Turris, N Mansour, M Crosti, ...
Journal of Experimental & Clinical Cancer Research 44 (1), 1-14, 2025
2025
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