A survey of the anti-apoptotic Bcl-2 subfamily expression in cancer types provides a platform to predict the efficacy of Bcl-2 antagonists in cancer therapy WJ Placzek, J Wei, S Kitada, D Zhai, JC Reed, M Pellecchia Cell death & disease 1 (5), e40-e40, 2010 | 357 | 2010 |
The E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity J Qi, M Tripathi, R Mishra, N Sahgal, L Fazil, S Ettinger, WJ Placzek, ... Cancer cell 23 (3), 332-346, 2013 | 158 | 2013 |
Post-transcriptional regulation of anti-apoptotic BCL2 family members J Cui, WJ Placzek International journal of molecular sciences 19 (1), 308, 2018 | 149 | 2018 |
BI-97C1, an optically pure Apogossypol derivative as pan-active inhibitor of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins J Wei, JL Stebbins, S Kitada, R Dash, W Placzek, MF Rega, B Wu, ... Journal of medicinal chemistry 53 (10), 4166-4176, 2010 | 137 | 2010 |
Novel targeted system to deliver chemotherapeutic drugs to EphA2-expressing cancer cells S Wang, WJ Placzek, JL Stebbins, S Mitra, R Noberini, M Koolpe, Z Zhang, ... Journal of medicinal chemistry 55 (5), 2427-2436, 2012 | 94 | 2012 |
Serum galactose-deficient-IgA1 and IgG autoantibodies correlate in patients with IgA nephropathy WJ Placzek, H Yanagawa, Y Makita, MB Renfrow, BA Julian, DV Rizk, ... PLoS One 13 (1), e0190967, 2018 | 83 | 2018 |
The multiple mechanisms of MCL1 in the regulation of cell fate H Widden, WJ Placzek Communications Biology 4 (1), 1029, 2021 | 69 | 2021 |
14-3-3 proteins reduce cell-to-cell transfer and propagation of pathogenic α-synuclein B Wang, R Underwood, A Kamath, C Britain, MB McFerrin, PJ McLean, ... Journal of Neuroscience 38 (38), 8211-8232, 2018 | 64 | 2018 |
Volatile anesthetics bind rat synaptic snare proteins P Nagele, JB Mendel, WJ Placzek, BA Scott, DA d'Avignon, CM Crowder The Journal of the American Society of Anesthesiologists 103 (4), 768-778, 2005 | 58 | 2005 |
An optically pure apogossypolone derivative as potent pan-active inhibitor of anti-apoptotic bcl-2 family proteins J Wei, JL Stebbins, S Kitada, R Dash, D Zhai, WJ Placzek, B Wu, ... Frontiers in oncology 1, 28, 2011 | 57 | 2011 |
Regulating the BCL2 family to improve sensitivity to microtubule targeting agents RH Whitaker, WJ Placzek Cells 8 (4), 346, 2019 | 50 | 2019 |
PTBP1 modulation of MCL1 expression regulates cellular apoptosis induced by antitubulin chemotherapeutics J Cui, WJ Placzek Cell Death & Differentiation 23 (10), 1681-1690, 2016 | 47 | 2016 |
Sabutoclax, a Mcl-1 antagonist, inhibits tumorigenesis in transgenic mouse and human xenograft models of prostate cancer RS Jackson II, W Placzek, A Fernandez, S Ziaee, CY Chu, J Wei, ... Neoplasia 14 (7), 656-IN24, 2012 | 47 | 2012 |
Synthesis and biological evaluation of Apogossypolone derivatives as pan-active inhibitors of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins J Wei, S Kitada, JL Stebbins, W Placzek, D Zhai, B Wu, MF Rega, Z Zhang, ... Journal of medicinal chemistry 53 (22), 8000-8011, 2010 | 47 | 2010 |
Identification of a novel Mcl-1 protein binding motif WJ Placzek, M Sturlese, B Wu, JF Cellitti, J Wei, M Pellecchia Journal of Biological Chemistry 286 (46), 39829-39835, 2011 | 45 | 2011 |
The GTPase Rab27b regulates the release, autophagic clearance, and toxicity of α-synuclein R Underwood, B Wang, C Carico, RH Whitaker, WJ Placzek, ... Journal of Biological Chemistry 295 (23), 8005-8016, 2020 | 28 | 2020 |
PTBP1 enhances miR-101-guided AGO2 targeting to MCL1 and promotes miR-101-induced apoptosis J Cui, WJ Placzek Cell death & disease 9 (5), 552, 2018 | 28 | 2018 |
Cold-adaptation in sea-water-borne signal proteins: sequence and NMR structure of the pheromone En-6 from the Antarctic ciliate Euplotes nobilii B Pedrini, WJ Placzek, E Koculi, C Alimenti, A LaTerza, P Luporini, ... Journal of molecular biology 372 (2), 277-286, 2007 | 28 | 2007 |
Specific inhibition of DPY30 activity by ASH2L-derived peptides suppresses blood cancer cell growth KK Shah, RH Whitaker, T Busby, J Hu, B Shi, Z Wang, C Zang, ... Experimental cell research 382 (2), 111485, 2019 | 23 | 2019 |
Novel EGFR ectodomain mutations associated with ligand-independent activation and cetuximab resistance in head and neck cancer S Nair, HQ Trummell, R Rajbhandari, NK Thudi, SE Nozell, JM Warram, ... PLoS One 15 (2), e0229077, 2020 | 21 | 2020 |