T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming K Yang, S Shrestha, H Zeng, PWF Karmaus, G Neale, P Vogel, ... Immunity 39 (6), 1043-1056, 2013 | 384 | 2013 |
Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells X Du, J Wen, Y Wang, PWF Karmaus, A Khatamian, H Tan, Y Li, C Guy, ... Nature 558 (7708), 141-145, 2018 | 169 | 2018 |
Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity PWF Karmaus, X Chen, SA Lim, AA Herrada, TLM Nguyen, B Xu, ... Nature 565 (7737), 101-105, 2019 | 166 | 2019 |
Tsc1 promotes the differentiation of memory CD8+ T cells via orchestrating the transcriptional and metabolic programs S Shrestha, K Yang, J Wei, PWF Karmaus, G Neale, H Chi Proceedings of the National Academy of Sciences 111 (41), 14858-14863, 2014 | 83 | 2014 |
Histone crotonylation promotes mesoendodermal commitment of human embryonic stem cells Y Fang, X Xu, J Ding, L Yang, MT Doan, PWF Karmaus, NW Snyder, ... Cell Stem Cell 28 (4), 748-763. e7, 2021 | 79 | 2021 |
IRGM1 links mitochondrial quality control to autoimmunity P Rai, KS Janardhan, J Meacham, JH Madenspacher, WC Lin, ... Nature immunology 22 (3), 312-321, 2021 | 78 | 2021 |
Modulation of airway responses to influenza A/PR/8/34 by Δ9-tetrahydrocannabinol in C57BL/6 mice JP Buchweitz, PWF Karmaus, JR Harkema, KJ Williams, NE Kaminski Journal of Pharmacology and Experimental Therapeutics 323 (2), 675-683, 2007 | 75 | 2007 |
Cannabidiol (CBD) enhances lipopolysaccharide (LPS)-induced pulmonary inflammation in C57BL/6 mice PWF Karmaus, JG Wagner, JR Harkema, NE Kaminski, BLF Kaplan Journal of immunotoxicology 10 (3), 321-328, 2013 | 66 | 2013 |
Targeted deletion of cannabinoid receptors CB1 and CB2 produced enhanced inflammatory responses to influenza A/PR/8/34 in the absence and presence of Δ9-tetrahydrocannabinol JP Buchweitz, PWF Karmaus, KJ Williams, JR Harkema, NE Kaminski Journal of Leucocyte Biology 83 (3), 785-796, 2008 | 64 | 2008 |
mTOR and metabolic regulation of conventional and regulatory T cells C Liu, NM Chapman, PWF Karmaus, H Zeng, H Chi Journal of Leucocyte Biology 97 (5), 837-847, 2015 | 63 | 2015 |
Δ9-Tetrahydrocannabinol Impairs the Inflammatory Response to Influenza Infection: Role of Antigen-Presenting Cells and the Cannabinoid Receptors 1 and 2 PWF Karmaus, W Chen, R Crawford, BLF Kaplan, NE Kaminski toxicological sciences 131 (2), 419-433, 2013 | 61 | 2013 |
Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF–mediated myelopoiesis PWF Karmaus, AA Herrada, C Guy, G Neale, Y Dhungana, L Long, ... Journal of Experimental Medicine 214 (9), 2629-2647, 2017 | 49 | 2017 |
Effects of targeted deletion of cannabinoid receptors CB1 and CB2 on immune competence and sensitivity to immune modulation by Δ9-tetrahydrocannabinol AEB Springs, PWF Karmaus, RB Crawford, BLF Kaplan, NE Kaminski Journal of Leucocyte Biology 84 (6), 1574-1584, 2008 | 48 | 2008 |
CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation G Izumi, H Nakano, K Nakano, GS Whitehead, SA Grimm, MB Fessler, ... Nature communications 12 (1), 5029, 2021 | 46 | 2021 |
Critical role of caspase-8-mediated IL-1 signaling in promoting Th2 responses during asthma pathogenesis X Qi, P Gurung, RKS Malireddi, PWF Karmaus, D Sharma, P Vogel, H Chi, ... Mucosal immunology 10 (1), 128-138, 2017 | 45 | 2017 |
Deletion of cannabinoid receptors 1 and 2 exacerbates APC function to increase inflammation and cellular immunity during influenza infection PWF Karmaus, W Chen, RB Crawford, JR Harkema, BLF Kaplan, ... Journal of leukocyte biology 90 (5), 983-995, 2011 | 43 | 2011 |
Δ9-Tetrahydrocannabinol Suppresses Cytotoxic T Lymphocyte Function Independent of CB1 and CB2, Disrupting Early Activation Events PWF Karmaus, W Chen, BLF Kaplan, NE Kaminski Journal of Neuroimmune Pharmacology 7, 843-855, 2012 | 30 | 2012 |
Effects of rosuvastatin on the immune system in healthy volunteers with normal serum cholesterol PWF Karmaus, M Shi, S Perl, A Biancotto, J Candia, F Cheung, ... JCI insight 4 (21), 2019 | 18 | 2019 |
The Effects of Targeted Deletion of Cannabinoid Receptors CB1 and CB2 on Intranasal Sensitization and Challenge with Adjuvant-free Ovalbumin BLF Kaplan, JE Lawver, PWF Karmaus, T Ngaotepprutaram, ... Toxicologic pathology 38 (3), 382-392, 2010 | 15 | 2010 |
2, 2′, 4, 4′-Tetrachlorobiphenyl upregulates cyclooxygenase-2 in HL-60 cells via p38 mitogen-activated protein kinase and NF-κB SA Bezdecny, P Karmaus, RA Roth, PE Ganey Toxicology and applied pharmacology 221 (3), 285-294, 2007 | 11 | 2007 |