Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients J Hadjadj, N Yatim, L Barnabei, A Corneau, J Boussier, N Smith, H Péré, ... Science 369 (6504), 718-724, 2020 | 3128 | 2020 |
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 Q Zhang, P Bastard, Z Liu, J Le Pen, M Moncada-Velez, J Chen, M Ogishi, ... Science 370 (6515), eabd4570, 2020 | 2329 | 2020 |
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ... Science immunology 6 (62), eabl4340, 2021 | 530 | 2021 |
X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19 T Asano, B Boisson, F Onodi, D Matuozzo, M Moncada-Velez, ... Science immunology 6 (62), eabl4348, 2021 | 380 | 2021 |
Sheffield COVID-19 Genomics Group B Korber, WM Fischer, S Gnanakaran, H Yoon, J Theiler, W Abfalterer, ... Tracking changes in SARS-CoV-2 spike: evidence that D614G increases …, 2020 | 272 | 2020 |
Sex differences in plasmacytoid dendritic cell levels of IRF5 drive higher IFN-α production in women M Griesbeck, S Ziegler, S Laffont, N Smith, L Chauveau, P Tomezsko, ... The Journal of Immunology 195 (11), 5327-5336, 2015 | 237 | 2015 |
SARS-CoV-2 infection induces the dedifferentiation of multiciliated cells and impairs mucociliary clearance R Robinot, M Hubert, GD de Melo, F Lazarini, T Bruel, N Smith, ... Nature communications 12 (1), 4354, 2021 | 200 | 2021 |
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies J Manry, P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, ... Proceedings of the National Academy of Sciences 119 (21), 2022 | 160 | 2022 |
Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection N Smith, P Goncalves, B Charbit, L Grzelak, M Beretta, C Planchais, ... Nature immunology 22 (11), 1428-1439, 2021 | 149 | 2021 |
COVID-STORM Clinicians; COVID Clinicians; Imagine COVID Group; French COVID Cohort Study Group; CoV-Contact Cohort; Amsterdam UMC Covid-19 Biobank; COVID Human Genetic Effort Q Zhang, P Bastard, Z Liu, J Le Pen, M Moncada-Velez, J Chen, M Ogishi, ... Science 370, eabd4570, 2020 | 88 | 2020 |
Dengue Virus Activates Membrane TRAIL Relocalization and IFN-α Production by Human Plasmacytoid Dendritic Cells In Vitro and In Vivo M Gandini, C Gras, EL Azeredo, LMO Pinto, N Smith, P Despres, ... PLoS neglected tropical diseases 7 (6), e2257, 2013 | 85 | 2013 |
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19. Science. 370: eabd4570 Q Zhang, P Bastard, Z Liu, J Le Pen, M Moncada-Velez, J Chen, M Ogishi, ... Link: https://bit. ly/3z1640Z, 2020 | 79 | 2020 |
HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses S Langer, C Hammer, K Hopfensperger, L Klein, D Hotter, PD De Jesus, ... Elife 8, e41930, 2019 | 78 | 2019 |
A monocyte/dendritic cell molecular signature of SARS-CoV-2-related multisystem inflammatory syndrome in children with severe myocarditis C de Cevins, M Luka, N Smith, S Meynier, A Magérus, F Carbone, ... Med 2 (9), 1072-1092. e7, 2021 | 63 | 2021 |
Design, Synthesis, and Evaluation of Novel Imidazo[1,2-a][1,3,5]triazines and Their Derivatives as Focal Adhesion Kinase Inhibitors with Antitumor Activity P Dao, N Smith, C Tomkiewicz-Raulet, E Yen-Pon, M Camacho-Artacho, ... Journal of medicinal chemistry 58 (1), 237-251, 2015 | 60 | 2015 |
TRIM8 is required for virus-induced IFN response in human plasmacytoid dendritic cells G Maarifi, N Smith, S Maillet, O Moncorgé, C Chamontin, J Edouard, ... Science advances 5 (11), eaax3511, 2019 | 52 | 2019 |
Control of TLR7-mediated type I IFN signaling in pDCs through CXCR4 engagement—a new target for lupus treatment N Smith, MP Rodero, N Bekaddour, V Bondet, YB Ruiz-Blanco, M Harms, ... Science Advances 5 (7), eaav9019, 2019 | 47 | 2019 |
Defective activation and regulation of type I interferon immunity is associated with increasing COVID-19 severity N Smith, C Possémé, V Bondet, J Sugrue, L Townsend, B Charbit, ... Nature communications 13 (1), 7254, 2022 | 46 | 2022 |
Interleukin‐7/Interferon Axis Drives T Cell and Salivary Gland Epithelial Cell Interactions in Sjögren’s Syndrome E Rivière, J Pascaud, A Virone, A Dupré, B Ly, A Paoletti, R Seror, ... Arthritis & rheumatology 73 (4), 631-640, 2021 | 46 | 2021 |
Type I interferon response and vascular alteration in chilblain‐like lesions during the COVID‐19 outbreak L Frumholtz, JD Bouaziz, M Battistella, J Hadjadj, R Chocron, D Bengoufa, ... British Journal of Dermatology 185 (6), 1176-1185, 2021 | 44 | 2021 |