| Copper active sites in biology EI Solomon, DE Heppner, EM Johnston, JW Ginsbach, J Cirera, ... Chemical reviews 114 (7), 3659-3853, 2014 | 1573 | 2014 |
| A quantitative tissue-specific landscape of protein redox regulation during aging H Xiao, MP Jedrychowski, DK Schweppe, EL Huttlin, Q Yu, DE Heppner, ... Cell 180 (5), 968-983. e24, 2020 | 275 | 2020 |
| Single and dual targeting of mutant EGFR with an allosteric inhibitor C To, J Jang, T Chen, E Park, M Mushajiang, DJH De Clercq, M Xu, ... Cancer discovery 9 (7), 926-943, 2019 | 249 | 2019 |
| Copper dioxygen (bio) inorganic chemistry EI Solomon, JW Ginsbach, DE Heppner, MT Kieber-Emmons, ... Faraday discussions 148, 11-39, 2011 | 196 | 2011 |
| Reaction coordinate of a functional model of tyrosinase: spectroscopic and computational characterization BT Op’t Holt, MA Vance, LM Mirica, DE Heppner, TDP Stack, EI Solomon Journal of the American Chemical Society 131 (18), 6421-6438, 2009 | 128 | 2009 |
| Direct cysteine sulfenylation drives activation of the Src kinase DE Heppner, CM Dustin, C Liao, M Hristova, C Veith, AC Little, BA Ahlers, ... Nature communications 9 (1), 4522, 2018 | 109 | 2018 |
| Redox-dependent regulation of epidermal growth factor receptor signaling DE Heppner, A van der Vliet Redox Biology 8, 24-27, 2016 | 79 | 2016 |
| DUOX1 mediates persistent epithelial EGFR activation, mucous cell metaplasia, and airway remodeling during allergic asthma A Habibovic, M Hristova, DE Heppner, K Danyal, JL Ather, ... JCI insight 1 (18), 2016 | 76 | 2016 |
| An allosteric inhibitor against the therapy-resistant mutant forms of EGFR in non-small cell lung cancer C To, TS Beyett, J Jang, WW Feng, M Bahcall, HM Haikala, BH Shin, ... Nature Cancer 3 (4), 402-417, 2022 | 75 | 2022 |
| Cysteine perthiosulfenic acid (Cys-SSOH): A novel intermediate in thiol-based redox signaling? DE Heppner, M Hristova, T Ida, A Mijuskovic, CM Dustin, V Bogdándi, ... Redox biology 14, 379-385, 2018 | 72 | 2018 |
| Dual oxidase: a novel therapeutic target in allergic disease A van der Vliet, K Danyal, DE Heppner British journal of pharmacology 175 (9), 1401-1418, 2018 | 65 | 2018 |
| DUOX1 silencing in lung cancer promotes EMT, cancer stem cell characteristics and invasive properties AC Little, D Sham, M Hristova, K Danyal, DE Heppner, RA Bauer, ... Oncogenesis, e261, 2016 | 64 | 2016 |
| Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors DJH De Clercq, DE Heppner, C To, J Jang, E Park, CH Yun, ... ACS Medicinal Chemistry Letters 10 (11), 1549-1553, 2019 | 63 | 2019 |
| The NADPH Oxidases DUOX1 and NOX2 Play Distinct Roles in Redox Regulation of Epidermal Growth Factor Receptor Signaling DE Heppner, M Hristova, CM Dustin, K Danyal, A Habibovic, ... Journal of Biological Chemistry 291 (44), 23282, 2016 | 60 | 2016 |
| Mechanism of the reduction of the native intermediate in the multicopper oxidases: Insights into rapid intramolecular electron transfer in turnover DE Heppner, CH Kjaergaard, EI Solomon Journal of the American Chemical Society 136 (51), 17788-17801, 2014 | 60 | 2014 |
| Redox regulation of tyrosine kinase signalling: more than meets the eye CM Dustin, DE Heppner, MCJ Lin, A van der Vliet The Journal of Biochemistry 167 (2), 151-163, 2020 | 54 | 2020 |
| The role of sulfenic acids in cellular redox signaling: Reconciling chemical kinetics and molecular detection strategies DE Heppner, YMW Janssen-Heininger, A van der Vliet Archives of Biochemistry and Biophysics 616, 40-46, 2017 | 54 | 2017 |
| Models for dioxygen activation by the CuB site of dopamine β-monooxygenase and peptidylglycine α-hydroxylating monooxygenase BF Gherman, DE Heppner, WB Tolman, CJ Cramer JBIC Journal of Biological Inorganic Chemistry 11, 197-205, 2006 | 54 | 2006 |
| Molecular origin of rapid versus slow intramolecular electron transfer in the catalytic cycle of the multicopper oxidases DE Heppner, CH Kjaergaard, EI Solomon Journal of the American Chemical Society 135 (33), 12212-12215, 2013 | 50 | 2013 |
| Paradoxical Roles of Dual Oxidases in Cancer Biology AC Little, A Sulovari, K Danyal, DE Heppner, DJ Seward, A van der Vliet Free Radical Biology and Medicine 110, 117-132, 2017 | 48 | 2017 |
Albert van der VlietProfessor of Pathology, University of Vermont在 uvm.edu 的电子邮件经过验证
