Antagonism of SET using OP449 enhances the efficacy of tyrosine kinase inhibitors and overcomes drug resistance in myeloid leukemia A Agarwal, RJ MacKenzie, R Pippa, CA Eide, J Oddo, JW Tyner, R Sears, ... Clinical cancer research 20 (8), 2092-2103, 2014 | 149 | 2014 |
Nuclear pores promote lethal prostate cancer by increasing POM121-driven E2F1, MYC, and AR nuclear import V Rodriguez-Bravo, R Pippa, WM Song, M Carceles-Cordon, ... Cell 174 (5), 1200-1215. e20, 2018 | 124 | 2018 |
p27Kip1 represses transcription by direct interaction with p130/E2F4 at the promoters of target genes R Pippa, L Espinosa, G Gundem, R Garcia-Escudero, A Dominguez, ... Oncogene 31 (38), 4207-4220, 2012 | 94 | 2012 |
Effect of FTY720 on the SET–PP2A complex in acute myeloid leukemia; SET binding drugs have antagonistic activity R Pippa, A Dominguez, DJ Christensen, I Moreno-Miralles, ... Leukemia 28 (9), 1915-1918, 2014 | 74 | 2014 |
SARS-CoV-2 ORF9c is a membrane-associated protein that suppresses antiviral responses in cells A Dominguez Andres, Y Feng, AR Campos, J Yin, CC Yang, B James, ... BioRxiv, 2020.08. 18.256776, 2020 | 69 | 2020 |
Protein phosphatase 2A as a therapeutic target in acute myeloid leukemia E Arriazu, R Pippa, MD Odero Frontiers in oncology 6, 78, 2016 | 66 | 2016 |
Inactivation of NF-κB by proteasome inhibition contributes to increased apoptosis induced by histone deacetylase inhibitors in human breast cancer cells J Domingo-Domenech, R Pippa, M Tápia, P Gascón, O Bachs, M Bosch Breast cancer research and treatment 112, 53-62, 2008 | 57 | 2008 |
A new regulatory mechanism of protein phosphatase 2A activity via SET in acute myeloid leukemia E Arriazu, C Vicente, R Pippa, I Peris, E Martínez-Balsalobre, ... Blood cancer journal 10 (1), 3, 2020 | 38 | 2020 |
Small extracellular vesicles modulated by αVβ3 integrin induce neuroendocrine differentiation in recipient cancer cells F Quaglia, SR Krishn, GG Daaboul, S Sarker, R Pippa, ... Journal of Extracellular Vesicles 9 (1), 1761072, 2020 | 38 | 2020 |
The role of MYC and PP2A in the initiation and progression of myeloid leukemias R Pippa, MD Odero Cells 9 (3), 544, 2020 | 34 | 2020 |
Combined targeting of SET and tyrosine kinases provides an effective therapeutic approach in human T-cell acute lymphoblastic leukemia AA Richard NP, Pippa R, Cleary MM, Puri A, Tibbitts D, Mahmood S ... Oncotarget, 2016 | 33 | 2016 |
A novel FTY720 analogue targets SET-PP2A interaction and inhibits growth of acute myeloid leukemia cells without inducing cardiac toxicity C Vicente, E Arriazu, E Martínez-Balsalobre, I Peris, N Marcotegui, ... Cancer Letters 468, 1-13, 2020 | 32 | 2020 |
MYC-dependent recruitment of RUNX1 and GATA2 on the SET oncogene promoter enhances PP2A inactivation in acute myeloid leukemia R Pippa, A Dominguez, R Malumbres, A Endo, E Arriazu, N Marcotegui, ... Oncotarget 8 (33), 53989, 2016 | 32 | 2016 |
CIP2A high expression is a poor prognostic factor in normal karyotype acute myeloid leukemia E Barragán, MC Chillón, R Castelló-Cros, N Marcotegui, MI Prieto, ... Haematologica 100 (5), e183, 2015 | 29 | 2015 |
New insights on the transcriptional regulation of CD69 gene through a potent enhancer located in the conserved non-coding sequence 2 T Laguna, L Notario, R Pippa, MG Fontela, BN Vázquez, M Maicas, ... Molecular Immunology 66 (2), 171-179, 2015 | 25 | 2015 |
Urine extracellular vesicle GATA2 mRNA discriminates biopsy result in men with suspicion of prostate cancer J Woo, S Santasusagna, J Banks, S Pastor-Lopez, K Yadav, ... The Journal of urology 204 (4), 691-700, 2020 | 24 | 2020 |
Lipid nanosystems enhance the bioavailability and the therapeutic efficacy of FTY720 in acute myeloid leukemia A de Mendoza, R Castello-Cros, E Imbuluzqueta, C Cirauqui, R Pippa, ... Journal of Biomedical Nanotechnology 11 (4), 691-701, 2015 | 23 | 2015 |
The Chromatin Assembly Factor Complex 1 (CAF1) and 5-Azacytidine (5-AzaC) Affect Cell Motility in Src-transformed Human Epithelial Cells LAI Endo A, Ly T, Pippa R, Bensaddek D, Nicolas A Journal of Biochemical Chemistry, 2016 | 17* | 2016 |
Data mining analysis of the PP2A cell cycle axis in mesothelioma patients R Pippa, S Boffo, MD Odero, A Giordano Journal of Cellular Physiology 235 (6), 5284-5292, 2020 | 4 | 2020 |
GATA2 exosomal mRNA: A novel urine biomarker for the diagnosis of clinically significant prostate cancer. J Woo, S Santasusagna, B Leiby, KK Yadav, A Dominguez-Andres, ... Journal of Clinical Oncology 37 (7_suppl), 18-18, 2019 | 3 | 2019 |